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PDB: 228 件
7RZD
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BU of 7rzd by Molmil
CRYSTAL STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PEPTIDE
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
著者Patskovsky, Y, Patskovska, L, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M.
登録日2021-08-27
公開日2022-11-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
5WMN
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BU of 5wmn by Molmil
Crystal Structure of HLA-B7 in complex with SPI, an influenza peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Gras, S, Rossjohn, J.
登録日2017-07-30
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
J. Immunol., 200, 2018
5DEG
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BU of 5deg by Molmil
Crystal structure of B*27:06 bound to the pVIPR peptide
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Loll, B, Fabian, H, Hee, C.S, Huser, H, Uchanska-Ziegler, B, Ziegler, A.
登録日2015-08-25
公開日2015-11-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis.
Arthritis Rheumatol, 68, 2016
6D2R
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BU of 6d2r by Molmil
HLA-B*57:01 presenting GSFDYSGVHLW
分子名称: Beta-2-microglobulin, GLY-SER-PHE-ASP-TYR-SER-GLY-VAL-HIS-LEU-TRP, HLA class I histocompatibility antigen, ...
著者Vivian, J.P, Rossjohn, J.
登録日2018-04-13
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.
Sci Immunol, 3, 2018
3KPQ
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BU of 3kpq by Molmil
Crystal Structure of HLA B*4405 in complex with EEYLKAWTF, a mimotope
分子名称: Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3VFS
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BU of 3vfs by Molmil
crystal structure of HLA B*3508LPEP-P5Ala , peptide mutant P5-ala
分子名称: Beta-2-microglobulin, LPEP peptide from EBV, P5A, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
3BP4
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BU of 3bp4 by Molmil
The high resolution crystal structure of HLA-B*2705 in complex with a Cathepsin A signal sequence peptide pCatA
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Kumar, P, Vahedi-Faridi, A, Saenger, W, Uchanska-Ziegler, B, Ziegler, A.
登録日2007-12-18
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
J.Biol.Chem., 284, 2009
5EO1
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BU of 5eo1 by Molmil
Crystal Structure of HLA-B0702-RL9
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Josephs, T.M, Gras, S, Rossjohn, J.
登録日2015-11-10
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.
J Immunol., 196, 2016
3B3I
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BU of 3b3i by Molmil
Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Beltrami, A, Rossmann, M, Fiorillo, M.T, Paladini, F, Sorrentino, R, Saenger, W, Kumar, P, Ziegler, A, Uchanska-Ziegler, B.
登録日2007-10-22
公開日2008-07-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes.
J.Biol.Chem., 283, 2008
3C9N
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BU of 3c9n by Molmil
Crystal Structure of a SARS Corona Virus Derived Peptide Bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Roder, G.A, Kristensen, O, Kastrup, J.S, Buus, S, Gajhede, M.
登録日2008-02-18
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501.
ACTA CRYSTALLOGR.,SECT.F, 64, 2008
7S7F
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BU of 7s7f by Molmil
STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH DOT1L(998-1006) PHOSPHOPEPTIDE
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M.
登録日2021-09-15
公開日2022-11-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
6D29
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BU of 6d29 by Molmil
HLA-B*57:01 presenting TSMSFVPRPW
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Vivian, J.P, Rossjohn, J.
登録日2018-04-13
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.
Sci Immunol, 3, 2018
6BJ3
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BU of 6bj3 by Molmil
TCR55 in complex with HIV(Pol448-456)/HLA-B35
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HIV Pol B35 peptide, ...
著者Jude, K.M, Sibener, L.V, Garcia, K.C.
登録日2017-11-03
公開日2018-07-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
Cell, 174, 2018
4G9F
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BU of 4g9f by Molmil
Crystal Structure of C12C TCR-HLAB2705-KK10-L6M
分子名称: Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen, ...
著者Gras, S, Wilmann, P.G, Rossjohn, J.
登録日2012-07-23
公開日2013-03-20
最終更新日2020-04-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells.
Immunity, 38, 2013
3LKS
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BU of 3lks by Molmil
Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1980 strain
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
登録日2010-01-27
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LN5
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BU of 3ln5 by Molmil
Crystal structure of HLA-B*4104 in complex with a 11mer self-peptide derived from S-methyl-5-thioadenosine phosphorylase
分子名称: 11-mer peptide from S-methyl-5'-thioadenosine phosphorylase, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Theodossis, A, Gras, S, Rossjohn, J.
登録日2010-02-02
公開日2010-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
3VRJ
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BU of 3vrj by Molmil
HLA-B*57:01-LTTKLTNTNI in complex with abacavir
分子名称: 10-mer peptide, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Vivian, J.P, Illing, P.T, McCluskey, J, Rossjohn, J.
登録日2012-04-11
公開日2012-05-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
Nature, 486, 2012
5T6W
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BU of 5t6w by Molmil
HLA-B*57:01 presenting SSTRGISQLW
分子名称: Beta-2-microglobulin, Decapeptide: SER-SER-THR-ARG-GLY-ILE-SER-GLN-LEU-TRP, GLYCEROL, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2016-09-01
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
4JQX
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BU of 4jqx by Molmil
HLA-B*44:03 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 169-180)
分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
著者Theodossis, A, Welland, A, Gras, S, Rossjohn, J.
登録日2013-03-20
公開日2013-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献HLA Peptide Length Preferences Control CD8+ T Cell Responses.
J.Immunol., 191, 2013
6UJ7
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BU of 6uj7 by Molmil
Crystal structure of HLA-B*07:02 with R140Q mutant IDH2 peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Miller, M.S, Thirawatananond, P, Gabelli, S.B.
登録日2019-10-02
公開日2021-05-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Nat Commun, 12, 2021
7LFZ
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BU of 7lfz by Molmil
Human leukocyte antigen B*07:02 in complex with SARS-CoV2 epitope IPRRNVATL
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Patskovska, L, Patskovsky, Y, Krogsgaard, M.
登録日2021-01-19
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Human leukocyte antigen B*07:02 in complex with SARS-CoV2 epitope IPRRNVATL
To Be Published
3KPP
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BU of 3kpp by Molmil
Crystal Structure of HLA B*4405 in complex with EEYLQAFTY a self peptide from the ABCD3 protein
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, EEYLQAFTY, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
5VUF
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BU of 5vuf by Molmil
HLA-B*57:01 presenting LTVQVARVY
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-19
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
6D2T
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BU of 6d2t by Molmil
HLA-B*57:01 presenting LALLTGVRW
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Vivian, J.P, Rossjohn, J.
登録日2018-04-13
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.
Sci Immunol, 3, 2018
1JGD
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BU of 1jgd by Molmil
HLA-B*2709 bound to deca-peptide s10R
分子名称: BETA-2-MICROGLOBULIN, GLYCEROL, HUMAN LYMPHOCYTE ANTIGEN HLA-B27, ...
著者Hillig, R.C, Huelsmeyer, M, Saenger, W, Volz, A, Uchanska-Ziegler, B, Ziegler, A.
登録日2001-06-25
公開日2003-07-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Thermodynamic and structural analysis of peptide- and allele-dependent properties of two HLA-B27 subtypes exhibiting differential disease association
J.Biol.Chem., 279, 2004

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