3N94
| Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain | 分子名称: | Fusion protein of Maltose-binding periplasmic protein and pituitary adenylate cyclase 1 Receptor-short, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Kumar, S, Pioszak, A.A, Swaminathan, K, Xu, H.E. | 登録日 | 2010-05-28 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors. Plos One, 6, 2011
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5CFV
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1OMP
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6QGD
| Structure of human Mcl-1 in complex with thienopyrimidine inhibitor | 分子名称: | 2-[(6-ethyl-5-phenyl-thieno[2,3-d]pyrimidin-4-yl)amino]-3-oxidanyl-propanoic acid, Maltose-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, SODIUM ION, ... | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | 登録日 | 2019-01-11 | 公開日 | 2019-06-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1. Acs Omega, 4, 2019
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1DMB
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6K7F
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3W15
| Structure of peroxisomal targeting signal 2 (PTS2) of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase in complex with Pex7p and Pex21p | 分子名称: | 3-ketoacyl-CoA thiolase, peroxisomal, Maltose-binding periplasmic protein, ... | 著者 | Pan, D, Nakatsu, T, Kato, H. | 登録日 | 2012-11-06 | 公開日 | 2013-07-03 | 最終更新日 | 2017-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of peroxisomal targeting signal-2 bound to its receptor complex Pex7p-Pex21p Nat.Struct.Mol.Biol., 20, 2013
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5ZCA
| Crystal structure of lambda repressor (1-20) fused with maltose-binding protein | 分子名称: | CITRIC ACID, Repressor protein cI,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Hanazono, Y, Takeda, K, Miki, K. | 登録日 | 2018-02-16 | 公開日 | 2018-08-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Co-translational folding of alpha-helical proteins: structural studies of intermediate-length variants of the lambda repressor Febs Open Bio, 8, 2018
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5AZ9
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6V2E
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5H7N
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7P0F
| Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0028125 | 分子名称: | (1S,10R,23E)-12-methyl-10-[(7-methyl-1H-indazol-5-yl)methyl]-15,18,21-trioxa-5,9,12,27,29-pentazapentacyclo[23.5.2.11,4.13,7.028,31]tetratriaconta-3(33),4,6,23,25(32),26,28(31)-heptaene-8,11,30-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ... | 著者 | Southall, S.M, Watson, S.P. | 登録日 | 2021-06-29 | 公開日 | 2022-06-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein-Ligand Complexes. Acs Chem Neurosci, 13, 2022
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3SEY
| Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II) | 分子名称: | ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | 著者 | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-11 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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1LAX
| CRYSTAL STRUCTURE OF MALE31, A DEFECTIVE FOLDING MUTANT OF MALTOSE-BINDING PROTEIN | 分子名称: | MALTOSE-BINDING PROTEIN MUTANT MALE31, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Saul, F.A, Mourez, M, Vulliez-le Normand, B, Sassoon, N, Bentley, G.A, Betton, J.M. | 登録日 | 2002-03-29 | 公開日 | 2003-03-04 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of a defective folding protein PROTEIN SCI., 12, 2003
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3SEU
| Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form III) | 分子名称: | ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | 著者 | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-11 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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7FBC
| De novo design protein D22 with MBP tag | 分子名称: | Maltodextrin-binding protein,De novo design protein D22 | 著者 | Bin, H. | 登録日 | 2021-07-09 | 公開日 | 2021-12-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A backbone-centred energy function of neural networks for protein design. Nature, 602, 2022
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3RUM
| New strategy to analyze structures of glycopeptide antibiotic-target complexes | 分子名称: | 3-amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranose, ISOPROPYL ALCOHOL, Maltose-binding periplasmic protein, ... | 著者 | Economou, N.J, Weeks, S.D, Grasty, K.C, Nahoum, V, Loll, P.J. | 登録日 | 2011-05-05 | 公開日 | 2012-06-06 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | A carrier protein strategy yields the structure of dalbavancin. J.Am.Chem.Soc., 134, 2012
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3G7V
| Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein | 分子名称: | GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ... | 著者 | Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D. | 登録日 | 2009-02-10 | 公開日 | 2009-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009
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5AQ9
| DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography | 分子名称: | MALTOSE-BINDING PERIPLASMIC PROTEIN, OFF7_DB08V4 | 著者 | Batyuk, A, Wu, Y, Honegger, A, Heberling, M, Plueckthun, A. | 登録日 | 2015-09-21 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography J.Mol.Biol., 428, 2016
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7WR3
| Crystal structure of MBP-fused OspC3 in complex with calmodulin | 分子名称: | Calmodulin-1, MBP-fused OspC3, NICOTINAMIDE, ... | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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3WAI
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9BCG
| Myeloid cell leukemia-1 (Mcl-1) complexed with compound | 分子名称: | 7-[(4R,5S,6P)-7-chloro-10-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-4-methyl-1-oxo-6-(1,3,5-trimethyl-1H-pyrazol-4-yl)-3,4-dihydropyrazino[1,2-a]indol-2(1H)-yl]-4,5-dimethoxy-1-methyl-1H-indole-2-carboxylic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Zhao, B, Fesik, S.W. | 登録日 | 2024-04-09 | 公開日 | 2024-08-07 | 最終更新日 | 2024-09-11 | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | 主引用文献 | Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors. J.Med.Chem., 67, 2024
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4TSM
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5M15
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8CDY
| N-terminal domain of human apolipoprotein E | 分子名称: | Maltodextrin-binding protein,Apolipoprotein E | 著者 | Marek, M, Nemergut, M. | 登録日 | 2023-02-01 | 公開日 | 2023-07-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate. Mol Neurodegener, 18, 2023
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