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PDB: 70 件
4YOE
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Structure of UP1 bound to RNA 5'-AGU-3'
分子名称: ACETATE ION, Heterogeneous nuclear ribonucleoprotein A1, RNA AGU, ...
著者Meagher, J.L, Stuckey, J.A.
登録日2015-03-11
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein.
J.Mol.Biol., 427, 2015
5MPL
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BU of 5mpl by Molmil
hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA
分子名称: Heterogeneous nuclear ribonucleoprotein A1, RNA UCAGUU
著者Barraud, P, Allain, F.H.-T.
登録日2016-12-16
公開日2017-07-05
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017
8RZV
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Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
分子名称: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
著者Dunnett, L, Prischi, F.
登録日2024-02-13
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
To Be Published
6J60
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hnRNP A1 reversible amyloid core GFGGNDNFG (residues 209-217)
分子名称: 9-mer peptide (GFGGNDNFG) from Heterogeneous nuclear ribonucleoprotein A1
著者Luo, F, Zhou, H, Gui, X, Li, D, Li, X, Liu, C.
登録日2019-01-12
公開日2019-04-03
最終更新日2024-03-27
実験手法ELECTRON CRYSTALLOGRAPHY (0.96 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
1L3K
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BU of 1l3k by Molmil
UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
分子名称: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1
著者Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M.
登録日2002-02-27
公開日2002-04-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.
Nucleic Acids Res., 30, 2002
2UP1
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BU of 2up1 by Molmil
STRUCTURE OF UP1-TELOMERIC DNA COMPLEX
分子名称: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), PROTEIN (HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1)
著者Ding, J, Hayashi, M.K, Krainer, A.R, Xu, R.-M.
登録日1998-07-10
公開日1999-11-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA.
Genes Dev., 13, 1999
1HA1
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HNRNP A1 (RBD1,2) FROM HOMO SAPIENS
分子名称: HNRNP A1
著者Shamoo, Y, Krueger, U, Rice, L, Williams, K.R, Steitz, T.A.
登録日1996-10-30
公開日1997-05-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of the two RNA binding domains of human hnRNP A1 at 1.75 A resolution.
Nat.Struct.Biol., 4, 1997
7ZJ2
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BU of 7zj2 by Molmil
Amyloid fibril (in vitro) from full-length hnRNPA1 protein
分子名称: Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1
著者Sharma, K, Banerjee, S, Schmidt, M, Faendrich, M.
登録日2022-04-08
公開日2023-08-02
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril.
J.Mol.Biol., 435, 2023
9F1S
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Structure of UP1 S4ES6E phosphomimetic mutant
分子名称: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
著者Dunnett, L, Prischi, F.
登録日2024-04-20
公開日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of UP1 S4ES6E phosphomimetic mutant
To Be Published
7BX7
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BU of 7bx7 by Molmil
Cryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain
分子名称: Heterogeneous nuclear ribonucleoprotein A1
著者Sun, Y.P, Zhao, K, Liu, C, Li, D.
登録日2020-04-17
公開日2020-11-18
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure.
Nat Commun, 11, 2020
1UP1
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BU of 1up1 by Molmil
UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
分子名称: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1
著者Xu, R.-M, Jokhan, L, Cheng, X, Mayeda, A, Krainer, A.R.
登録日1997-03-12
公開日1997-09-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs.
Structure, 5, 1997
5MPG
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BU of 5mpg by Molmil
Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA
分子名称: Heterogeneous nuclear ribonucleoprotein A1, RNA UUAGGUC
著者Barraud, P, Allain, F.H.-T.
登録日2016-12-16
公開日2017-07-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017
2LYV
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BU of 2lyv by Molmil
Solution structure of the two RRM domains of hnRNP A1 (UP1) using segmental isotope labeling
分子名称: Heterogeneous nuclear ribonucleoprotein A1
著者Barraud, P, Allain, F.H.-T.
登録日2012-09-19
公開日2012-12-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the two RNA recognition motifs of hnRNP A1 using segmental isotope labeling: how the relative orientation between RRMs influences the nucleic acid binding topology.
J.Biomol.Nmr, 55, 2013
2H4M
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BU of 2h4m by Molmil
Karyopherin Beta2/Transportin-M9NLS
分子名称: Heterogeneous nuclear ribonucleoprotein A1, Transportin-1
著者Chook, Y.M, Cansizoglu, A.E.
登録日2006-05-24
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Rules for nuclear localization sequence recognition by karyopherin beta 2.
Cell(Cambridge,Mass.), 126, 2006
1U1K
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BU of 1u1k by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTT 7DA GGG); A Human Telomeric Repeat Containing 7-deaza-adenine
分子名称: 5'-D(*TP*AP*GP*GP*GP*TP*TP*(7DA)P*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
著者Myers, J.C, Shamoo, Y.
登録日2004-07-15
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1N
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BU of 1u1n by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTA (PRN)GG); A Human Telomeric Repeat Containing Nebularine
分子名称: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(PRN)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
著者Myers, J.C, Shamoo, Y.
登録日2004-07-15
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
5ZGD
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BU of 5zgd by Molmil
hnRNPA1 reversible amyloid core GFGGNDNFG (residues 209-217) determined by X-ray
分子名称: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHE-GLY
著者Gui, X, Xie, M, Zhao, M, Luo, F, He, J, Li, D, Liu, C.
登録日2018-03-08
公開日2019-04-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
5ZGL
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BU of 5zgl by Molmil
hnRNP A1 segment GGGYGGS (residues 234-240)
分子名称: 7-mer peptide from Heterogeneous nuclear ribonucleoprotein A1
著者Xie, M, Luo, F, Gui, X, Zhao, M, He, J, Li, D, Liu, C.
登録日2018-03-09
公開日2019-04-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
6BXX
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GYNGFG from low-complexity domain of hnRNPA1, residues 243-248
分子名称: hnRNPA1
著者Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S.
登録日2017-12-19
公開日2018-04-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
6DCL
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BU of 6dcl by Molmil
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
分子名称: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
著者Kooshapur, H, Sattler, M.
登録日2018-05-07
公開日2018-06-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.497 Å)
主引用文献Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
8IK7
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BU of 8ik7 by Molmil
Cryo-EM structure of hnRAC1 fibril.
分子名称: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHE-GLY
著者Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
登録日2023-02-28
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Formed fibrils of hnRNP A1 reversible amyloid core GFGGNDNFG (residues 209-217)
To Be Published
8IKS
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BU of 8iks by Molmil
Cryo-EM structure of hnRAC1-2I8I fibril.
分子名称: GLY-PHI-GLY-GLY-ASN-ASP-ASN-PHI-GLY
著者Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
登録日2023-03-01
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Cryo-EM structure of hnRAC1-2I8I fibril.
To Be Published
8IKP
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Cryo-EM structure of hnRAC1-8I fibril
分子名称: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHI-GLY
著者Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
登録日2023-02-28
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Cryo-EM structure of hnRAC1-8I fibril
To Be Published
8IKB
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Cryo-EM structure of hnRAC1-2I fibril.
分子名称: GLY-PHI-GLY-GLY-ASN-ASP-ASN-PHE-GLY
著者Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
登録日2023-02-28
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Cryo-EM structure of hnRAC1-2I fibril.
To Be Published
1PO6
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Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
分子名称: 5'-D(*T*AP*GP*GP*(6MI)P*TP*TP*AP*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
著者Myers, J.C, Moore, S.A, Shamoo, Y.
登録日2003-06-13
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.BIOL.CHEM., 278, 2003

 

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