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PDB: 194 件

4V88
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The structure of the eukaryotic ribosome at 3.0 A resolution.
分子名称: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ...
著者Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M.
登録日2011-10-11
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of the eukaryotic ribosome at 3.0 angstrom resolution.
Science, 334, 2011
7OSA
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BU of 7osa by Molmil
Pre-translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligands
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
著者Djumagulov, M, Jenner, L, Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2021-06-08
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Accuracy mechanism of eukaryotic ribosome translocation.
Nature, 600, 2021
7OSM
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Intermediate translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligands
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
著者Djumagulov, M, Jenner, L, Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2021-06-09
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Accuracy mechanism of eukaryotic ribosome translocation.
Nature, 600, 2021
4U4Q
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Crystal structure of Homoharringtonine bound to the yeast 80S ribosome
分子名称: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-24
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U52
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BU of 4u52 by Molmil
Crystal structure of Nagilactone C bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-24
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4U
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BU of 4u4u by Molmil
Crystal structure of Lycorine bound to the yeast 80S ribosome
分子名称: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-24
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U3M
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Crystal structure of Anisomycin bound to the yeast 80S ribosome
分子名称: 18S rRNA, 25s rRNA, 40S ribosomal protein S0-A, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-22
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
6YLG
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BU of 6ylg by Molmil
Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Kater, L, Beckmann, R.
登録日2020-04-07
公開日2020-07-29
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
5TBW
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BU of 5tbw by Molmil
Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Konst, Z.A, Szklarski, A.R, Pellegrino, S, Michalak, S.E, Meyer, M, Zanette, C, Cencic, R, Nam, S, Horne, D.A, Pelletier, J, Mobley, D.L, Yusupova, G, Yusupov, M, Vanderwal, C.D.
登録日2016-09-13
公開日2017-07-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
7NAC
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BU of 7nac by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model
分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-21
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R7A
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BU of 7r7a by Molmil
State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model
分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-24
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7MPI
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Stm1 bound vacant 80S structure isolated from cbf5-D95A
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Rai, J, Zhao, Y, Li, H.
登録日2021-05-04
公開日2022-05-11
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
7N8B
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Cycloheximide bound vacant 80S structure isolated from cbf5-D95A
分子名称: 18S RIBOSOMAL RNA, 25S, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
著者Rai, J, Zhao, Y, Li, H.
登録日2021-06-14
公開日2022-05-11
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
5H4P
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Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Ma, C, Wu, S, Li, N, Chen, Y, Yan, K, Li, Z, Zheng, L, Lei, J, Woolford, J.L, Gao, N.
登録日2016-11-01
公開日2017-01-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
3JCT
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BU of 3jct by Molmil
Cryo-em structure of eukaryotic pre-60S ribosomal subunits
分子名称: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N.
登録日2016-03-09
公開日2016-06-01
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes
Nature, 534, 2016
7OHQ
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BU of 7ohq by Molmil
Nog1-TAP associated immature ribosomal particle population C from S. cerevisiae
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Milkereit, P, Poell, G.
登録日2021-05-11
公開日2021-11-03
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OF1
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BU of 7of1 by Molmil
Nog1-TAP associated immature ribosomal particle population A from S. cerevisiae
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Milkereit, P, Poell, G.
登録日2021-05-04
公開日2021-11-03
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
5FCJ
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BU of 5fcj by Molmil
Structure of the anisomycin-containing uL3 W255C mutant 80S yeast ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M.
登録日2015-12-15
公開日2016-05-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016
8BIP
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BU of 8bip by Molmil
Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R.
登録日2022-11-02
公開日2023-02-08
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.
Plos Biol., 21, 2023
5DGV
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BU of 5dgv by Molmil
Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog
分子名称: 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
登録日2015-08-28
公開日2016-12-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
6QIK
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BU of 6qik by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Kargas, V, Warren, A.J.
登録日2019-01-20
公開日2019-06-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6Q8Y
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Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Tesina, P, Heckel, E, Cheng, J, Buschauer, R, Kater, L, Berninghausen, O, Becker, T, Beckmann, R.
登録日2018-12-16
公開日2019-03-13
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the 80S ribosome-Xrn1 nuclease complex.
Nat.Struct.Mol.Biol., 26, 2019
5I4L
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BU of 5i4l by Molmil
Crystal structure of Amicoumacin A bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Prokhorova, I.V, Yusupova, G, Yusupov, M.
登録日2016-02-12
公開日2016-06-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome.
Sci Rep, 6, 2016
4U6F
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BU of 4u6f by Molmil
Crystal structure of T-2 toxin bound to the yeast 80S ribosome
分子名称: 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-28
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
6YLH
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BU of 6ylh by Molmil
Rix1-Rea1 pre-60S particle - full composite structure
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Kater, L, Beckmann, R.
登録日2020-04-07
公開日2020-07-29
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020

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件を2024-06-26に公開中

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