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PDB: 472 件
6DM8
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Understanding the Species Selectivity of Myeloid cell leukemia-1 (Mcl-1) inhibitors
分子名称: 4-{8-chloro-11-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-1-oxo-7-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4,5-dihydro-1H-[1,4]diazepino[1,2-a]indol-2(3H)-yl}-1-methyl-1H-indole-6-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog - MBP chimera, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Zhao, B.
登録日2018-06-04
公開日2018-08-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Understanding the Species Selectivity of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors.
Biochemistry, 57, 2018
4O2X
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BU of 4o2x by Molmil
Structure of a malarial protein
分子名称: Maltose-binding periplasmic protein, ATP-dependent Clp protease adaptor protein ClpS containing protein chimeric construct
著者AhYoung, A.P, Koehl, A, Cascio, D, Egea, P.F.
登録日2013-12-17
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of a putative ClpS N-end rule adaptor protein from the malaria pathogen Plasmodium falciparum.
Protein Sci., 25, 2016
8AG0
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BU of 8ag0 by Molmil
Crystal structure of mutant PRELID3a-TRIAP1 complex - R53E
分子名称: Maltose/maltodextrin-binding periplasmic protein,TP53-regulated inhibitor of apoptosis 1, PRELI domain containing protein 3A, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose
著者Milara, X, Perez-Dorado, J.I, Matthews, S.J.
登録日2022-07-18
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An intermolecular hydrogen bonded network in the PRELID-TRIAP protein family plays a role in lipid sensing.
Biochim Biophys Acta Proteins Proteom, 1871, 2022
5HZV
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BU of 5hzv by Molmil
Crystal structure of the zona pellucida module of human endoglin/CD105
分子名称: GLYCEROL, Maltose-binding periplasmic protein,Endoglin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Bokhove, M, Saito, T, Jovine, L.
登録日2016-02-03
公開日2017-06-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Cell Rep, 19, 2017
3OB4
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BU of 3ob4 by Molmil
MBP-fusion protein of the major peanut allergen Ara h 2
分子名称: CHLORIDE ION, Maltose ABC transporter periplasmic protein,Arah 2, SULFATE ION, ...
著者Mueller, G.A, Gosavi, R.A, Moon, A.F, London, R.E, Pedersen, L.C.
登録日2010-08-06
公開日2011-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.706 Å)
主引用文献Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity.
Allergy, 66, 2011
3N95
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BU of 3n95 by Molmil
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2
分子名称: Maltose binding protein-CRFR2 alpha extracellular domain, Urocortin-2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
登録日2010-05-28
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
5ZNY
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BU of 5zny by Molmil
Structure of mDR3_DD-C363G with MBP tag
分子名称: Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25, SULFATE ION
著者Yin, X, Jin, T.
登録日2018-04-11
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Crystal structure and activation mechanism of DR3 death domain.
Febs J., 286, 2019
8AX5
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BU of 8ax5 by Molmil
Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029881
分子名称: (1~{R},10~{R},20~{E})-12-methyl-10-[(7-methyl-2~{H}-indazol-5-yl)methyl]-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3,5,7(30),20,22,24,28-heptaene-8,11,27-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ...
著者Southall, S.M, Watson, S.P.
登録日2022-08-30
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode.
Acs Med.Chem.Lett., 13, 2022
3N96
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BU of 3n96 by Molmil
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1
分子名称: Maltose binding protein-CRFR2 alpha, Urocortin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
登録日2010-05-28
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3EHS
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BU of 3ehs by Molmil
Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1)
分子名称: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, fusion protein of CRFR1 extracellular domain and MBP
著者Pioszak, A.A, Xu, H.E.
登録日2008-09-14
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1.
J.Biol.Chem., 283, 2008
6DKS
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BU of 6dks by Molmil
Structure of the Rbpj-SHARP-DNA Repressor Complex
分子名称: DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ...
著者Kovall, R.A, VanderWielen, B.D, Yuan, Z.
登録日2018-05-30
公開日2019-01-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site.
Cell Rep, 26, 2019
5EDU
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BU of 5edu by Molmil
Crystal structure of human histone deacetylase 6 catalytic domain 2 in complex with trichostatin A
分子名称: Maltose-binding periplasmic protein, Histone deacetylase 6 chimera, POTASSIUM ION, ...
著者Hai, Y, Christianson, D.W.
登録日2015-10-22
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
7VN6
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BU of 7vn6 by Molmil
Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning CGCACGTGCG
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*CP*GP*CP*AP*CP*GP*TP*GP*CP*GP*AP*AP*A)-3'), Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1, ...
著者Nosaki, S, Tanokura, M, Miyakawa, T.
登録日2021-10-10
公開日2022-12-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Brassinosteroid-induced gene repression requires specific and tight promoter binding of BIL1/BZR1 via DNA shape readout.
Nat.Plants, 8, 2022
8XB3
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BU of 8xb3 by Molmil
Structural mechanism of substrate binding and inhibition of the human Norepinephrine Transporter
分子名称: 1-[(3-iodanylphenyl)methyl]guanidine, 2-acetamido-2-deoxy-beta-D-glucopyranose, GFP-MBP-solute carrier family 6 member 2
著者Ji, W.M, Wu, J.X.
登録日2023-12-05
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural mechanism of substrate binding and inhibition of the human Norepinephrine Transporter
To Be Published
5WVN
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BU of 5wvn by Molmil
Crystal structure of MBS-BaeS fusion protein
分子名称: Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION
著者Wang, W, Zhang, Y, Ran, T, Xu, D.
登録日2016-12-26
公開日2018-01-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14
Proteins, 85, 2017
5E7U
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BU of 5e7u by Molmil
MBP-MamC loop structure, a magnetite biomineralizing protein from Magnetospirillium magneticum AMB-1
分子名称: Maltose-binding periplasmic protein,Tightly bound bacterial magnetic particle protein,Maltose-binding periplasmic protein, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Nudelman, H, Zarivach, R.
登録日2015-10-13
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献MBP-MamC loop structure, a magnetite biomineralizing protein from Magnetospirillium magneticum AMB-1
To Be Published
2R6G
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BU of 2r6g by Molmil
The Crystal Structure of the E. coli Maltose Transporter
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Maltose transport system permease protein malF, Maltose transport system permease protein malG, ...
著者Oldham, M.L, Khare, D, Quiocho, F.A, Davidson, A.L, Chen, J.
登録日2007-09-05
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a catalytic intermediate of the maltose transporter.
Nature, 450, 2007
7XQC
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BU of 7xqc by Molmil
Crystal structure of N-terminal domain of Rv2908c fused with Maltose Binding Protein (MBP)
分子名称: DI(HYDROXYETHYL)ETHER, Fusion protein of Maltose-binding periplasmic protein and RNA-binding protein KhpA
著者Thakur, K.G, Singh, A, Kapoor, S, Deep, A.
登録日2022-05-07
公開日2023-05-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of N-terminal domain of Rv2908c fused with Maltose Binding Protein (MBP)
To Be Published
7B01
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BU of 7b01 by Molmil
ADAMTS13-CUB12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Maltodextrin-binding protein,Maltodextrin-binding protein,Maltodextrin-binding protein,ADAMTS13 CUB12,A disintegrin and metalloproteinase with thrombospondin motifs 13,A disintegrin and metalloproteinase with thrombospondin motifs 13,A disintegrin and metalloproteinase with thrombospondin motifs 13, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Kim, H.J, Emsley, J.
登録日2020-11-18
公開日2021-04-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of ADAMTS13 CUB domains reveals their role in global latency.
Sci Adv, 7, 2021
5V6Y
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Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity and altered selectivity adrenomedullin variant
分子名称: ADM, Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pioszak, A, Booe, J.
登録日2017-03-17
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Probing the Mechanism of Receptor Activity-Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists.
Mol. Pharmacol., 93, 2018
6SLM
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BU of 6slm by Molmil
Crystal structure of full-length HPV31 E6 oncoprotein in complex with LXXLL peptide of ubiquitin ligase E6AP
分子名称: GLYCEROL, Maltose/maltodextrin-binding periplasmic protein,Protein E6,Ubiquitin-protein ligase E3A, ZINC ION, ...
著者Conrady, M, Gogl, G, Cousido-Siah, A, Mitschler, A, Trave, G, Simon, C.
登録日2019-08-20
公開日2020-09-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of High-Risk Papillomavirus 31 E6 Oncogenic Protein and Characterization of E6/E6AP/p53 Complex Formation.
J.Virol., 95, 2020
3MQ9
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BU of 3mq9 by Molmil
Crystal Structure of Ectodomain Mutant of BST-2/Tetherin/CD317 Fused to MBP
分子名称: Bone marrow stromal antigen 2 fused to Maltose-binding periplasmic protein
著者Xiong, Y, Yang, H, Wang, J, Meng, W.
登録日2010-04-27
公開日2010-10-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insight into the mechanisms of enveloped virus tethering by tetherin.
Proc.Natl.Acad.Sci.USA, 107, 2010
6CXS
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BU of 6cxs by Molmil
Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine
分子名称: 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine, Beta-glucuronidase, Maltose/maltodextrin-binding periplasmic protein
著者Wallace, B.D, Redinbo, M.R.
登録日2018-04-04
公開日2019-04-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Targeted inhibition of gut bacterial beta-glucuronidase activity enhances anticancer drug efficacy.
Proc.Natl.Acad.Sci.USA, 2020
4NUF
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BU of 4nuf by Molmil
Crystal Structure of SHP/EID1
分子名称: EID1 peptide, Maltose ABC transporter periplasmic protein, Nuclear receptor subfamily 0 group B member 2 chimeric construct, ...
著者Zhi, X, Zhou, X.E, He, Y, Zechner, C, Suino-Powell, K.M, Kliewer, S.A, Melcher, K, Mangelsdorf, D.J, Xu, H.E.
登録日2013-12-03
公開日2014-01-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into gene repression by the orphan nuclear receptor SHP.
Proc.Natl.Acad.Sci.USA, 111, 2014
4BLB
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BU of 4blb by Molmil
Crystal structure of a human Suppressor of fused (SUFU)-GLI1p complex
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, ZINC FINGER PROTEIN GLI1, ...
著者Cherry, A.L, Finta, C, Karlstrom, M, De Sanctis, D, Toftgard, R, Jovine, L.
登録日2013-05-02
公開日2013-11-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
Acta Crystallogr.,Sect.D, 69, 2013

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