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PDB: 172 件

3K0R
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Cryogenic structure of CypA mutant Arg55Lys
分子名称: Cyclophilin A
著者Fraser, J.S, Alber, T.
登録日2009-09-25
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.424 Å)
主引用文献Hidden alternative structures of proline isomerase essential for catalysis.
Nature, 462, 2009
6U5G
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MicroED structure of a FIB-milled CypA Crystal
分子名称: Peptidyl-prolyl cis-trans isomerase A
著者Wolff, A.M, Martynowycz, M.W, Zhao, W, Gonen, T, Fraser, J.S, Thompson, M.C.
登録日2019-08-27
公開日2020-01-29
最終更新日2023-10-11
実験手法ELECTRON CRYSTALLOGRAPHY (2.5 Å)
主引用文献Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals
Iucrj, 7, 2020
1AWS
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SECYPA COMPLEXED WITH HAGPIA (PSEUDO-SYMMETRIC MONOMER)
分子名称: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
著者Vajdos, F.F.
登録日1997-10-04
公開日1998-03-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1AWT
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SECYPA COMPLEXED WITH HAGPIA
分子名称: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
著者Vajdos, F.F.
登録日1997-10-05
公開日1998-03-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1ZKF
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Cyrstal Structure of Human Cyclophilin-A in Complex with suc-AGPF-pNA
分子名称: Peptidyl-prolyl cis-trans isomerase A, Suc-ALA-GLY-PRO-PHE-pNA
著者Eisenmesser, E.Z, Thai, V, Pozharski, E, Kern, D.
登録日2005-05-02
公開日2006-04-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Mechanistic Insights of Cyclophilin-A from X-Ray Cyrstallographic and Nuclear Magnet Resonance Investigations
To be Published
1M63
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Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes
分子名称: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CYCLOSPORIN A, ...
著者Huai, Q, Kim, H.-Y, Liu, Y, Zhao, Y, Mondragon, A, Liu, J.O, Ke, H.
登録日2002-07-12
公開日2002-09-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes
Proc.Natl.Acad.Sci.USA, 99, 2002
1MF8
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Crystal Structure of human calcineurin complexed with cyclosporin A and human cyclophilin
分子名称: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CALMODULIN-DEPENDENT CALCINEURIN A SUBUNIT, ...
著者Jin, L, Harrison, S.C.
登録日2002-08-09
公開日2002-10-16
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human Calcineurin Complexed with Cyclosporin a and Human Cyclophilin
Proc.Natl.Acad.Sci.USA, 99, 2002
7UPN
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Maedi visna virus Vif in complex with CypA and E3 ubiquitin ligase
分子名称: Elongin-B, Elongin-C, Peptidyl-prolyl cis-trans isomerase A, ...
著者Hu, Y, Xiong, Y.
登録日2022-04-16
公開日2023-01-25
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for recruitment of host CypA and E3 ubiquitin ligase by maedi-visna virus Vif.
Sci Adv, 9, 2023
7N9X
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CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
分子名称: Capsid protein, Nanobody, Peptidyl-prolyl cis-trans isomerase A
著者Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y.
登録日2021-06-18
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.511 Å)
主引用文献CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
To Be Published
6Y9W
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Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,8)
分子名称: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
著者Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
登録日2020-03-10
公開日2020-08-19
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6Y9X
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Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,7)
分子名称: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
著者Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
登録日2020-03-10
公開日2020-08-19
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6Y9Z
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Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,9)
分子名称: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
著者Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
登録日2020-03-10
公開日2020-08-19
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6ZDJ
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Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,10)
分子名称: Gag protein, Peptidyl-prolyl cis-trans isomerase A
著者Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
登録日2020-06-14
公開日2020-08-19
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6Y9Y
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Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-7,13)
分子名称: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
著者Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
登録日2020-03-10
公開日2020-08-19
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6Y9V
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Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-8,13)
分子名称: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
著者Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
登録日2020-03-10
公開日2020-08-19
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
5FJB
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Cyclophilin A Stabilize HIV-1 Capsid through a Novel Non- canonical Binding Site
分子名称: GAG POLYPROTEIN, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Liu, C, Perilla, J.R, Ning, J, Lu, M, Hou, G, Ramalhu, R, Bedwell, G.J, Ahn, J, Shi, J, Gronenborn, A.M, Prevelige Jr, P.E, Rousso, I, Aiken, C, Polenova, T, Schulten, K, Zhang, P.
登録日2015-10-07
公開日2016-03-16
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Cyclophilin a Stabilizes the HIV-1 Capsid Through a Novel Non-Canonical Binding Site.
Nat.Commun., 7, 2016
2MZU
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Extending the eNOE data set of large proteins by evaluation of NOEs with unresolved diagonals
分子名称: Peptidyl-prolyl cis-trans isomerase A
著者Chi, C.N, Strotz, D, Riek, R, Voegeli, B.
登録日2015-02-24
公開日2015-04-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Extending the eNOE data set of large proteins by evaluation of NOEs with unresolved diagonals.
J.Biomol.Nmr, 62, 2015
1OCA
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HUMAN CYCLOPHILIN A, UNLIGATED, NMR, 20 STRUCTURES
分子名称: CYCLOPHILIN A
著者Ottiger, M, Zerbe, O, Guntert, P, Wuthrich, K.
登録日1997-07-07
公開日1997-11-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The NMR solution conformation of unligated human cyclophilin A.
J.Mol.Biol., 272, 1997
2N0T
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Structural ensemble of the enzyme cyclophilin reveals an orchestrated mode of action at atomic resolution
分子名称: Peptidyl-prolyl cis-trans isomerase A
著者Chi, C.N, Voegeli, B, Bibow, S, Strotz, D, Orts, J, Guntert, P, Riek, R.
登録日2015-03-13
公開日2015-08-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A Structural Ensemble for the Enzyme Cyclophilin Reveals an Orchestrated Mode of Action at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 54, 2015
2MS4
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Cyclophilin a complexed with a fragment of crk-ii
分子名称: Peptide, Peptidyl-prolyl cis-trans isomerase A
著者Jankowski, W, Saleh, T, Rossi, P, Kalodimos, C.
登録日2014-07-22
公開日2015-09-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway.
Nat.Chem.Biol., 12, 2016
3CYS
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DETERMINATION OF THE NMR SOLUTION STRUCTURE OF THE CYCLOPHILIN A-CYCLOSPORIN A COMPLEX
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Spitzfaden, C, Braun, W, Wider, G, Widmer, H, Wuthrich, K.
登録日1994-02-28
公開日1994-08-31
最終更新日2017-11-01
実験手法SOLUTION NMR
主引用文献Determination of the NMR Solution Structure of the Cyclophilin A-Cyclosporin a Complex.
J.Biomol.NMR, 4, 1994
7TA8
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NMR structure of crosslinked cyclophilin A
分子名称: Peptidyl-prolyl cis-trans isomerase A
著者Lu, M, Toptygin, D, Xiang, Y, Shi, Y, Schwieters, C.D, Lipinski, E.C, Ahn, J, Byeon, I.-J.L, Gronenborn, A.M.
登録日2021-12-20
公開日2022-06-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Magic of Linking Rings: Discovery of a Unique Photoinduced Fluorescent Protein Crosslink.
J.Am.Chem.Soc., 144, 2022

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