5T6R

Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3 Complex

This is a large structure.

Summary for 5T6R

Related5T62
EMDB information8362 8368
Descriptor25S Ribosomal RNA, 5S Ribosomal RNA, 5.8S Ribosomal RNA, ... (48 entities in total)
Functional Keywordsribosome biogenesis, 60s, nmd3, lsg1, tif6, cryo-em, ribosome
Biological sourceSaccharomyces cerevisiae
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Total number of polymer chains45
Total molecular weight2050798.01
Authors
Malyutin, A.G.,Musalgaonkar, S.,Patchett, S.,Frank, J.,Johnson, A.W. (deposition date: 2016-09-01, release date: 2017-02-08, Last modification date: 2018-10-03)
Primary citation
Malyutin, A.G.,Musalgaonkar, S.,Patchett, S.,Frank, J.,Johnson, A.W.
Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis.
EMBO J., 36:854-868, 2017
PubMed: 28179369 (PDB entries with the same primary citation)
DOI: 10.15252/embj.201696012
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (4.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone11.9%5.8%0.44MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 5t6r
no rotation
Molmil generated image of 5t6r
rotated about x axis by 90°
Molmil generated image of 5t6r
rotated about y axis by 90°
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