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PDB: 1192 件

3DTX
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Crystal structure of HLA-B*2705 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408)
分子名称: Beta-2-microglobulin, Double citrullinated vasoactive intestinal polypeptide receptor, MHC class I antigen (Fragment)
著者Beltrami, A, Gabdulkhakov, A, Rossmann, M, Ziegler, A, Uchanska-Ziegler, B, Saenger, W.
登録日2008-07-16
公開日2009-05-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Citrullination-and mhc polymorphism-dependent conformational changes of a self peptide
To be Published
4NO5
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Crystal structure of non-phosphorylated form of AMPD2 phosphopeptide bound to HLA-A2
分子名称: 1,2-ETHANEDIOL, AMP deaminase 2, Beta-2-microglobulin, ...
著者Mohammed, F, Stones, D.H, Willcox, B.E.
登録日2013-11-19
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
4NNX
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Crystal structure of PKD2 phosphopeptide bound to HLA-A2
分子名称: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ...
著者Mohammed, F, Stones, D.H, Willcox, B.E.
登録日2013-11-19
公開日2014-11-19
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
6SSA
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Human Leukocyte Antigen Class I A02 Carrying LLWNGPMQV
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CALCIUM ION, ...
著者Rizkallah, P.J, Bovay, A.
登録日2019-09-06
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222by combinatorial peptide library screening.
Mol.Immunol., 125, 2020
7MXH
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CD1c with antigen analogue 3
分子名称: (2S)-2,3-dihydroxypropyl hexadecanoate, 2,6-anhydro-1-deoxy-1,1-difluoro-1-[(R)-hydroxy{[(4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-D-glycero-D-galacto-heptitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cao, T.P, Shahine, A, Rossjohn, J.
登録日2021-05-19
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.
J.Biol.Chem., 297, 2021
1W0W
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Crystal Structure Of HLA-B*2709 Complexed With the self-Peptide TIS from EGF-response factor 1
分子名称: BETA-2-MICROGLOBULIN, BUTYRATE RESPONSE FACTOR 2, GLYCEROL, ...
著者Hulsmeyer, M, Fiorillo, M.T, Bettosini, F, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
登録日2004-06-14
公開日2005-03-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Thermodynamic and Structural Equivalence of Two Hla-B27 Subtypes Complexed with a Self-Peptide
J.Mol.Biol., 346, 2005
7EJN
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Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-HKU1) spike protein
分子名称: 9-mer peptide from the HCoV spike protein, Beta-2-microglobulin, MHC class I antigen
著者Murayama, K, Kato-Murayama, M, Shirouzu, M.
登録日2021-04-02
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2.
Commun Biol, 4, 2021
8EK5
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Engineered scFv 10LH bound to PHOX2B/HLA-A24:02
分子名称: 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ...
著者Garfinkle, S.E, Florio, T.J, Sgourakis, N.G.
登録日2022-09-20
公開日2023-12-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.
Sci Immunol, 8, 2023
4JFO
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A2 HLA complex with E1A heteroclitic variant of Melanoma peptide
分子名称: Beta-2-microglobulin, E1A heteroclitic Melanoma peptide, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K, Baker, B.M.
登録日2013-02-28
公開日2013-05-29
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
5C07
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1E6 TCR in complex with HLA-A02 carrying YQFGPDFPIA
分子名称: 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ...
著者Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
登録日2015-06-12
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5EU4
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HLA Class I antigen
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
登録日2015-11-18
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
7RRG
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BU of 7rrg by Molmil
Crystal structure of human 0606T1-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Ma, J, Baker, B.M.
登録日2021-08-09
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
3GSQ
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BU of 3gsq by Molmil
Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5S peptide variant
分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5S (NLVPSVATV), ...
著者Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
7ZT9
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BU of 7zt9 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 4FBA
分子名称: 1,2-ETHANEDIOL, 4-METHYLBENZOIC ACID, Beta-2-microglobulin, ...
著者Karuppiah, V, Srikannathasan, V, Robinson, R.A.
登録日2022-05-09
公開日2023-06-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
5IND
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BU of 5ind by Molmil
Crystal structure of HLA-B5801, a protective HLA allele for HIV-1 infection
分子名称: Beta-2-microglobulin, GLN-ALA-SER-GLN-ASP-VAL-LYS-ASN-TRP, HLA class I histocompatibility antigen, ...
著者Li, X, Wang, J.-H.
登録日2016-03-07
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.132 Å)
主引用文献Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection.
Protein Cell, 7, 2016
6PVD
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BU of 6pvd by Molmil
Structure of human MAIT A-F7 TCR in complex with human MR1-NV18.1
分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
著者Awad, W, Rossjohn, J.
登録日2019-07-20
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Ligand-dependent downregulation of MR1 cell surface expression.
Proc.Natl.Acad.Sci.USA, 117, 2020
5NQ1
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BU of 5nq1 by Molmil
Porcine (Sus scrofa) Major Histocompatibility Complex, class I, with human beta2 micro globulin, presenting DFEREGYSL
分子名称: 1,2-ETHANEDIOL, ASP-PHE-GLU-ARG-GLU-GLY-TYR-SER-LEU, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Tungatt, K, Sewell, A.K.
登録日2017-04-19
公開日2018-04-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig.
Plos Pathog., 14, 2018
6VB5
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HLA-B*15:02 complexed with a synthetic peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
著者Schutte, R.J, Li, D, Ostrov, D.A.
登録日2019-12-18
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献HLA-B*15:02 complexed with a synthetic peptide
To Be Published
6VB6
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HLA-B*15:02 complexed with a synthetic peptide
分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
著者Schutte, R.J, Li, D, Ostrov, D.A.
登録日2019-12-18
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献HLA-B*15:02 complexed with a synthetic peptide
To Be Published
1DUY
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BU of 1duy by Molmil
CRYSTAL STRUCTURE OF HLA-A*0201/OCTAMERIC TAX PEPTIDE COMPLEX
分子名称: BETA-2 MICROGLOBULIN, HLA-A2*0201, HTLV-1 OCTAMERIC TAX PEPTIDE
著者Khan, A.R, Baker, B.M, Ghosh, P, Biddison, W.E, Wiley, D.C.
登録日2000-01-19
公開日2000-02-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site.
J.Immunol., 164, 2000
6PTB
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BU of 6ptb by Molmil
Crystal Structure of ILNAMIAKI peptide bound to HLA-A2
分子名称: Beta-2-microglobulin, GLYCEROL, HAUS augmin-like complex subunit 3, ...
著者Keller, G.L.J, Arbuiso, A, Baker, B.M.
登録日2019-07-15
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
7KGO
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BU of 7kgo by Molmil
Crystal Structure of HLA-A*0201in complex with SARS-CoV-2 N351-359
分子名称: Beta-2-microglobulin, CADMIUM ION, CHLORIDE ION, ...
著者Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S.
登録日2020-10-18
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The presentation of SARS-CoV-2 peptides by the common HLA-A * 02:01 molecule.
Iscience, 24, 2021
5U17
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Structure of human MR1-DA-6-FP in complex with human MAIT A-F7 TCR
分子名称: 2,4-diaminopteridine-6-carbaldehyde, ACETATE ION, Beta-2-microglobulin, ...
著者Keller, A.N, Rossjohn, J.
登録日2016-11-28
公開日2017-02-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Nat. Immunol., 18, 2017
1W72
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Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3
分子名称: BETA-2-MICROGLOBULIN, GLYCEROL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Hulsmeyer, M, Chames, P, Hillig, R.C, Stanfield, R.L, Held, G, Coulie, P.G, Alings, C, Wille, G, Saenger, W, Uchanska-Ziegler, B, Hoogenboom, H.R, Ziegler, A.
登録日2004-08-27
公開日2004-11-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A Major Histocompatibility Complex.Peptide- Restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: Crystal Structure of Human Leukocyte Antigen (Hla)-A1.Mage-A1 in Complex with Fab-Hyb3
J.Biol.Chem., 280, 2005
1ONQ
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Crystal Structure of CD1a in Complex with a Sulfatide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Zajonc, D.M, Elsliger, M.A, Teyton, L, Wilson, I.A.
登録日2003-02-28
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A.
Nat.Immunol., 4, 2003

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