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PDB: 41 件
3HCU
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BU of 3hcu by Molmil
Crystal structure of TRAF6 in complex with Ubc13 in the C2 space group
分子名称: TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION
著者Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H.
登録日2009-05-06
公開日2009-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献E2 interaction and dimerization in the crystal structure of TRAF6.
Nat.Struct.Mol.Biol., 16, 2009
7BXG
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BU of 7bxg by Molmil
MavC-UBE2N-Ub complex
分子名称: MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N
著者Gao, P, Wang, Y.
登録日2020-04-19
公開日2020-05-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
6UMP
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BU of 6ump by Molmil
Crystal structure of MavC in complex with substrate mimic in P65 space group
分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
著者Puvar, K, Iyer, S, Luo, Z.Q, Das, C.
登録日2019-10-10
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
6S53
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BU of 6s53 by Molmil
Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ...
著者Kiss, L, Boland, A, Neuhaus, D, James, L.C.
登録日2019-06-30
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Nat Commun, 10, 2019
6KL4
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BU of 6kl4 by Molmil
Crystal structure of MavC-UBE2N-Ub
分子名称: MavC, Ub, Ubiquitin-conjugating enzyme E2 N
著者Ouyang, S, Guan, H.
登録日2019-07-29
公開日2020-04-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC.
Adv Sci, 7, 2020
2C2V
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BU of 2c2v by Molmil
Crystal structure of the CHIP-UBC13-UEV1a complex
分子名称: STIP1 homology and U box-containing protein 1, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 1
著者Zhang, M, Roe, S.M, Pearl, L.H.
登録日2005-09-30
公開日2005-11-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex.
Mol. Cell, 20, 2005
6KFP
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BU of 6kfp by Molmil
Crystal structure of MavC ternary complex
分子名称: MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N
著者Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y.
登録日2019-07-08
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
3W31
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BU of 3w31 by Molmil
Structual basis for the recognition of Ubc13 by the Shigella flexneri effector OspI
分子名称: IODIDE ION, ORF169b, Ubiquitin-conjugating enzyme E2 N
著者Nishide, A, Kim, M, Takagi, K, Sasakawa, C, Mizushima, T.
登録日2012-12-07
公開日2013-03-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Structural basis for the recognition of Ubc13 by the Shigella flexneri effector OspI.
J.Mol.Biol., 425, 2013
4DHZ
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BU of 4dhz by Molmil
The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub
分子名称: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ...
著者Wiener, R, Zhang, X, Wang, T, Wolberger, C.
登録日2012-01-30
公開日2012-02-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
3VON
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BU of 3von by Molmil
Crystalstructure of the ubiquitin protease
分子名称: Ubiquitin thioesterase OTUB1, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Sato, Y, Fukai, S.
登録日2012-01-30
公開日2012-05-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13.
J.Biol.Chem., 287, 2012
5AIT
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BU of 5ait by Molmil
A complex of of RNF4-RING domain, UbeV2, Ubc13-Ub (isopeptide crosslink)
分子名称: E3 UBIQUITIN-PROTEIN LIGASE RNF4, POLYUBIQUITIN-C, UBIQUITIN-CONJUGATING ENZYME E2 N, ...
著者Branigan, E, Naismith, J.H.
登録日2015-02-17
公開日2015-07-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for the Ring Catalyzed Synthesis of K63 Linked Ubiquitin Chains
Nat.Struct.Mol.Biol., 22, 2015
5VNZ
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BU of 5vnz by Molmil
Structure of a TRAF6-Ubc13~Ub complex
分子名称: TNF receptor-associated factor 6, Ubiquitin, Ubiquitin-conjugating enzyme E2 N, ...
著者Middleton, A.J, Day, C.L.
登録日2017-05-01
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1.
Nat Commun, 8, 2017
5H7S
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BU of 5h7s by Molmil
Structural basis of the flanking zinc-finger motifs crucial for the E3 ligase activity of the LNX1 RING domain
分子名称: E3 ubiquitin-protein ligase LNX, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-like 1, ...
著者Nayak, D, Sivaraman, J.
登録日2016-11-21
公開日2017-11-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Structure of LNX1:Ubc13~Ubiquitin Complex Reveals the Role of Additional Motifs for the E3 Ligase Activity of LNX1.
J. Mol. Biol., 430, 2018
5VO0
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BU of 5vo0 by Molmil
Structure of a TRAF6-Ubc13~Ub complex
分子名称: POTASSIUM ION, TNF receptor-associated factor 6, Ubiquitin, ...
著者Middleton, A.J, Day, C.L.
登録日2017-05-01
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1.
Nat Commun, 8, 2017
4ORH
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BU of 4orh by Molmil
Crystal structure of RNF8 bound to the UBC13/MMS2 heterodimer
分子名称: E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.M.
登録日2014-02-11
公開日2014-02-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.802 Å)
主引用文献Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
4WHV
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BU of 4whv by Molmil
E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B
分子名称: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ...
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-09-23
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (8.3 Å)
主引用文献RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
J.Biol.Chem., 291, 2016
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