6VWN
 
 | | 70S ribosome bound to HIV frameshifting stem-loop (FSS) and P-site tRNA (non-rotated conformation, Structure II) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Loerch, S, Bao, C, Ling, C, Korostelev, A.A, Grigorieff, N, Ermolenko, D.M. | | 登録日 | 2020-02-20 | | 公開日 | 2020-06-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.
Elife, 9, 2020
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5O2R
 | | Cryo-EM structure of the proline-rich antimicrobial peptide Api137 bound to the terminating ribosome | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Graf, M, Berninghausen, O, Beckmann, R, Wilson, D.N. | | 登録日 | 2017-05-22 | | 公開日 | 2017-07-26 | | 最終更新日 | 2019-02-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.
Nat. Struct. Mol. Biol., 24, 2017
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6VWM
 | | 70S ribosome bound to HIV frameshifting stem-loop (FSS) and P-site tRNA (non-rotated conformation, Structure I) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Loerch, S, Bao, C, Ling, C, Korostelev, A.A, Grigorieff, N, Ermolenko, D.M. | | 登録日 | 2020-02-20 | | 公開日 | 2020-06-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.
Elife, 9, 2020
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5LZD
 | | Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H. | | 登録日 | 2016-09-29 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
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8A3L
 | | Structural insights into the binding of bS1 to the ribosome | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... | | 著者 | D'Urso, G, Chat, S, Gillet, R, Giudice, E. | | 登録日 | 2022-06-08 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Structural insights into the binding of bS1 to the ribosome.
Nucleic Acids Res., 51, 2023
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7ACR
 | | Structure of post-translocated trans-translation complex on E. coli stalled ribosome. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | | 登録日 | 2020-09-11 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome.
Nat Commun, 12, 2021
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4V4Q
 | | Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D. | | 登録日 | 2005-08-30 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | Structures of the bacterial ribosome at 3.5 A resolution.
Science, 310, 2005
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4V4H
 | | Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic kasugamyin at 3.5A resolution. | | 分子名称: | (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, ... | | 著者 | Schuwirth, B.S, Vila-Sanjurjo, A, Cate, J.H.D. | | 登録日 | 2006-08-04 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | Structural analysis of kasugamycin inhibition of translation.
Nat.Struct.Mol.Biol., 13, 2006
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4V57
 | | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin. | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D. | | 登録日 | 2007-07-21 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
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4V64
 | | Crystal structure of the bacterial ribosome from Escherichia coli in complex with hygromycin B. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Borovinskaya, M.A, Shoji, S, Fredrick, K, Cate, J.H.D. | | 登録日 | 2008-06-11 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis for hygromycin B inhibition of protein biosynthesis
Rna, 14, 2008
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6WNV
 | | 70S ribosome without free 5S rRNA and with a perturbed PTC | | 分子名称: | 16S ribosomal RNA, 23s-5s joint ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Loveland, A.B, Korostelev, A.A, Mankin, A.S, Huang, S, Aleksashin, N.A, Klepacki, D, Reier, K, Kefi, A, Szal, A, Remme, J, Jaeger, L, Vazquez-Laslop, N. | | 登録日 | 2020-04-23 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly.
Nat Commun, 11, 2020
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6X7F
 | | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B2 (TTC-B2) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | | 登録日 | 2020-05-29 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-09-23 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of transcription-translation coupling.
Science, 369, 2020
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6ORL
 | | RF1 pre-accommodated 70S complex at 24 ms | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | 登録日 | 2019-04-30 | | 公開日 | 2019-06-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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7BL3
 | | pre-50S-ObgE particle state 2 | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | 著者 | Hilal, T, Nikolay, R, Spahn, C.M.T. | | 登録日 | 2021-01-18 | | 公開日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
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6OSQ
 | | RF1 accommodated state bound Release complex 70S at long incubation time point | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | 登録日 | 2019-05-02 | | 公開日 | 2019-06-26 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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7JT2
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6ZTL
 | | E. coli 70S-RNAP expressome complex in collided state bound to NusG | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | | 登録日 | 2020-07-20 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
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7K51
 | | Mid-translocated non-frameshifting(CCA-A) complex with EF-G and GDPCP (Structure II) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A. | | 登録日 | 2020-09-16 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
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7NSP
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7OJ0
 | | Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2 | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | | 登録日 | 2021-05-13 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021
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5LZE
 | | Structure of the 70S ribosome with Sec-tRNASec in the classical pre-translocation state (C) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H. | | 登録日 | 2016-09-29 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
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6BU8
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5U4I
 | | Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H. | | 登録日 | 2016-12-04 | | 公開日 | 2017-01-11 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
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4V53
 | | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin. | | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ... | | 著者 | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | | 登録日 | 2007-06-16 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.54 Å) | | 主引用文献 | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
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5JTE
 | | Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Arenz, S, Bock, L.V, Graf, M, Innis, C.A, Beckmann, R, Grubmueller, H, Vaiana, A.C, Wilson, D.N. | | 登録日 | 2016-05-09 | | 公開日 | 2016-07-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.
Nat Commun, 7, 2016
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