1W79
 
 | | Crystal structure of the DD-transpeptidase-carboxypeptidase from Actinomadura R39 | | 分子名称: | D-alanyl-D-alanine carboxypeptidase, MAGNESIUM ION, SULFATE ION | | 著者 | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | | 登録日 | 2004-08-31 | | 公開日 | 2005-06-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins.
J. Biol. Chem., 280, 2005
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3ZVW
 | | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,3-DIMETHYLBUTAN-1-OL, ACETONE, ... | | 著者 | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2011-07-28 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
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4BEN
 | | R39-imipenem Acyl-enzyme crystal structure | | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, ... | | 著者 | Van Elder, D, Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2013-03-11 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal Structures of R39-Imipenem Acyl-Enzyme.
To be Published
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2WKE
 | | Crystal structure of the Actinomadura R39 DD-peptidase inhibited by 6- beta-iodopenicillanate. | | 分子名称: | (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, ... | | 著者 | Sauvage, E, Herman, R, Kerff, F, Charlier, P. | | 登録日 | 2009-06-10 | | 公開日 | 2009-12-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate.
J.Am.Chem.Soc., 131, 2009
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4B4Z
 | | Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor | | 分子名称: | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Cannella, S.E, Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2012-08-02 | | 公開日 | 2013-08-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of a Complex between Actinomadura R39 Dd-Peptidase and a Boronate Inhibitor
To be Published
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2VGK
 | | Crystal structure of Actinomadura R39 DD-peptidase complexed with a peptidoglycan-mimetic cephalosporin | | 分子名称: | (2R)-2-AMINO-7-{[(1R)-1-CARBOXYETHYL]AMINO}-7-OXOHEPTANOIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... | | 著者 | Sauvage, E, kerff, F, Herman, R, Charlier, P. | | 登録日 | 2007-11-14 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structures of Complexes of Bacterial Dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle.
J.Mol.Biol., 381, 2008
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2XDM
 | | Crystal structure of a complex between Actinomadura R39 DD peptidase and a peptidoglycan mimetic boronate inhibitor | | 分子名称: | (D-ALPHA-AMINOPIMELYLAMINO)-D-1-ETHYLBORONIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COBALT (II) ION, ... | | 著者 | Rocaboy, M, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | | 登録日 | 2010-05-04 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of a Complex between the Actinomadura R39 Dd-Peptidase and a Peptidoglycan- Mimetic Boronate Inhibitor: Interpretation of a Transition State Analogue in Terms of Catalytic Mechanism.
Biochemistry, 49, 2010
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1W8Y
 | | Crystal structure of the nitrocefin acyl-DD-peptidase from Actinomadura R39. | | 分子名称: | (2R)-2-{(1R)-2-OXO-1-[(2-THIENYLACETYL)AMINO]ETHYL}-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC ACID, D-alanyl-D-alanine carboxypeptidase, MAGNESIUM ION, ... | | 著者 | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | | 登録日 | 2004-10-01 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of the Actinomadura R39 Dd- Peptidase Reveals New Domains in Penicillin- Binding Proteins.
J.Biol.Chem., 280, 2005
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2XLN
 | | Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor | | 分子名称: | COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE,, SULFATE ION, ... | | 著者 | Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2010-07-21 | | 公開日 | 2011-01-26 | | 最終更新日 | 2014-06-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors
Acs Med.Chem.Lett., 2, 2011
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2VGJ
 | | Crystal structure of Actinomadura R39 DD-peptidase complexed with a peptidoglycan-mimetic cephalosporin | | 分子名称: | CEPHALOSPORIN, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... | | 著者 | Sauvage, E, kerff, F, Herman, R, Charlier, P. | | 登録日 | 2007-11-14 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of Complexes of Bacterial Dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle.
J.Mol.Biol., 381, 2008
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2Y59
 | | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | | 分子名称: | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2011-01-12 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
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2Y55
 | | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | | 分子名称: | ACETONE, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... | | 著者 | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2011-01-12 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
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3ZCZ
 | | Crystal structure of a complex between Actinomadura R39 DD-peptidase and a trifluoroketone inhibitor | | 分子名称: | (2R)-2-amino-7-oxo-7-{[(2R,3S)-4,4,4-trifluoro-3-hydroxybutan-2-yl]amino}heptanoic acid, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... | | 著者 | Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2012-11-23 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Inhibition of Dd-Peptidases by a Specific Trifluoroketone: Crystal Structure of a Complex with the Actinomadura R39 Dd-Peptidase.
Biochemistry, 52, 2013
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4B4X
 | | Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor | | 分子名称: | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Cannella, S.E, Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2012-08-01 | | 公開日 | 2013-08-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structure of a Complex between Actinomadura R39 Dd-Peptidase and a Boronate Inhibitor
To be Published
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2Y4A
 | | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | | 分子名称: | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2011-01-05 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
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2XK1
 | | Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor | | 分子名称: | COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION, ... | | 著者 | Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2010-07-07 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors
Acs Med.Chem.Lett., 2, 2011
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1W8Q
 | | Crystal Structure of the DD-Transpeptidase-carboxypeptidase from Actinomadura R39 | | 分子名称: | COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION | | 著者 | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | | 登録日 | 2004-09-24 | | 公開日 | 2005-06-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal Structure of the Actinomadura R39 Dd-Peptidase Reveals New Domains in Penicillin-Binding Proteins.
J.Biol.Chem., 280, 2005
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3ZVT
 | | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | | 分子名称: | 2,6 DIMETHOXYBENZAMIDOBORONIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... | | 著者 | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2011-07-27 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
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