5T62

Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3-Tif6-Lsg1 Complex

This is a non-PDB format compatible entry.

Summary for 5T62

• Entry DOI: 10.2210/pdb5t62/pdb
• Related: 5T6R
• EMDB information: 8362 8368
• Descriptor: Eukaryotic translation initiation factor 6, 60S ribosomal protein L7-A, 60S ribosomal protein L8-A, ... (51 entities in total)
• Functional Keywords: ribosome biogenesis, 60s, nmd3, lsg1, tif6, cryo-em, ribosome
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 47
• Total formula weight: 2110893.60

Authors

Malyutin, A.G.,Musalgaonkar, S.,Patchett, S.,Frank, J.,Johnson, A.W. (deposition date: 2016-09-01, release date: 2017-02-08, Last modification date: 2019-12-18)

• Primary citation: Malyutin, A.G.,Musalgaonkar, S.,Patchett, S.,Frank, J.,Johnson, A.W.; Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis.; EMBO J., 36:854-868, 2017; PubMed: 28179369; DOI: 10.15252/embj.201696012

Experimental method

ELECTRON MICROSCOPY (3.3 Å)