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PDB: 541 件

4LCD
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BU of 4lcd by Molmil
Structure of an Rsp5xUbxSna3 complex: Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
分子名称: E3 ubiquitin-protein ligase RSP5, Protein SNA3, Ubiquitin
著者Kamadurai, H.B, Miller, D, Schulman, B.A.
登録日2013-06-21
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3.
Elife, 2, 2013
7W38
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BU of 7w38 by Molmil
Structure of USP14-bound human 26S proteasome in state EA2.0_UBL
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7E8I
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BU of 7e8i by Molmil
Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin
分子名称: BRCA1-associated RING domain protein 1, DNA (145-MER), Histone H2A, ...
著者Dai, Y, Dai, L, Zhou, Z.
登録日2021-03-01
公開日2021-06-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.
Mol.Cell, 81, 2021
7K6Q
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BU of 7k6q by Molmil
Active state Dot1 bound to the H4K16ac nucleosome
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J.
登録日2020-09-21
公開日2021-02-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Science, 371, 2021
5YIK
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BU of 5yik by Molmil
Structure of a Legionella effector with its substrate
分子名称: SdeA, ubiquitin
著者Feng, Y, Dong, Y, Liu, Z.
登録日2017-10-05
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
4DHZ
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BU of 4dhz by Molmil
The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub
分子名称: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ...
著者Wiener, R, Zhang, X, Wang, T, Wolberger, C.
登録日2012-01-30
公開日2012-02-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
7W3U
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BU of 7w3u by Molmil
USP34 catalytic domain in complex with UbPA
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 34, ZINC ION, ...
著者Xu, G.L, Ming, Z.H.
登録日2021-11-26
公開日2022-06-01
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Structural Insights into the Catalytic Mechanism and Ubiquitin Recognition of USP34.
J.Mol.Biol., 434, 2022
5LN1
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BU of 5ln1 by Molmil
STRUCTURE OF UBIQUITYLATED-RPN10 FROM YEAST;
分子名称: 26S proteasome regulatory subunit RPN10, Polyubiquitin-B
著者Keren-Kaplan, T, Attali, I, Levin-Kravets, O, Prag, G.
登録日2016-08-02
公開日2016-10-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism.
Nat Commun, 7, 2016
5O44
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BU of 5o44 by Molmil
Crystal structure of unbranched mixed tri-Ubiquitin chain containing K48 and K63 linkages.
分子名称: MAGNESIUM ION, Polyubiquitin-B, SULFATE ION, ...
著者Padala, P, Isupov, M.N, Wiener, R.
登録日2017-05-26
公開日2017-11-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献The Crystal Structure and Conformations of an Unbranched Mixed Tri-Ubiquitin Chain Containing K48 and K63 Linkages.
J. Mol. Biol., 429, 2017
4WUR
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BU of 4wur by Molmil
The crystal structure of the MERS-CoV papain-like protease (C111S) with human ubiquitin
分子名称: ISOPROPYL ALCOHOL, Papain-like protease, Polyubiquitin-B, ...
著者Lei, J, Hilgenfeld, R.
登録日2014-11-03
公開日2014-11-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin.
Virol Sin, 31, 2016
8PP6
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BU of 8pp6 by Molmil
human RYBP-PRC1 bound to H2AK118ub1 nucleosome
分子名称: DNA (215-MER), Histone H2A, Histone H2B, ...
著者Ciapponi, M, Benda, C, Mueller, J.
登録日2023-07-06
公開日2024-04-03
最終更新日2024-07-31
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1.
Nat.Struct.Mol.Biol., 31, 2024
5YIJ
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BU of 5yij by Molmil
Structure of a Legionella effector with substrates
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SdeA, Ubiquitin
著者Feng, Y, Mu, Y, Wang, H.
登録日2017-10-05
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
6W9D
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BU of 6w9d by Molmil
RNF12 RING domain in complex with a Ube2d2~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RLIM, IODIDE ION, Ubiquitin, ...
著者Middleton, A.J, Day, C.L.
登録日2020-03-22
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
7DNI
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BU of 7dni by Molmil
MDA5 CARDs-MAVS CARD polyUb complex
分子名称: Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin
著者Song, B, Chen, Y, Luo, D.H, Zheng, J.
登録日2020-12-09
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
7AY2
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BU of 7ay2 by Molmil
Crystal structure of truncated USP1-UAF1 reacted with ubiquitin-prg
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 1, WD repeat-containing protein 48, ...
著者Arkinson, C, Rennie, M.L, Walden, H.
登録日2020-11-10
公開日2021-03-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of FANCD2 deubiquitination by USP1-UAF1.
Nat.Struct.Mol.Biol., 28, 2021
7W3H
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BU of 7w3h by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
6MSD
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BU of 6msd by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
7W39
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BU of 7w39 by Molmil
Structure of USP14-bound human 26S proteasome in state EA2.1_UBL
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3G
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BU of 7w3g by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
5ZBU
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BU of 5zbu by Molmil
Crystal Structure of PA-TM-RING E3 ligase RNF13 RING domain in complex with E2~Ub
分子名称: E3 ubiquitin-protein ligase RNF13, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
著者Datta, A.B, Sarkar, S.
登録日2018-02-12
公開日2019-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structure of PA-TM-RING E3 ligase RNF13 RING domain in complex with E2~Ub
To Be Published
8SVF
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BU of 8svf by Molmil
BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
分子名称: DNA/RNA (187-MER), DNA/RNA (327-MER), Histone H2A type 1, ...
著者Thomas, J.F, Valencia-Sanchez, M.I, Armache, K.-J.
登録日2023-05-16
公開日2023-08-30
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.
Sci Adv, 9, 2023
7EB9
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BU of 7eb9 by Molmil
The structure of the A20-binding inhibitor of NF-kB 1 in complex with tetra-ubiquitin
分子名称: TNFAIP3-interacting protein 1, tetra ubiquitin
著者Lo, Y.C, Lin, S.C.
登録日2021-03-09
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and Biochemical Basis for Higher-Order Assembly between A20-Binding Inhibitor of NF-kappa B 1 (ABIN1) and M1-Linked Ubiquitins.
J.Mol.Biol., 433, 2021
7K6P
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BU of 7k6p by Molmil
Active state Dot1 bound to the unacetylated H4 nucleosome
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J.
登録日2020-09-21
公開日2021-02-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Science, 371, 2021
8U5H
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BU of 8u5h by Molmil
Cryo-EM structure of human DNMT3A UDR bound to H2AK119ub1-modified nucleosome
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H2A, Histone H2B 1.1, ...
著者Chen, X, Song, J.
登録日2023-09-12
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Cryo-EM structure of human DNMT3A N-terminal domain bound to H2AK119Ub nucleosome
To Be Published
5UDH
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BU of 5udh by Molmil
HHARI/ARIH1-UBCH7~Ubiquitin
分子名称: E3 ubiquitin-protein ligase ARIH1, Ubiquitin C variant, Ubiquitin-conjugating enzyme E2 L3, ...
著者Miller, D.J, Schulman, B.A.
登録日2016-12-27
公開日2017-06-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structural Studies of HHARI/UbcH7Ub Reveal Unique E2Ub Conformational Restriction by RBR RING1.
Structure, 25, 2017

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件を2024-08-14に公開中

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