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PDB: 534 件

7M4O
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BU of 7m4o by Molmil
Crystal structure of phosphorylated RBR E3 ligase RNF216 in complex with K63-linked di-ubiquitin
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, E3 ubiquitin-protein ligase RNF216, GLYCEROL, ...
著者Cotton, T.R, Lechtenberg, B.C.
登録日2021-03-21
公開日2022-01-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216.
Mol.Cell, 82, 2022
6RYA
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BU of 6rya by Molmil
Structure of Dup1 mutant H67A:Ubiquitin complex
分子名称: Polyubiquitin-C, Septation initiation protein
著者Donghyuk, S, Ivan, D.
登録日2019-06-10
公開日2019-11-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB.
Mol.Cell, 77, 2020
4AP4
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BU of 4ap4 by Molmil
Rnf4 - ubch5a - ubiquitin heterotrimeric complex
分子名称: E3 UBIQUITIN LIGASE RNF4, UBIQUITIN C, UBIQUITIN-CONJUGATING ENZYME E2 D1, ...
著者Plechanovova, A, Hay, R.T, Tatham, M.H, Jaffray, E, Naismith, J.H.
登録日2012-03-30
公開日2012-07-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure of a Ring E3 Ligase and Ubiquitin-Loaded E2 Primed for Catalysis
Nature, 489, 2012
5GO8
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BU of 5go8 by Molmil
Linear tetra-ubiquitin
分子名称: D-ubiquitin, ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-26
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
3ZNI
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BU of 3zni by Molmil
Structure of phosphoTyr363-Cbl-b - UbcH5B-Ub - ZAP-70 peptide complex
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL-B, ...
著者Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T.
登録日2013-02-14
公開日2013-07-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Essentiality of a Non-Ring Element in Priming Donor Ubiquitin for Catalysis by a Monomeric E3.
Nat.Struct.Mol.Biol., 20, 2013
5ZQ4
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BU of 5zq4 by Molmil
PDE-Ubi-ADPr
分子名称: ADENOSINE MONOPHOSPHATE, SidE, ubiquitin
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.217 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
6QK9
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BU of 6qk9 by Molmil
A dimeric ubiquitin formed by a single amino acid substitution
分子名称: Polyubiquitin-B
著者Gabrielsen, M, Kowalczyk, D, Buetow, L, Huang, D.T.
登録日2019-01-28
公開日2019-07-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.231 Å)
主引用文献Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation.
Structure, 27, 2019
8CMR
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BU of 8cmr by Molmil
Linear specific OTU-type DUB SnOTU from the pathogen S. negenvensis in complex with linear di-ubiquitin
分子名称: OTU domain-containing protein, Polyubiquitin-B
著者Uthoff, M, Hermanns, T, Boll, V, Hofmann, K, Baumann, U.
登録日2023-02-21
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis.
Nat Commun, 14, 2023
2W9N
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BU of 2w9n by Molmil
crystal structure of linear di-ubiquitin
分子名称: CHLORIDE ION, UBIQUITIN, ZINC ION
著者Komander, D, Reyes-Turcu, F, Wilkinson, K.D, Barford, D.
登録日2009-01-27
公開日2009-04-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Molecular Discrimination of Structurally Equivalent Lys 63-Linked and Linear Polyubiquitin Chains.
Embo Rep., 10, 2009
1CMX
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BU of 1cmx by Molmil
STRUCTURAL BASIS FOR THE SPECIFICITY OF UBIQUITIN C-TERMINAL HYDROLASES
分子名称: PROTEIN (UBIQUITIN YUH1-UBAL)
著者Johnston, S.C, Riddle, S.M, Cohen, R.E, Hill, C.P.
登録日1999-05-12
公開日1999-07-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for the specificity of ubiquitin C-terminal hydrolases.
EMBO J., 18, 1999
5XPK
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BU of 5xpk by Molmil
Crystal structure of ubiquitin-k6mimic
分子名称: D-ubiquitin, Ubiquitin
著者Man, P, Shuai, G, Qian, Q, Lei, L.
登録日2017-06-03
公開日2017-07-19
実験手法X-RAY DIFFRACTION (2.274 Å)
主引用文献Structure of ubiquitin-k6mimic at 2.27 Angstroms resolution.
To Be Published
5VZW
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BU of 5vzw by Molmil
TRIM23 RING domain in complex with UbcH5-Ub
分子名称: E3 ubiquitin-protein ligase TRIM23, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
著者Pornillos, O, Dawidziak, D.
登録日2017-05-29
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.278 Å)
主引用文献Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.
Proteins, 85, 2017
1NBF
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BU of 1nbf by Molmil
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
分子名称: Ubiquitin aldehyde, Ubiquitin carboxyl-terminal hydrolase 7
著者Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y.
登録日2002-12-02
公開日2003-01-07
最終更新日2018-10-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
Cell(Cambridge,Mass.), 111, 2002
4UEL
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BU of 4uel by Molmil
UCH-L5 in complex with ubiquitin-propargyl bound to the RPN13 DEUBAD domain
分子名称: POLYUBIQUITIN-B, PROTEASOMAL UBIQUITIN RECEPTOR ADRM1, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5
著者Sahtoe, D.D, Van Dijk, W.J, El Oualid, F, Ekkebus, R, Ovaa, H, Sixma, T.K.
登録日2014-12-18
公開日2015-03-04
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Mol.Cell, 57, 2015
6XZ1
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BU of 6xz1 by Molmil
Conjugate of the HECT domain of HUWE1 with ubiquitin
分子名称: HECT, UBA and WWE domain containing 1, isoform CRA_a, ...
著者Liu, B, Seenivasan, A, Nair, R, Chen, D, Lowe, E.D, Lorenz, S.
登録日2020-01-31
公開日2021-08-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe.
Acs Chem.Biol., 16, 2021
6PGV
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BU of 6pgv by Molmil
Human Josephin-2 in complex with ubiquitin
分子名称: ETHANAMINE, Josephin-2, Polyubiquitin-B
著者Grasty, K.C, Weeks, S.D, Loll, P.J.
登録日2019-06-24
公開日2019-10-23
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the activity and regulation of human Josephin-2
J.Struct.Biol., 3, 2019
3ZNH
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BU of 3znh by Molmil
Crimean Congo Hemorrhagic Fever Virus OTU domain in complex with ubiquitin-propargyl.
分子名称: POLYUBIQUITIN-B, UBIQUITIN THIOESTERASE
著者Ekkebus, R, vanKasteren, S.I, Kulathu, Y, Scholten, A, Berlin, I, deJong, A, Goerdayal, G, Neefjes, J, Heck, A.J.R, Komander, D, Ovaa, H.
登録日2013-02-14
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献On Terminal Alkynes that Can React with Active-Site Cysteine Nucleophiles in Proteases.
J.Am.Chem.Soc., 135, 2013
2WDT
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BU of 2wdt by Molmil
Crystal structure of Plasmodium falciparum UCHL3 in complex with the suicide inhibitor UbVME
分子名称: CHLORIDE ION, UBIQUITIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L3
著者Weihofen, W.A, Artavanis-Tsakonas, K, Gaudet, R, Ploegh, H.L.
登録日2009-03-26
公開日2009-12-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterization and Structural Studies of the Plasmodium Falciparum Ubiquitin and Nedd8 Hydrolase Uchl3.
J.Biol.Chem., 285, 2010
3WXF
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BU of 3wxf by Molmil
Crystal structure of CYLD USP domain (C596S E674Q) in complex with Met1-linked diubiquitin
分子名称: SULFATE ION, Ubiquitin, Uncharacterized protein
著者Sato, Y, Fukai, S.
登録日2014-07-30
公開日2015-02-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity.
Nat.Struct.Mol.Biol., 22, 2015
3H7S
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BU of 3h7s by Molmil
Crystal structures of K63-linked di- and tri-ubiquitin reveal a highly extended chain architecture
分子名称: Ubiquitin, ZINC ION
著者Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J.
登録日2009-04-28
公開日2009-09-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture.
Proteins, 77, 2009
4ZFT
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BU of 4zft by Molmil
Catalytic domain of Sst2 F403W mutant bound to ubiquitin
分子名称: 1,2-ETHANEDIOL, AMSH-like protease sst2, Polyubiquitin-B, ...
著者Bueno, A.N.
登録日2015-04-21
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Structure of the catalytic domain of Sst2 mutant F403W bound to ubiquitin at 2.3 Angstroms
To Be Published
3C0R
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BU of 3c0r by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
分子名称: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
著者Messick, T.E, Marmorstein, R.
登録日2008-01-21
公開日2008-02-19
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.315 Å)
主引用文献Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
6KBE
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BU of 6kbe by Molmil
Structure of Deubiquitinase
分子名称: Polyubiquitin-C, Ubiquitin thioesterase
著者Lu, L.N, Liu, L, Wang, F.
登録日2019-06-24
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.339 Å)
主引用文献Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
Nat Commun, 13, 2022
6DGF
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BU of 6dgf by Molmil
Ubiquitin Variant bound to USP2
分子名称: Polyubiquitin-B, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 2, ...
著者Manczyk, N, Sicheri, F.
登録日2018-05-17
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases.
J. Mol. Biol., 431, 2019
5OHK
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BU of 5ohk by Molmil
Crystal structure of USP30 in covalent complex with ubiquitin propargylamide (high resolution)
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, ...
著者Gersch, M, Komander, D.
登録日2017-07-17
公開日2017-09-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Mechanism and regulation of the Lys6-selective deubiquitinase USP30.
Nat. Struct. Mol. Biol., 24, 2017

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