1N26
 
 | | Crystal Structure of the extra-cellular domains of Human Interleukin-6 Receptor alpha chain | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Varghese, J.N, Moritz, R.L, Lou, M.-Z, van Donkelaar, A, Ji, H, Ivancic, N, Branson, K.M, Hall, N.E, Simpson, R.J. | | 登録日 | 2002-10-22 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the extracellular domains of the human interleukin-6 receptor alpha-chain.
Proc.Natl.Acad.Sci.USA, 99, 2002
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5FUC
 | | Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80 together in a stable complex: implications for new therapeutic strategies | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-6, INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, ... | | 著者 | Adams, R, Griffin, R, Doyle, C, Ettorre, A. | | 登録日 | 2016-01-25 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling.
Sci Rep, 7, 2017
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7DC8
 | | Crystal structure of Switch Ab Fab and hIL6R in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Interleukin-6 receptor subunit alpha, SULFATE ION, ... | | 著者 | Kadono, S, Fukami, T.A, Kawauchi, H, Torizawa, T, Mimoto, F. | | 登録日 | 2020-10-23 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.757 Å) | | 主引用文献 | Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment.
Cell Rep, 33, 2020
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8QY5
 | | Structure of interleukin 6. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ... | | 著者 | Gardner, S, Bubeck, D, Jin, Y. | | 登録日 | 2023-10-25 | | 公開日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of interleukin 6.
To Be Published
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8QY6
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8IOW
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8D82
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8J6F
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1P9M
 | | Crystal structure of the hexameric human IL-6/IL-6 alpha receptor/gp130 complex | | 分子名称: | Interleukin-6, Interleukin-6 receptor alpha chain, Interleukin-6 receptor beta chain | | 著者 | Boulanger, M.J, Chow, D.C, Brevnova, E.E, Garcia, K.C. | | 登録日 | 2003-05-12 | | 公開日 | 2003-07-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Hexameric Structure and Assembly of the Interleukin-6/IL-6 alpha-Receptor/gp130 Complex
Science, 300, 2003
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2ARW
 | | The solution structure of the membrane proximal cytokine receptor domain of the human interleukin-6 receptor | | 分子名称: | Interleukin-6 receptor alpha chain | | 著者 | Hecht, O, Dingley, A.J, Schwantner, A, Ozbek, S, Rose-John, S, Grotzinger, J. | | 登録日 | 2005-08-22 | | 公開日 | 2006-09-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the membrane-proximal cytokine receptor domain of the human interleukin-6 receptor
Biol.Chem., 387, 2006
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