1MDU
Crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (GS-1)
Summary for 1MDU
Entry DOI | 10.2210/pdb1mdu/pdb |
Descriptor | gelsolin precursor, a-actin, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | gelsolin precursor, a-actin, adenosine-5'-triphosphate, 2-amino-2-hydroxymethyl-propane-1, 3-diol, structural protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton: P06396 Isoform 2: Cytoplasm, cytoskeleton. Isoform 1: Secreted: P68139 |
Total number of polymer chains | 4 |
Total formula weight | 113780.66 |
Authors | Dawson, J.F.,Sablin, E.P.,Spudich, J.A.,Fletterick, R.J. (deposition date: 2002-08-07, release date: 2003-01-07, Last modification date: 2011-07-13) |
Primary citation | Dawson, J.F.,Sablin, E.P.,Spudich, J.A.,Fletterick, R.J. Structure of an F-actin trimer disrupted by gelsolin and implications for the mechanism of severing J.Biol.Chem., 278:1229-1238, 2003 Cited by PubMed: 12356759DOI: 10.1074/jbc.M209160200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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