1I1F
 
 | | Crystal structure of human class i mhc (hla-a2.1) complexed with beta 2-microglobulin and hiv-rt variant peptide i1y | | 分子名称: | PROTEIN (BETA 2-MICROGLOBULIN), PROTEIN (CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-A0201 ALPHA CHAIN), ... | | 著者 | Kirksey, T.J, Pogue-Caley, R.R, Frelinger, J.A, Collins, E.J. | | 登録日 | 1999-04-16 | | 公開日 | 2000-01-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structural basis for the increased immunogenicity of two HIV-reverse transcriptase peptide variant/class I major histocompatibility complexes.
J.Biol.Chem., 274, 1999
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3AM8
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1KPR
 | | The human non-classical major histocompatibility complex molecule HLA-E | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... | | 著者 | Holmes, M.A, Strong, R.K. | | 登録日 | 2002-01-02 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
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2BCK
 | | Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Rizkallah, P.J, Jakobsen, B.K, Cole, D.K, Gao, G.F. | | 登録日 | 2005-10-19 | | 公開日 | 2006-01-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
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3U0P
 | | Crystal structure of human CD1d-lysophosphatidylcholine | | 分子名称: | (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ... | | 著者 | Lopez-Sagaseta, J, Sibener, L.V, Adams, E.J. | | 登録日 | 2011-09-28 | | 公開日 | 2012-04-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
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3GSN
 | | Crystal structure of the public RA14 TCR in complex with the HCMV dominant NLV/HLA-A2 epitope | | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, HCMV pp65 fragment 495-503 (NLVPMVATV), ... | | 著者 | Gras, S, Saulquin, X, Reiser, J.-B, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. | | 登録日 | 2009-03-27 | | 公開日 | 2009-08-04 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
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1DE4
 | | HEMOCHROMATOSIS PROTEIN HFE COMPLEXED WITH TRANSFERRIN RECEPTOR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-2-MICROGLOBULIN, CALCIUM ION, ... | | 著者 | Bennett, M.J, Lebron, J.A, Bjorkman, P.J. | | 登録日 | 1999-11-12 | | 公開日 | 2000-01-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor.
Nature, 403, 2000
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1XZ0
 | | Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(HYDROXY-HEXADECANOYL-AMINO)-2-{[(4S)-2-(2-HYDROXY-PHENYL)-4,5-DIHYDRO-OXAZOLE-4-CARBONYL]-AMINO}-HEXANOIC ACID 2-[(3S)-1-(TERT-BUTYL-DIPHENYL-SILANYLOXY)-2-OXO-AZEPAN-3-YLCARBAMOYL]-(1S)-1-METHYL-ETHYL ESTER, Beta-2-microglobulin, ... | | 著者 | Zajonc, D.M, Crispin, M.D, Bowden, T.A, Young, D.C, Cheng, T.Y, Hu, J, Costello, C.E, Miller, M.J, Moody, D.B, Wilson, I.A. | | 登録日 | 2004-11-11 | | 公開日 | 2005-03-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular Mechanism of Lipopeptide Presentation by CD1a.
Immunity, 22, 2005
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8SGB
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3JTS
 | | GY9-Mamu-A*02-hb2m | | 分子名称: | Beta-2-microglobulin, MHC class I Mamu-A*02, peptide of Gag-Pol polyprotein | | 著者 | Dai, L, Feng, Y, Qi, J, Gao, G.F. | | 登録日 | 2009-09-14 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Structure of Mamu A*2
To be Published
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3D39
 | | The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(4-fluoroPhenylalanine)) peptide | | 分子名称: | A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ... | | 著者 | Borbulevych, O.Y, Clemens, J.R, Baker, B.M. | | 登録日 | 2008-05-09 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner
Biochem.J., 423, 2009
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6EQB
 | | HLA class I histocompatibility antigen | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... | | 著者 | Rizkallah, P.J, Cole, D.K. | | 登録日 | 2017-10-12 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | TCR-induced alteration of primary MHC peptide anchor residue.
Eur.J.Immunol., 49, 2019
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5MEN
 | | Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K. | | 登録日 | 2016-11-16 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
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7N1B
 | | SARS-CoV-2 RLQ peptide binds to HLA-A2 | | 分子名称: | Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... | | 著者 | Wu, D, Mariuzza, R.A. | | 登録日 | 2021-05-27 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
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6LA7
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7RE8
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6VMC
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4PJB
 | | Structure of human MR1-5-OP-RU in complex with human MAIT B-F3-C1 TCR | | 分子名称: | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Birkinshaw, R.W, Rossjohn, J. | | 登録日 | 2014-05-12 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
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5WJN
 | | Crystal Structure of HLA-A*11:01-GTS3 | | 分子名称: | Beta-2-microglobulin, GTS3 peptide, HLA class I histocompatibility antigen, ... | | 著者 | Gras, S, Rossjohn, J. | | 登録日 | 2017-07-23 | | 公開日 | 2017-09-20 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
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1MHE
 | | THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HLA-E, PEPTIDE (VMAPRTVLL), ... | | 著者 | O'Callaghan, C.A, Tormo, J, Willcox, B.E, Braud, V.B, Jakobsen, B.K, Stuart, D.I, Mcmichael, A.J, Bell, J.I, Jones, E.Y. | | 登録日 | 1998-08-24 | | 公開日 | 1999-03-23 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Mol.Cell, 1, 1998
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5BXF
 | | Apo FcRn Structure at pH 4.5 | | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51 | | 著者 | Nam, H.-J, Taha, M. | | 登録日 | 2015-06-08 | | 公開日 | 2015-11-11 | | 実験手法 | X-RAY DIFFRACTION (2.851 Å) | | 主引用文献 | Human Fc-Receptor Neonatal at low pH gives insights into different states of FcRn
To Be Published
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8HN4
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8U9G
 | | Human Class I MHC HLA-A2 bound to sorting nexin 24 (127-135) neoantigen KLSHQLVLL | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M. | | 登録日 | 2023-09-19 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Accurate modeling of peptide-MHC structures with AlphaFold.
Structure, 32, 2024
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4LHU
 | | Crystal Structure of 9C2 TCR bound to CD1d | | 分子名称: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Uldrich, A.P, Le Nours, J, Pellicci, D.G, Gras, S, Rossjohn, J, Godfrey, D.I. | | 登録日 | 2013-07-01 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | CD1d-lipid antigen recognition by the gamma delta TCR.
Nat.Immunol., 14, 2013
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5V5M
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