6HHQ
| Crystal structure of compound C45 bound to the yeast 80S ribosome | 分子名称: | (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Pellegrino, S, Vanderwal, C.D, Yusupov, M. | 登録日 | 2018-08-28 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.10000038 Å) | 主引用文献 | Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47, 2019
|
|
5ON6
| Crystal structure of haemanthamine bound to the 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Pellegrino, S, Meyer, M, Yusupova, G, Yusupov, M. | 登録日 | 2017-08-03 | 公開日 | 2018-02-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.10000229 Å) | 主引用文献 | The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth. Structure, 26, 2018
|
|
8CKU
| Translocation intermediate 1 (TI-1*) of 80S S. cerevisiae ribosome with ligands and eEF2 in the absence of sordarin | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | 登録日 | 2023-02-16 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
|
|
7BT6
| |
5DAT
| Complex of yeast 80S ribosome with hypusine-containing eIF5A | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-20 | 公開日 | 2016-08-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
|
|
6XIR
| Cryo-EM Structure of K63 Ubiquitinated Yeast Translocating Ribosome under Oxidative Stress | 分子名称: | 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Zhou, Y, Bartesaghi, A, Silva, G.M. | 登録日 | 2020-06-21 | 公開日 | 2020-08-26 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
8K2D
| Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | 登録日 | 2023-07-12 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
|
|
7ZS5
| Structure of 60S ribosomal subunit from S. cerevisiae with eIF6 and tRNA | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | 登録日 | 2022-05-06 | 公開日 | 2023-02-22 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
|
|
4U50
| Crystal structure of Verrucarin bound to the yeast 80S ribosome | 分子名称: | (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
|
|
4U55
| Crystal structure of Cryptopleurine bound to the yeast 80S ribosome | 分子名称: | (14aR)-2,3,6-trimethoxy-11,12,13,14,14a,15-hexahydro-9H-dibenzo[f,h]pyrido[1,2-b]isoquinoline, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
|
|
4U4Y
| Crystal structure of Pactamycin bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
|
|
6T7I
| Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | 登録日 | 2019-10-22 | 公開日 | 2019-12-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
|
|
4U51
| Crystal structure of Narciclasine bound to the yeast 80S ribosome | 分子名称: | (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
|
|
4U3N
| Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-22 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
|
|
6M62
| |
6RZZ
| |
7BTB
| |
7RR5
| Structure of ribosomal complex bound with Rbg1/Tma46 | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... | 著者 | Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H. | 登録日 | 2021-08-09 | 公開日 | 2021-11-10 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells. Cell Rep, 37, 2021
|
|
5LYB
| |
5DC3
| Complex of yeast 80S ribosome with non-modified eIF5A | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-23 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome. J.Mol.Biol., 428, 2016
|
|
6S47
| Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1 | 分子名称: | 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V. | 登録日 | 2019-06-26 | 公開日 | 2019-07-24 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling. Nucleic Acids Res., 47, 2019
|
|
6RI5
| |
7B7D
| Yeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAs | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Ranjan, N, Pochopien, A.A, Wu, C.C, Beckert, B, Blanchet, S, Green, R, Rodnina, M.V, Wilson, D.N. | 登録日 | 2020-12-10 | 公開日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | eEF3 promotes late stages of tRNA translocation including E-tRNA release from the ribosome To Be Published
|
|
5TGA
| |
5T62
| Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3-Tif6-Lsg1 Complex | 分子名称: | 25S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ... | 著者 | Malyutin, A.G, Musalgaonkar, S, Patchett, S, Frank, J, Johnson, A.W. | 登録日 | 2016-09-01 | 公開日 | 2017-02-08 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis. EMBO J., 36, 2017
|
|