6Y9Y

Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-7,13)

Summary for 6Y9Y

Entry DOI	10.2210/pdb6y9y/pdb
EMDB information	10741
Descriptor	Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A (2 entities in total)
Functional Keywords	hiv, capsid, hexamer, helical assembly, curvature, viral protein
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	13
Total formula weight	312278.44
Authors	Ni, T.,Gerard, S.,Zhao, G.,Ning, J.,Zhang, P. (deposition date: 2020-03-10, release date: 2020-08-19, Last modification date: 2021-02-10)
Primary citation	Ni, T.,Gerard, S.,Zhao, G.,Dent, K.,Ning, J.,Zhou, J.,Shi, J.,Anderson-Daniels, J.,Li, W.,Jang, S.,Engelman, A.N.,Aiken, C.,Zhang, P. Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27:855-862, 2020 Cited by PubMed: 32747784 DOI: 10.1038/s41594-020-0467-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (6.1 Å)

Structure validation