5ZV3
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6BB4
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8Q8R
| Tau - AD-PHF | 分子名称: | Isoform Tau-D of Microtubule-associated protein tau | 著者 | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | 登録日 | 2023-08-18 | 公開日 | 2023-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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8OTG
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8Q9H
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8Q2L
| Tau - AD-MIA4 | 分子名称: | Isoform Tau-D of Microtubule-associated protein tau | 著者 | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | 登録日 | 2023-08-02 | 公開日 | 2023-09-20 | 最終更新日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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7P6B
| Limbic-predominant neuronal inclusion body 4R tauopathy type 1b tau filament | 分子名称: | Microtubule-associated protein tau | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | 登録日 | 2021-07-15 | 公開日 | 2021-09-15 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Structure-based classification of tauopathies. Nature, 598, 2021
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8Q2J
| Tau - AD-MIA2 | 分子名称: | Isoform Tau-D of Microtubule-associated protein tau | 著者 | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | 登録日 | 2023-08-02 | 公開日 | 2023-08-30 | 最終更新日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (2.23 Å) | 主引用文献 | Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
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7QK6
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8CAQ
| Structure of Tau filaments Type I from Subacute Sclerosing Panencephalitis | 分子名称: | Microtubule-associated protein tau | 著者 | Qi, C, Hasegawa, M, Takao, M, Sakai, M, Akagi, M, Iwasaki, Y, Yoshida, M, Scheres, S.H.W, Goedert, M. | 登録日 | 2023-01-24 | 公開日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy. Acta Neuropathol Commun, 11, 2023
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6NWP
| Chronic traumatic encephalopathy Type I Tau filament | 分子名称: | Microtubule-associated protein tau | 著者 | Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W. | 登録日 | 2019-02-07 | 公開日 | 2019-03-27 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature, 568, 2019
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9ERM
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8ORG
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9EOE
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5MP5
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7QKW
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8PII
| VHH Z70 mutant 3 in interaction with PHF6 Tau peptide | 分子名称: | Microtubule-associated protein tau, VHH Z70 Mutant 3 | 著者 | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | 登録日 | 2023-06-21 | 公開日 | 2023-07-05 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein. J.Biol.Chem., 300, 2024
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8TTN
| PHF1-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S396E, S400E, T403E, S404E) | 分子名称: | Microtubule-associated protein tau | 著者 | El Mammeri, N, Dregni, A.J, Duan, P, Hong, M. | 登録日 | 2023-08-14 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation. Proc.Natl.Acad.Sci.USA, 121, 2024
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7QK3
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7EYC
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7P6C
| Limbic-predominant neuronal inclusion body 4R tauopathy type 2 tau filament | 分子名称: | Microtubule-associated protein tau | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | 登録日 | 2021-07-15 | 公開日 | 2021-09-15 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structure-based classification of tauopathies. Nature, 598, 2021
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5DMG
| X-RAY STRUCTURE OF THE FAB FRAGMENT OF THE ANTI TAU ANTIBODY RB86 IN COMPLEX WITH THE PHOSPHORYLATED TAU PEPTIDE (416-430) | 分子名称: | Microtubule-associated protein, RB86 antibody Fab fragment heavy chain, RB86 antibody Fab fragment light chain | 著者 | Benz, J, Lorenz, S, Georges, G, Jochner, A, Goepfert, U, Grueninger, F, Bujotzek, A. | 登録日 | 2015-09-08 | 公開日 | 2015-12-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | VH-VL orientation prediction for antibody humanization candidate selection: A case study. Mabs, 8, 2016
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9BBL
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9ERN
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8ORF
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