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PDB: 35 件
6HXM
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BU of 6hxm by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221
分子名称: ATP-citrate synthase, CITRATE ANION, COENZYME A
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXL
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BU of 6hxl by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH (space group P21)
分子名称: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
5TDE
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BU of 5tde by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate
分子名称: ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
6Z2H
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BU of 6z2h by Molmil
Citryl-CoA lyase module of human ATP citrate lyase in complex with (3S)-citryl-CoA.
分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ATP-citrate synthase, ...
著者Verschueren, K.H.G, Verstraete, K.
登録日2020-05-15
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
5TDF
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BU of 5tdf by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4S hydroxycitrate
分子名称: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ADENINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
6HXK
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BU of 6hxk by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate
分子名称: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
5TDZ
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BU of 5tdz by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Tartrate and ADP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-20
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
3MWD
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BU of 3mwd by Molmil
Truncated Human ATP-Citrate Lyase with Citrate Bound
分子名称: ATP-citrate synthase, CITRIC ACID
著者Fraser, M.E, Sun, T.
登録日2010-05-05
公開日2010-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography.
J.Biol.Chem., 285, 2010
5TDM
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BU of 5tdm by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate and ADP
分子名称: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
7RIG
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BU of 7rig by Molmil
Structure of ACLY-D1026A-substrates
分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Wei, X, Marmorstein, R.
登録日2021-07-19
公開日2023-05-10
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
3MWE
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BU of 3mwe by Molmil
Truncated Human ATP-Citrate Lyase with Tartrate Bound
分子名称: ATP-citrate synthase, L(+)-TARTARIC ACID, MAGNESIUM ION
著者Fraser, M.E, Sun, T.
登録日2010-05-05
公開日2010-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography.
J.Biol.Chem., 285, 2010
8G5C
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BU of 8g5c by Molmil
Structure of ACLY-D1026A-substrates, local refinement of ASH domain
分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Xuepeng, W, Ronen, M.
登録日2023-02-12
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
5TET
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BU of 5tet by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4S Hydroxycitrate
分子名称: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ATP-citrate synthase, GLYCEROL, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-22
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TE1
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BU of 5te1 by Molmil
C20S, C293G Mutant N-terminal Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate
分子名称: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ATP-citrate synthase, PHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-20
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
3PFF
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BU of 3pff by Molmil
Truncated human atp-citrate lyase with ADP and tartrate bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, L(+)-TARTARIC ACID, ...
著者Fraser, M.E, Sun, T.
登録日2010-10-28
公開日2011-10-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献ADP-Mg2+ bound to the ATP-grasp domain of ATP-citrate lyase.
Acta Crystallogr.,Sect.F, 67, 2011
5TEQ
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BU of 5teq by Molmil
C20S C293G MUTANT N-TERMINAL HUMAN ATP CITRATE LYASE BOUND TO CITRATE
分子名称: ATP-citrate synthase, CITRATE ANION, PHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-22
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
8G1F
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BU of 8g1f by Molmil
Structure of ACLY-D1026A-products
分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wei, X, Marmorstein, R.
登録日2023-02-02
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
5TES
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BU of 5tes by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-22
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
8G5D
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BU of 8g5d by Molmil
Structure of ACLY-D1026A-products, local refinement of ASH domain
分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wei, X, Marmorstein, R.
登録日2023-02-13
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
7RKZ
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BU of 7rkz by Molmil
Structure of ACLY D1026A-substrates-asym-int
分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Wei, X, Marmorstein, R.
登録日2021-07-22
公開日2023-05-10
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
7RMP
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BU of 7rmp by Molmil
Structure of ACLY D1026A - substrates-asym
分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Wei, X, Marmorstein, R.
登録日2021-07-28
公開日2023-05-10
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
8G1E
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BU of 8g1e by Molmil
Structure of ACLY-D1026A-products-asym
分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wei, X, Marmorstein, R.
登録日2023-02-02
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
7LIW
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BU of 7liw by Molmil
Local refinement of human ATP citrate lyase E599Q mutant ASH domain
分子名称: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Wei, X, Marmorstein, R.
登録日2021-01-28
公開日2021-05-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
6UUW
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BU of 6uuw by Molmil
Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA
分子名称: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Wei, X, Marmorstein, R.
登録日2019-11-01
公開日2019-12-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Molecular basis for acetyl-CoA production by ATP-citrate lyase
Nat.Struct.Mol.Biol., 27, 2020
7LLA
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BU of 7lla by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate (EM map was generated in Cryosparc with non-uniform refinement)
分子名称: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
著者Wei, X, Marmorstein, R.
登録日2021-02-03
公開日2021-03-03
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021

 

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