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PDB: 1180 件

2VLL
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The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain
分子名称: BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y.
登録日2008-01-15
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
5WMP
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Crystal Structure of HLA-B7 in complex with TPR, a CMV peptide
分子名称: Beta-2-microglobulin, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Gras, S, Rossjohn, J.
登録日2017-07-30
公開日2018-06-06
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
J. Immunol., 200, 2018
3BGM
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BU of 3bgm by Molmil
Crystal Structure of PKD2 Phosphopeptide Bound to Human Class I MHC HLA-A2
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Mohammed, F, Cobbold, M, Zarling, A.L, Salim, M, Barrett-Wilt, G.A, Shabanowitz, J, Hunt, D.F, Engelhard, V.H, Willcox, B.E.
登録日2007-11-27
公開日2008-10-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self
Nat.Immunol., 9, 2008
3MRR
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BU of 3mrr by Molmil
Crystal Structure of MHC class I HLA-A2 molecule complexed with Human Prostaglandin Transporter decapeptide
分子名称: 10-meric peptide from Solute carrier organic anion transporter family member 2A1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Reiser, J.-B, Machillot, P, Chouquet, A, Debeaupuis, E, Echasserieau, K, Legoux, F, Saulquin, X, Bonneville, M, Housset, D.
登録日2010-04-29
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans.
J.Immunol., 193, 2014
3PWN
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Human Class I MHC HLA-A2 in complex with the HuD (G2L) peptide variant
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-12-08
公開日2011-03-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
4QRU
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Crystal Structure of HLA B*0801 in complex with ELR_MYM, ELRRKMMYM
分子名称: 55 kDa immediate-early protein 1, ACETATE ION, Beta-2-microglobulin, ...
著者Gras, S, Twist, K.-A, Rossjohn, J.
登録日2014-07-02
公開日2015-02-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.
Sci Rep, 4, 2014
3DX7
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Crystal Structure of HLA-B*4403 presenting 10mer EBV antigen
分子名称: ACETATE ION, Beta-2-microglobulin, EBV decapeptide epitope, ...
著者Archbold, J.K, Ely, L.K, Rossjohn, J.
登録日2008-07-23
公開日2009-01-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
J.Exp.Med., 206, 2009
4LCY
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Crystal structure of HLA-b46 at 1.6 angstrom resolution
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-46 alpha chain, ...
著者Liu, J.X.
登録日2013-06-24
公開日2014-06-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure Analysis of the Human Leukocyte Antigen B*46:01
To be Published
8FU4
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HCMV US11 peptide binding to HLA-A*02:01
分子名称: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ...
著者Watson, G.M, Berry, R, Littler, D.R, Rossjohn, J.
登録日2023-01-16
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids.
Proc.Natl.Acad.Sci.USA, 121, 2024
8RNH
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Crystal structure of HLA B*18:01 in complex with EEIEITTHF, an 9-mer epitope from Influenza A
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Murdolo, L.D, Maddumaage, J, Gras, S.
登録日2024-01-10
公開日2024-05-08
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes.
Clin Transl Immunology, 13, 2024
3MYZ
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Protein induced photophysical changes to the amyloid indicator dye, thioflavin T
分子名称: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, ACETATE ION, Beta-2-microglobulin, ...
著者Wolfe, L.S, Calabrese, M.F, Nath, A, Blaho, D.V, Miranker, A.D, Xiong, Y.
登録日2010-05-11
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Protein-induced photophysical changes to the amyloid indicator dye thioflavin T.
Proc.Natl.Acad.Sci.USA, 107, 2010
3SKO
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BU of 3sko by Molmil
Crystal structure of the HLA-B8-A66-FLR, mutant A66 of the HLA B8
分子名称: Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ...
著者Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J.
登録日2011-06-22
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.
J.Immunol., 188, 2012
4G8I
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BU of 4g8i by Molmil
Crystal Structure of HLA B2705-KK10-L6M
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, Gag protein, ...
著者Gras, S, Wilmann, P.G, Rossjohn, J.
登録日2012-07-23
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells.
Immunity, 38, 2013
3KPM
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Crystal Structure of HLA B*4402 in complex with EEYLKAWTF, a mimotope
分子名称: Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
1M6O
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BU of 1m6o by Molmil
Crystal Structure of HLA B*4402 in complex with HLA DPA*0201 peptide
分子名称: Beta-2-microglobulin, HLA DPA*0201 peptide, HLA class I histocompatibility antigen, ...
著者Macdonald, W.A, Purcell, A.W, Williams, D.S, Mifsud, N.A, Ely, L.K, Gorman, J.J, Clements, C.S, Kjer-Nielsen, L, Koelle, D.M, Brooks, A.G, Lovrecz, G.O, Lu, L, Rossjohn, J, McCluskey, J.
登録日2002-07-17
公開日2003-09-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.
J.Exp.Med., 198, 2003
7R7Y
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BU of 7r7y by Molmil
Crystal structure of HLA-B*5701 complex with an HIV-1 Gag-derived epitope QW9 S3T variant
分子名称: Beta-2-microglobulin, GLN-ALA-THR-GLN-GLU-VAL-LYS-ASN-TRP, GLYCEROL, ...
著者Li, X.L, Ng, R, Tan, K.M, Walker, B.D, Wang, J.H.
登録日2021-06-25
公開日2022-06-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Nat Commun, 14, 2023
6EI2
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BU of 6ei2 by Molmil
Crystal Structure of HLA-A68 presenting a C-terminally extended peptide
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CADMIUM ION, ...
著者Picaud, S, Guillaume, P, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gfeller, D, Filippakopoulos, P.
登録日2017-09-16
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Crystal Structure of HLA-A68 presenting a C-terminally extended peptide
To Be Published
5WMO
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Crystal Structure of HLA-B7 in complex with RPP, an EBV peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Gras, S, Rossjohn, J.
登録日2017-07-30
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
J. Immunol., 200, 2018
3V5H
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BU of 3v5h by Molmil
HLA-A2.1 KVAEIVHFL
分子名称: Beta-2-microglobulin, GLYCEROL, HIV-based altered-peptide ligand KVAEIVHFL, ...
著者Collins, E.J, Lee, H.Y.
登録日2011-12-16
公開日2012-12-05
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Prediction of immunogenicity of altered-peptide ligands for HIV therapy
To be Published
7UM2
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SARS-CoV-2 Spike-derived peptide S417-425 K417T mutant (TIADYNYKL) presented by HLA-A*02:01
分子名称: Beta-2-microglobulin, CADMIUM ION, HLA class I antigen, ...
著者Szeto, C, Gras, S.
登録日2022-04-06
公開日2023-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献SARS-CoV-2 Spike-derived peptide S417-425 K417T mutant (TIADYNYKL) presented by HLA-A*02:01
To Be Published
5C0J
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BU of 5c0j by Molmil
HLA-A02 carrying RQFGPDWIVA
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CALCIUM ION, ...
著者Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
登録日2015-06-12
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5VWH
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HLA-B*58:01 presenting LSSPVTKSW
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-21
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.648 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
6TDO
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BU of 6tdo by Molmil
Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GM dipeptide in the A pocket.
分子名称: Beta-2-microglobulin, GLYCEROL, GLYCINE, ...
著者Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R.
登録日2019-11-09
公開日2020-03-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection.
Nat Commun, 11, 2020
4WJ5
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Structure of HLA-A2 in complex with an altered peptide ligands based on Mart-1 variant epitope
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Celie, P.H.N, Rodenko, B, Ovaa, H.
登録日2014-09-29
公開日2014-10-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Altered Peptide Ligands Revisited: Vaccine Design through Chemically Modified HLA-A2-Restricted T Cell Epitopes.
J Immunol., 193, 2014
5L2J
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Crystal Structure of human CD1b in complex with C36-GMM
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-[(2R,3R)-3-hydroxy-2-tetradecyldocosanoyl]-alpha-L-idopyranose, ACETATE ION, ...
著者Gras, S, Shahine, A, Le Nours, J, Rossjohn, J.
登録日2016-08-02
公開日2016-11-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献T cell receptor recognition of CD1b presenting a mycobacterial glycolipid.
Nat Commun, 7, 2016

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