2A7Q
| Crystal structure of human dCK complexed with clofarabine and ADP | 分子名称: | 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, ... | 著者 | Zhang, Y, Secrist III, J.A, Ealick, S.E. | 登録日 | 2005-07-05 | 公開日 | 2006-01-24 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation. Acta Crystallogr.,Sect.D, 62, 2006
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2A30
| Crystal structure of human deoxycytidine kinase in complex with deoxycytidine | 分子名称: | 2'-DEOXYCYTIDINE, CALCIUM ION, Deoxycytidine kinase | 著者 | Godsey, M.H, Ort, S, Sabini, E, Konrad, M, Lavie, A. | 登録日 | 2005-06-23 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization. Biochemistry, 45, 2006
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2A2Z
| Crystal Structure of human deoxycytidine kinase in complex with deoxycytidine and uridine diphosphate | 分子名称: | 2'-DEOXYCYTIDINE, CALCIUM ION, Deoxycytidine kinase, ... | 著者 | Godsey, M.H, Ort, S, Sabini, E, Konrad, M, Lavie, A. | 登録日 | 2005-06-23 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization. Biochemistry, 45, 2006
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5MQT
| Crystal structure of dCK mutant C3S in complex with imatinib and UDP | 分子名称: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Deoxycytidine kinase, ... | 著者 | Saez-Ayala, M, Rebuffet, E, Hammam, K, Gros, L, Lopez, S, Hajem, B, Humbert, M, Baudelet, E, Audebert, S, Betzi, S, Lugari, A, Combes, S, Pez, D, Letard, S, Mansfield, C, Moussy, A, de Sepulveda, P, Morelli, X, Dubreuil, P. | 登録日 | 2016-12-20 | 公開日 | 2017-11-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology. Nat Commun, 8, 2017
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5MQL
| Crystal structure of dCK mutant C3S in complex with masitinib and UDP | 分子名称: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ... | 著者 | Rebuffet, E, Hammam, K, Saez-Ayala, M, Gros, L, Lopez, S, Hajem, B, Humbert, M, Baudelet, E, Audebert, S, Betzi, S, Lugari, A, Combes, S, Pez, D, Letard, S, Mansfield, C, Moussy, A, de Sepulveda, P, Morelli, X, Dubreuil, P. | 登録日 | 2016-12-20 | 公開日 | 2017-11-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology. Nat Commun, 8, 2017
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2QRN
| Human Deoxycytidine kinase dCMP, UDP, Mg ion product complex | 分子名称: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ... | 著者 | Ealick, S.E, Soriano, E.V. | 登録日 | 2007-07-28 | 公開日 | 2007-12-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structures of human deoxycytidine kinase product complexes. Acta Crystallogr.,Sect.D, 63, 2007
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2QRO
| Human Deoxycytidine kinase dAMP, UDP, Mg ion product complex | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ... | 著者 | Ealick, S.E, Soriano, E.V. | 登録日 | 2007-07-28 | 公開日 | 2007-12-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Structures of human deoxycytidine kinase product complexes. Acta Crystallogr.,Sect.D, 63, 2007
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5MQJ
| Crystal structure of dCK mutant C3S | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ... | 著者 | Saez-Ayala, M, Rebuffet, E, Hammam, K, Gros, L, Lopez, S, Hajem, B, Humbert, M, Baudelet, E, Audebert, S, Betzi, S, Lugari, A, Combes, S, Pez, D, Letard, S, Mansfield, C, Moussy, A, de Sepulveda, P, Morelli, X, Dubreuil, P. | 登録日 | 2016-12-20 | 公開日 | 2017-11-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology. Nat Commun, 8, 2017
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