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PDB: 58 件
1MDU
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Crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (GS-1)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
著者Dawson, J.F, Sablin, E.P, Spudich, J.A, Fletterick, R.J.
登録日2002-08-07
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of an F-actin trimer disrupted by gelsolin and implications for the mechanism of severing
J.Biol.Chem., 278, 2003
4PKI
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Complex of ATP-actin With the C-terminal Actin-Binding Domain of Tropomodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Rao, J.N, Dominguez, R.
登録日2014-05-14
公開日2014-07-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Actin cytoskeleton. Mechanism of actin filament pointed-end capping by tropomodulin.
Science, 345, 2014
1EQY
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BU of 1eqy by Molmil
COMPLEX BETWEEN RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ALPHA ACTIN, CALCIUM ION, ...
著者McLaughlin, P.J, Gooch, J.T, Mannherz, H.G, Weeds, A.G.
登録日2000-04-06
公開日2000-05-03
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of gelsolin segment 1-actin complex and the mechanism of filament severing.
Nature, 364, 1993
3A5N
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BU of 3a5n by Molmil
Crystal Structure of a Dictyostelium P109A Ca2+-Actin in Complex with Human Gelsolin Segment 1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Gelsolin, ...
著者Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
登録日2009-08-09
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
5UBO
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BU of 5ubo by Molmil
Mical-oxidized Actin complex with Gelsolin Segment 1
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Grintsevich, E.E, Sawaya, M.R, Reisler, E.
登録日2016-12-21
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Catastrophic disassembly of actin filaments via Mical-mediated oxidation.
Nat Commun, 8, 2017
1C0F
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BU of 1c0f by Molmil
CRYSTAL STRUCTURE OF DICTYOSTELIUM CAATP-ACTIN IN COMPLEX WITH GELSOLIN SEGMENT 1
分子名称: ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
著者Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T.
登録日1999-07-16
公開日2000-03-01
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras
J.Mol.Biol., 296, 2000
1DEJ
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BU of 1dej by Molmil
CRYSTAL STRUCTURE OF A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 646: Q228K/T229A/A230Y/A231K/S232E/E360H) IN COMPLEX WITH HUMAN GELSOLIN SEGMENT 1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHIMERIC ACTIN, ...
著者Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T.
登録日1999-11-15
公開日2000-03-01
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras.
J.Mol.Biol., 296, 2000
4Z94
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Actin Complex With a Chimera of Tropomodulin-1 and Leiomodin-1 Actin-Binding Site 2
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Rebowski, G, Boczkowska, M, Dominguez, R.
登録日2015-04-09
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015
3A5O
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Crystal Structure of a Dictyostelium P109I Ca2+-Actin in Complex with Human Gelsolin Segment 1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Gelsolin, ...
著者Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
登録日2009-08-09
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
3A5M
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BU of 3a5m by Molmil
Crystal Structure of a Dictyostelium P109I Mg2+-Actin in Complex with Human Gelsolin Segment 1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Gelsolin, ...
著者Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
登録日2009-08-09
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
3A5L
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BU of 3a5l by Molmil
Crystal Structure of a Dictyostelium P109A Mg2+-Actin in Complex with Human Gelsolin Segment 1
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Gelsolin, ...
著者Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
登録日2009-08-09
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
2FH2
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BU of 2fh2 by Molmil
C-terminal half of gelsolin soaked in EGTA at pH 4.5
分子名称: CALCIUM ION, Gelsolin
著者Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C.
登録日2005-12-23
公開日2006-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
1P8Z
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BU of 1p8z by Molmil
Complex Between Rabbit Muscle alpha-Actin: Human Gelsolin Residues Val26-Glu156
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Irobi, E, Burtnick, L.D, Robinson, R.C.
登録日2003-05-08
公開日2003-10-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献From the First to the second domain of gelsolin: A common path on the surface of actin?
FEBS lett., 552, 2003
4S10
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BU of 4s10 by Molmil
Gelsolin nanobody shielding mutant plasma gelsolin from furin proteolysis
分子名称: CALCIUM ION, GELSOLIN NANOBODY, Gelsolin
著者Wongsantichon, J, Robinson, R.C, Gettemans, J.
登録日2015-01-07
公開日2015-06-03
実験手法X-RAY DIFFRACTION (2.614 Å)
主引用文献An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model.
Hum.Mol.Genet., 24, 2015
5ZZ0
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BU of 5zz0 by Molmil
HUMAN GELSOLIN FROM RESIDUES GLU28 TO ARG161 WITH CALCIUM
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, Gelsolin
著者Sharma, P, Badmalia, M, Yadav, S.P.S, Singh, S.
登録日2018-05-29
公開日2019-06-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.635 Å)
主引用文献Bonsai Gelsolin Survives Heat Induced Denaturation by Forming beta-Amyloids which Leach Out Functional Monomer.
Sci Rep, 8, 2018
6Q9R
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BU of 6q9r by Molmil
Crystal structure of the pathological N184K variant of calcium-free human gelsolin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Scalone, E, Boni, F, Milani, M, Eloise, M, de Rosa, M.
登録日2018-12-18
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
2FH3
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BU of 2fh3 by Molmil
C-terminal half of gelsolin soaked in low calcium at pH 8
分子名称: CALCIUM ION, Gelsolin
著者Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C.
登録日2005-12-23
公開日2006-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
6JCO
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BU of 6jco by Molmil
Crystal structure of calcium free human gelsolin amyloid mutant D187N
分子名称: Gelsolin
著者Zorgati, H, Robinson, R.C.
登録日2019-01-29
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献The role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Proc.Natl.Acad.Sci.USA, 116, 2019
6JEH
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BU of 6jeh by Molmil
Crystal structure of calcium free human gelsolin amyloid mutant D187Y
分子名称: Gelsolin
著者Zorgati, H, Robinson, R.C.
登録日2019-02-05
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Proc.Natl.Acad.Sci.USA, 116, 2019
6JEG
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BU of 6jeg by Molmil
Crystal structure of calcium free human gelsolin amyloid mutant G167R
分子名称: GLYCEROL, Gelsolin
著者Zorgati, H, Robinson, R.C.
登録日2019-02-05
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.975 Å)
主引用文献The role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Proc.Natl.Acad.Sci.USA, 116, 2019
1H1V
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BU of 1h1v by Molmil
gelsolin G4-G6/actin complex
分子名称: ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
著者Choe, H, Burtnick, L.D, Mejillano, M, Yin, H.L, Robinson, R.C, Choe, S.
登録日2002-07-23
公開日2003-01-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The Calcium Activation of Gelsolin:Insights from the 3A Structure of the G4-G6/Actin Complex
J.Mol.Biol., 324, 2002
7P2B
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BU of 7p2b by Molmil
Crystal structure of human gelsolin amyloid mutant A551P
分子名称: CHLORIDE ION, GLYCEROL, Gelsolin, ...
著者Bollati, M, de Rosa, M.
登録日2021-07-05
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation.
Comput Struct Biotechnol J, 19, 2021
3FFK
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BU of 3ffk by Molmil
Crystal structure of human Gelsolin domains G1-G3 bound to Actin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, actin, ...
著者Chumnarnsilpa, S, Robinson, R.C, Burtnick, L.D.
登録日2008-12-03
公開日2009-10-06
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin.
Proc.Natl.Acad.Sci.USA, 106, 2009
2FH4
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C-terminal half of gelsolin soaked in EGTA at pH 8
分子名称: Gelsolin
著者Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C.
登録日2005-12-23
公開日2006-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
3FFN
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Crystal structure of calcium-free human gelsolin
分子名称: Gelsolin
著者Chumnarnsilpa, S, Robinson, R.C, Burtnick, L.D.
登録日2008-12-04
公開日2009-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin.
Proc.Natl.Acad.Sci.USA, 106, 2009

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