4U4N
 
 | | Crystal structure of Edeine bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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4U4Z
 | | Crystal structure of Phyllanthoside bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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4U6F
 | | Crystal structure of T-2 toxin bound to the yeast 80S ribosome | | 分子名称: | 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate, 18S ribosomal RNA, 25S ribosomal RNA, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-28 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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6T7T
 | | Structure of yeast 80S ribosome stalled on poly(A) tract. | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | | 登録日 | 2019-10-23 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
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6Q8Y
 | | Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Tesina, P, Heckel, E, Cheng, J, Buschauer, R, Kater, L, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2018-12-16 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the 80S ribosome-Xrn1 nuclease complex.
Nat.Struct.Mol.Biol., 26, 2019
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6TNU
 | | Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs. | | 分子名称: | 18S rRNA, 25S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | 著者 | Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R. | | 登録日 | 2019-12-10 | | 公開日 | 2020-04-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
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5FCJ
 | | Structure of the anisomycin-containing uL3 W255C mutant 80S yeast ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M. | | 登録日 | 2015-12-15 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016
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5I4L
 | | Crystal structure of Amicoumacin A bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Prokhorova, I.V, Yusupova, G, Yusupov, M. | | 登録日 | 2016-02-12 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome.
Sci Rep, 6, 2016
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5DGV
 | | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog | | 分子名称: | 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | | 登録日 | 2015-08-28 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
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6HHQ
 | | Crystal structure of compound C45 bound to the yeast 80S ribosome | | 分子名称: | (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | | 著者 | Pellegrino, S, Vanderwal, C.D, Yusupov, M. | | 登録日 | 2018-08-28 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.10000038 Å) | | 主引用文献 | Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Nucleic Acids Res., 47, 2019
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5ON6
 | | Crystal structure of haemanthamine bound to the 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Pellegrino, S, Meyer, M, Yusupova, G, Yusupov, M. | | 登録日 | 2017-08-03 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.10000229 Å) | | 主引用文献 | The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth.
Structure, 26, 2018
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8UTI
 | | Eukaryotic 80S ribosome with Reh1 and A/P site tRNA | | 分子名称: | 18S rRNA, 25S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | 著者 | Yelland, J.N, Taylor, D.W, Johnson, A.W. | | 登録日 | 2023-10-31 | | 公開日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | The Ribosome Assembly Factor Reh1 is Released from the Polypeptide Exit Tunnel in the Pioneer Round of Translation
To Be Published
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5DAT
 | | Complex of yeast 80S ribosome with hypusine-containing eIF5A | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | | 登録日 | 2015-08-20 | | 公開日 | 2016-08-31 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
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8P4V
 | | 80S yeast ribosome in complex with HaterumaimideQ | | 分子名称: | (3~{R})-3-[(1~{S})-2-[(1~{R},3~{S},4~{a}~{S},8~{a}~{S})-5,5,8~{a}-trimethyl-2-methylidene-3-oxidanyl-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | | 著者 | Terrosu, S, Yusupov, M. | | 登録日 | 2023-05-23 | | 公開日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | | 主引用文献 | Role of Protein eL42 in the Ribosome Binding of Synthetic Analogues of Natural Lissoclimides
To Be Published
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4U51
 | | Crystal structure of Narciclasine bound to the yeast 80S ribosome | | 分子名称: | (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one, 18S ribosomal RNA, 25S ribosomal RNA, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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4U3N
 | | Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-22 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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4U55
 | | Crystal structure of Cryptopleurine bound to the yeast 80S ribosome | | 分子名称: | (14aR)-2,3,6-trimethoxy-11,12,13,14,14a,15-hexahydro-9H-dibenzo[f,h]pyrido[1,2-b]isoquinoline, 18S ribosomal RNA, 25S ribosomal RNA, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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8K2D
 | | Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A | | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | | 登録日 | 2023-07-12 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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6T7I
 | | Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | | 登録日 | 2019-10-22 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
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4U50
 | | Crystal structure of Verrucarin bound to the yeast 80S ribosome | | 分子名称: | (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione, 18S ribosomal RNA, 25S ribosomal RNA, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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4U4Y
 | | Crystal structure of Pactamycin bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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8UT0
 | | Eukaryotic 80S ribosome with Reh1, eIF5A and A/P site tRNA | | 分子名称: | 18S rRNA, 25S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | 著者 | Yelland, J.N, Taylor, D.W, Johnson, A.W. | | 登録日 | 2023-10-30 | | 公開日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | The Ribosome Assembly Factor Reh1 is Released from the Polypeptide Exit Tunnel in the Pioneer Round of Translation
To Be Published
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5DC3
 | | Complex of yeast 80S ribosome with non-modified eIF5A | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | | 登録日 | 2015-08-23 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome.
J.Mol.Biol., 428, 2016
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5LYB
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6S47
 | | Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1 | | 分子名称: | 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V. | | 登録日 | 2019-06-26 | | 公開日 | 2019-07-24 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling.
Nucleic Acids Res., 47, 2019
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