3A5M

Crystal Structure of a Dictyostelium P109I Mg2+-Actin in Complex with Human Gelsolin Segment 1

Summary for 3A5M

Entry DOI	10.2210/pdb3a5m/pdb
Related	1C0F 3A5L 3A5N 3A5O
Descriptor	Gelsolin, Major actin, CALCIUM ION, ... (6 entities in total)
Functional Keywords	actin, adp, hydrolysis, actin capping, actin-binding, cytoskeleton, atp-binding, nucleotide-binding, structural protein, contractile protein
Biological source	HOMO SAPIENS (human) More
Cellular location	Isoform 2: Cytoplasm, cytoskeleton. Isoform 1: Secreted: P06396 Cytoplasm, cytoskeleton: P07830
Total number of polymer chains	2
Total formula weight	56290.93
Authors	Murakami, K.,Yasunaga, T.,Noguchi, T.Q.,Uyeda, T.Q.,Wakabayashi, T. (deposition date: 2009-08-09, release date: 2010-10-27, Last modification date: 2023-11-01)
Primary citation	Murakami, K.,Yasunaga, T.,Noguchi, T.Q.P.,Gomibuchi, Y.,Ngo, K.X.,Uyeda, T.Q.P.,Wakabayashi, T. Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release Cell(Cambridge,Mass.), 143:275-287, 2010 Cited by PubMed: 20946985 DOI: 10.1016/j.cell.2010.09.034 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation