1MDU

Crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (GS-1)

Summary for 1MDU

Entry DOI	10.2210/pdb1mdu/pdb
Descriptor	gelsolin precursor, a-actin, CALCIUM ION, ... (6 entities in total)
Functional Keywords	gelsolin precursor, a-actin, adenosine-5'-triphosphate, 2-amino-2-hydroxymethyl-propane-1, 3-diol, structural protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton: P06396 Isoform 2: Cytoplasm, cytoskeleton. Isoform 1: Secreted: P68139
Total number of polymer chains	4
Total formula weight	113780.66
Authors	Dawson, J.F.,Sablin, E.P.,Spudich, J.A.,Fletterick, R.J. (deposition date: 2002-08-07, release date: 2003-01-07, Last modification date: 2011-07-13)
Primary citation	Dawson, J.F.,Sablin, E.P.,Spudich, J.A.,Fletterick, R.J. Structure of an F-actin trimer disrupted by gelsolin and implications for the mechanism of severing J.Biol.Chem., 278:1229-1238, 2003 Cited by PubMed: 12356759 DOI: 10.1074/jbc.M209160200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation