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PDB: 1179 件

5WMN
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BU of 5wmn by Molmil
Crystal Structure of HLA-B7 in complex with SPI, an influenza peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Gras, S, Rossjohn, J.
登録日2017-07-30
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
J. Immunol., 200, 2018
8GLH
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BU of 8glh by Molmil
Crystal Structure of Human CD1b in Complex with Endogenous PC C40:5
分子名称: (11E)-hexadec-11-enoic acid, 1,2-ETHANEDIOL, Beta-2-microglobulin, ...
著者Farquhar, R, Rossjohn, J, Shahine, A.
登録日2023-03-22
公開日2023-09-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Cell, 186, 2023
5DEG
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BU of 5deg by Molmil
Crystal structure of B*27:06 bound to the pVIPR peptide
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Loll, B, Fabian, H, Hee, C.S, Huser, H, Uchanska-Ziegler, B, Ziegler, A.
登録日2015-08-25
公開日2015-11-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis.
Arthritis Rheumatol, 68, 2016
6D2R
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BU of 6d2r by Molmil
HLA-B*57:01 presenting GSFDYSGVHLW
分子名称: Beta-2-microglobulin, GLY-SER-PHE-ASP-TYR-SER-GLY-VAL-HIS-LEU-TRP, HLA class I histocompatibility antigen, ...
著者Vivian, J.P, Rossjohn, J.
登録日2018-04-13
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.
Sci Immunol, 3, 2018
8EMG
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BU of 8emg by Molmil
Crystal structure of a HLA-B*35:01-NP7 epitope from 2002 H2N1 influenza strain
分子名称: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ...
著者Littler, D.R, Rossjohn, J.
登録日2022-09-27
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.83001268 Å)
主引用文献Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors
To Be Published
7ZT7
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BU of 7zt7 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 5FSA
分子名称: 1,2-ETHANEDIOL, 2-hydroxy-5-methylbenzoic acid, Beta-2-microglobulin, ...
著者Karuppiah, V, Robinson, R.A.
登録日2022-05-09
公開日2023-06-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
8XG2
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BU of 8xg2 by Molmil
The structure of HLA-A/Pep14
分子名称: Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1
著者Zhang, J.N, Yue, C, Liu, J.
登録日2023-12-14
公開日2024-07-10
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
6PUL
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BU of 6pul by Molmil
Structure of human MAIT A-F7 TCR in complex with human MR1 3'D-5-OP-RU
分子名称: 1,3-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol, ACETATE ION, Beta-2-microglobulin, ...
著者Awad, W, Keller, A.N, Rossjohn, J.
登録日2019-07-18
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Nat.Immunol., 21, 2020
3KPQ
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BU of 3kpq by Molmil
Crystal Structure of HLA B*4405 in complex with EEYLKAWTF, a mimotope
分子名称: Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
4NT6
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BU of 4nt6 by Molmil
HLA-C*0801 Crystal Structure
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, Cw-8 alpha chain, ...
著者Liu, J.X, Toh, X.Y, Ren, E.C.
登録日2013-12-01
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献The immunodominant influenza A virus M158-66 cytotoxic T lymphocyte epitope exhibits degenerate class I major histocompatibility complex restriction in humans.
J.Virol., 88, 2014
8GLE
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BU of 8gle by Molmil
Crystal Structure of Human CD1b in Complex with Lysosulfatide
分子名称: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl 3-O-sulfo-beta-D-galactopyranoside, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shahine, A.
登録日2023-03-22
公開日2023-09-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Cell, 186, 2023
4Z77
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BU of 4z77 by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2015-04-06
公開日2015-06-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
To Be Published
3VFR
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BU of 3vfr by Molmil
crystal structure of HLA B*3508LPEP-P4Ala, peptide mutant P4-ala
分子名称: Beta-2-microglobulin, LPEP peptide from EBV, P4A, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
8ELH
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BU of 8elh by Molmil
Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANQF from SARS-CoV-2 virus
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Murdolo, L.D, Gras, S.
登録日2022-09-24
公開日2023-06-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.
Nature, 620, 2023
5ENW
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BU of 5enw by Molmil
Structure of HLA-A2:01 with peptide G9L
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Remesh, S.G, Zajonc, D.M.
登録日2015-11-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
7SA2
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BU of 7sa2 by Molmil
SARS-CoV-2 spike-derived peptide S1060-1068 (VVFLHVTYV) presented by HLA-A*02:01
分子名称: Beta-2-microglobulin, CADMIUM ION, MHC class I antigen, ...
著者Szeto, C, Gras, S.
登録日2021-09-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献SARS-CoV-2 spike-derived peptide S1060-1068 (VVFLHVTYV) presented by HLA-A*02:01
To Be Published
3VFS
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BU of 3vfs by Molmil
crystal structure of HLA B*3508LPEP-P5Ala , peptide mutant P5-ala
分子名称: Beta-2-microglobulin, LPEP peptide from EBV, P5A, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
3VFP
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BU of 3vfp by Molmil
crystal structure of HLA B*3508 LPEP158G, HLA mutant Gly158
分子名称: ACETATE ION, Beta-2-microglobulin, LPEP peptide from EBV, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
7N4K
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BU of 7n4k by Molmil
6218 TCR in complex with H2-Db PA 224
分子名称: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ...
著者Szeto, C, Gras, S.
登録日2021-06-04
公開日2022-07-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Nat Commun, 13, 2022
2HJK
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BU of 2hjk by Molmil
Crystal Structure of HLA-B5703 and HIV-1 peptide
分子名称: Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen B-57
著者Gillespie, G.M.A, Stewart-Jones, G, Rengasamy, J, Beattie, T, Bwayo, J.J, Plummer, F.A.
登録日2006-06-30
公開日2006-10-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection.
J.Immunol., 177, 2006
6C98
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BU of 6c98 by Molmil
Crystal structure of FcRn bound to UCB-84
分子名称: 1-[7-(3-fluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethan-1-one, Beta-2-microglobulin, CYSTEINE, ...
著者Fox III, D, Lukacs, C.M.
登録日2018-01-25
公開日2018-05-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
6PUC
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BU of 6puc by Molmil
Structure of human MAIT A-F7 TCR in complex with human MR1-5-OP-RU
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, CHLORIDE ION, ...
著者Awad, W, Rossjohn, J.
登録日2019-07-18
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Nat.Immunol., 21, 2020
3BP4
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BU of 3bp4 by Molmil
The high resolution crystal structure of HLA-B*2705 in complex with a Cathepsin A signal sequence peptide pCatA
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Kumar, P, Vahedi-Faridi, A, Saenger, W, Uchanska-Ziegler, B, Ziegler, A.
登録日2007-12-18
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
J.Biol.Chem., 284, 2009
3O3E
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BU of 3o3e by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2.1
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-07-23
公開日2010-12-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
5EO1
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BU of 5eo1 by Molmil
Crystal Structure of HLA-B0702-RL9
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Josephs, T.M, Gras, S, Rossjohn, J.
登録日2015-11-10
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.
J Immunol., 196, 2016

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件を2024-07-10に公開中

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