7Y5Q
| Structure of 1:1 PAPP-A.STC2 complex(half map) | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | 登録日 | 2022-06-17 | 公開日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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7Z7H
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8G8W
| Molecular mechanism of nucleotide inhibition of human uncoupling protein 1 | 分子名称: | CARDIOLIPIN, GUANOSINE-5'-TRIPHOSPHATE, Mitochondrial brown fat uncoupling protein 1, ... | 著者 | Gogoi, P, Jones, S.A, Ruprecht, J.J, King, M.S, Lee, Y, Zogg, T, Pardon, E, Chand, D, Steimle, S, Copeman, D, Cotrim, C.A, Steyaert, J, Crichton, P.G, Moiseenkova-Bell, V, Kunji, E.R.S. | 登録日 | 2023-02-20 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of purine nucleotide inhibition of human uncoupling protein 1. Sci Adv, 9, 2023
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8SOJ
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6HDA
| Crystal structure of the potassium channel MtTMEM175 with cesium | 分子名称: | CESIUM ION, DODECYL-BETA-D-MALTOSIDE, Nanobody,Maltose/maltodextrin-binding periplasmic protein, ... | 著者 | Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S. | 登録日 | 2018-08-17 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis for ion selectivity in TMEM175 K+channels. Elife, 9, 2020
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7P1H
| Structure of the V. vulnificus ExoY-G-actin-profilin complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | 著者 | Belyy, A, Merino, F, Raunser, S. | 登録日 | 2021-07-01 | 公開日 | 2021-11-17 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens. Nat Commun, 12, 2021
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6DBU
| Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | 分子名称: | CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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8FNE
| phiPA3 PhuN Tetramer, p2 | 分子名称: | Maltose/maltodextrin-binding periplasmic protein, PhuN | 著者 | Nieweglowska, E.S, Brilot, A.F, Mendez-Moran, M, Kokontis, C, Baek, M, Li, J, Cheng, Y, Baker, D, Bondy-Denomy, J, Agard, D.A. | 登録日 | 2022-12-27 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The phi PA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice. Nat Commun, 14, 2023
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7JHH
| Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Fab and nanobody | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | 著者 | Yan, Y, Murkherjee, S, Zhou, X.E, Xu, T.H, Xu, H.E, Kossiakoff, A.A, Melcher, K. | 登録日 | 2020-07-20 | 公開日 | 2021-07-21 | 最終更新日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373, 2021
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6BUZ
| Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B, ... | 著者 | Chittori, S, Hong, J, Kelly, A.E, Bai, Y, Subramaniam, S. | 登録日 | 2017-12-11 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N. Science, 359, 2018
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7M74
| ATP-bound AMP-activated protein kinase | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | 著者 | Yan, Y, Mukherjee, S, Harikumar, K.G, Strutzenberg, T, Zhou, X.E, Powell, S.K, Xu, T, Sheldon, R, Lamp, J, Brunzelle, J.S, Radziwon, K, Ellis, A, Novick, S.J, Vega, I.E, Jones, R, Miller, L.J, Xu, H.E, Griffin, P.R, Kossiakoff, A.A, Melcher, K. | 登録日 | 2021-03-26 | 公開日 | 2021-12-15 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373, 2021
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7NZM
| Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Yan, Y, Hardwick, S, Ron, D. | 登録日 | 2021-03-24 | 公開日 | 2021-09-29 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
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6DBR
| Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS | 分子名称: | CALCIUM ION, Forward strand of melted RSS substrate DNA, Forward strand of unmelted RSS substrate DNA, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6P6W
| Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state | 分子名称: | Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb | 著者 | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A. | 登録日 | 2019-06-04 | 公開日 | 2019-08-14 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178, 2019
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7VGQ
| Cryo-EM structure of Machupo virus polymerase L in complex with matrix protein Z | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION | 著者 | Zhang, X, Ma, J, Zhang, S. | 登録日 | 2021-09-18 | 公開日 | 2021-09-29 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
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8SOK
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8HGH
| Structure of 2:2 PAPP-A.STC2 complex | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | 登録日 | 2022-11-14 | 公開日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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6DBX
| Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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8SQA
| The cryo-EM structure of the EcBAM/EspP(beta8-12) complex | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Autotransporter protein EspP translocator, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | 著者 | Wu, R, Noinaj, N. | 登録日 | 2023-05-04 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | BAM orchestrates OMP biogenesis using a beta-templating mechanism To Be Published
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8CR9
| Cryo-EM structure of PcrV/Fab(30-B8) | 分子名称: | Heavy chain, Maltose/maltodextrin-binding periplasmic protein,Type III secretion protein PcrV, light chain | 著者 | Yuan, B, Simonis, A, Marlovits, T.C. | 登録日 | 2023-03-08 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa. Cell, 186, 2023
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6N4R
| CryoEM structure of Nav1.7 VSD2 (deactived state) in complex with the gating modifier toxin ProTx2 | 分子名称: | Beta/omega-theraphotoxin-Tp2a, Fab heavy chain, Fab light chain, ... | 著者 | Xu, H, Rohou, A, Arthur, C.P, Estevez, A, Ciferri, C, Payandeh, J, Koth, C.M. | 登録日 | 2018-11-20 | 公開日 | 2019-01-23 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin. Cell, 176, 2019
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7TT4
| BamABCDE bound to substrate EspP class 6 | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | 著者 | Doyle, M.T, Jimah, J.R, Dowdy, T, Ohlemacher, S.I, Larion, M, Hinshaw, J.E, Bernstein, H.D. | 登録日 | 2022-01-31 | 公開日 | 2022-03-30 | 最終更新日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell, 185, 2022
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7TT2
| BamABCDE bound to substrate EspP class 3 | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | 著者 | Doyle, M.T, Jimah, J.R, Dowdy, T, Ohlemacher, S.I, Larion, M, Hinshaw, J.E, Bernstein, H.D. | 登録日 | 2022-01-31 | 公開日 | 2022-03-30 | 最終更新日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell, 185, 2022
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7BXT
| The cryo-EM structure of CENP-A nucleosome in complex with CENP-C peptide and CENP-N N-terminal domain | 分子名称: | CENP-C, DNA (145-mer), Histone H2A type 1-B/E, ... | 著者 | Ariyoshi, M, Makino, F, Fukagawa, T. | 登録日 | 2020-04-20 | 公開日 | 2021-02-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structure of the CENP-A nucleosome in complex with phosphorylated CENP-C. Embo J., 40, 2021
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7VH1
| Cryo-EM structure of Machupo virus dimeric L-Z complex | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION | 著者 | Zhang, X, Ma, J, Zhang, S. | 登録日 | 2021-09-20 | 公開日 | 2021-09-29 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
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