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PDB: 17 件
3I84
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The Crystal Structure of Human EMMPRIN N-terminal Domain 1 in P6(1)22 space group
分子名称: CHLORIDE ION, Cervical EMMPRIN
著者Luo, J, Gilliland, G.L.
登録日2009-07-09
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the EMMPRIN N-terminal domain 1: Dimerization via beta-strand swapping.
Proteins, 77, 2009
7XY8
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Crystal structure of antibody Fab fragment in complex with CD147(EMMPIRIN)
分子名称: Isoform 2 of Basigin, heavy chain, light chain
著者Nakamura, K, Amano, M, Yoneda, K, Suzuki, M, Fukuchi, K.
登録日2022-06-01
公開日2022-11-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals.
J Oncol, 2022, 2022
3QR2
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Wild type CD147 Ig0 domain
分子名称: Basigin
著者Redzic, J.S, Armstrong, G.S, Isern, N.G, Kieft, J.S, Eisenmesser, E.Z, Berkeley Structural Genomics Center (BSGC)
登録日2011-02-16
公開日2011-05-11
最終更新日2011-08-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Retinal Specific CD147 Ig0 Domain: From Molecular Structure to Biological Activity.
J.Mol.Biol., 411, 2011
3QQN
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The retinal specific CD147 Ig0 domain: from molecular structure to biological activity
分子名称: Basigin
著者Redzic, J.S, Armstrong, G.S, Isern, N.G, Kieft, J.S, Eisenmesser, E.Z, Berkeley Structural Genomics Center (BSGC)
登録日2011-02-15
公開日2011-05-11
最終更新日2011-08-17
実験手法X-RAY DIFFRACTION (2.309 Å)
主引用文献The Retinal Specific CD147 Ig0 Domain: From Molecular Structure to Biological Activity.
J.Mol.Biol., 411, 2011
5X0T
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Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody 6H8
分子名称: 6H8 Fab fragment heavy chain, 6H8 Fab fragment light chain, Basigin
著者Lin, P, Zhang, M.-Y, Ye, S, Chen, X, Yu, X.-L, Zhang, R.-G, Zhu, P, Chen, Z.-N.
登録日2017-01-23
公開日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody
To Be Published
3I85
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The Crystal Structure of Human EMMPRIN N-terminal Domain 1
分子名称: Cervical EMMPRIN
著者Luo, J, Gilliland, G.L.
登録日2009-07-09
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the EMMPRIN N-terminal domain 1: Dimerization via beta-strand swapping.
Proteins, 77, 2009
7DAA
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Crystal structure of basigin complexed with anti-basigin Fab fragment
分子名称: CADMIUM ION, Heavy chain of antibody Fab fragment, Isoform 2 of Basigin, ...
著者Sakuragi, T, Kanai, R, Narita, H, Onishi, E, Miyazaki, T, Baba, T, Nakagawa, A, Toyoshima, C, Nagata, S.
登録日2020-10-16
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes.
Nat.Struct.Mol.Biol., 28, 2021
3B5H
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Crystal structure of the extracellular portion of HAb18G/CD147
分子名称: ACETATE ION, Cervical EMMPRIN
著者Yu, X.-L, Chen, Z.-N.
登録日2007-10-26
公開日2008-05-06
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion.
J.Biol.Chem., 283, 2008
7CKO
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Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate 7ACC2 in the inward-open conformation
分子名称: 7-[methyl-(phenylmethyl)amino]-2-oxidanylidene-chromene-3-carboxylic acid, Basigin, Monocarboxylate transporter 1
著者Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C.
登録日2020-07-18
公開日2020-12-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
7CKR
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Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate BAY-8002 in the outward-open conformation.
分子名称: 2-[[2-chloranyl-5-(phenylsulfonyl)phenyl]carbonylamino]benzoic acid, Basigin, Monocarboxylate transporter 1
著者Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C.
登録日2020-07-18
公開日2020-12-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
4U0Q
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Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to basigin
分子名称: Basigin, Reticulocyte binding protein 5
著者Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K.
登録日2014-07-14
公開日2014-08-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
Nature, 515, 2014
6LYY
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Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate AZD3965 in the outward-open conformation.
分子名称: 3-methyl-5-[[(4~{R})-4-methyl-4-oxidanyl-1,2-oxazolidin-2-yl]carbonyl]-6-[[5-methyl-3-(trifluoromethyl)-1~{H}-pyrazol-4-yl]methyl]-1-propan-2-yl-thieno[2,3-d]pyrimidine-2,4-dione, Basigin, Monocarboxylate transporter 1
著者Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C.
登録日2020-02-16
公開日2020-12-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
6LZ0
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Cryo-EM structure of human MCT1 in complex with Basigin-2 in the presence of lactate
分子名称: (2S)-2-HYDROXYPROPANOIC ACID, Basigin, Monocarboxylate transporter 1
著者Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C.
登録日2020-02-16
公開日2020-12-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
7DA5
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Cryo-EM structure of the human MCT1 D309N mutant in complex with Basigin-2 in the inward-open conformation.
分子名称: Basigin, Monocarboxylate transporter 1
著者Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C.
登録日2020-10-14
公開日2020-12-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
8XEJ
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Cryo-EM structure of human XKR8-basigin complex in lipid nanodisc
分子名称: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Fab heavy chain, Fab light chain, ...
著者Sakuragi, T.S, Kanai, R.K, Kikkawa, M.K, Toyoshima, C.T, Nagata, S.N.
登録日2023-12-12
公開日2024-02-28
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase.
J.Biol.Chem., 300, 2024
7DCE
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Cryo-EM structure of human XKR8-basigin complex bound to Fab fragment
分子名称: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Heavy chain of Fab fragment, Isoform 2 of Basigin, ...
著者Sakuragi, T, Kanai, R, Tsutsumi, A, Narita, H, Onishi, E, Miyazaki, T, Baba, T, Nakagawa, A, Kikkawa, M, Toyoshima, C, Nagata, S.
登録日2020-10-26
公開日2021-10-20
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes.
Nat.Struct.Mol.Biol., 28, 2021
5XF0
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Solution structure of the IgI domain of CD147
分子名称: Basigin
著者Jin, S.J, Xia, B.
登録日2017-04-06
公開日2018-04-11
実験手法SOLUTION NMR
主引用文献Zn(II) can mediate self-association of the extracellular C-terminal domain of CD147
Protein Cell, 9, 2018

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件を2024-07-10に公開中

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