6DBJ
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![BU of 6dbj by Molmil](/molmil-images/mine/6dbj) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates | 分子名称: | CALCIUM ION, Forward stand of RSS signal end, Forward strand of coding flank, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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4FEC
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![BU of 4fec by Molmil](/molmil-images/mine/4fec) | Crystal Structure of Htt36Q3H | 分子名称: | Maltose-binding periplasmic protein,Huntingtin, ZINC ION | 著者 | Kim, M. | 登録日 | 2012-05-30 | 公開日 | 2013-03-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Beta conformation of polyglutamine track revealed by a crystal structure of Huntingtin N-terminal region with insertion of three histidine residues. Prion, 7, 2013
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8JI0
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![BU of 8ji0 by Molmil](/molmil-images/mine/8ji0) | |
8JXS
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![BU of 8jxs by Molmil](/molmil-images/mine/8jxs) | Structure of nanobody-bound DRD1_PF-6142 complex | 分子名称: | 4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine, D(1A) dopamine receptor, Fab 8D3 heavy chain, ... | 著者 | Zhuang, Y, Xu, Y, Fan, L, Wang, S, Xu, H.E. | 登録日 | 2023-07-01 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of psychedelic LSD recognition at dopamine D 1 receptor. Neuron, 2024
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9CET
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![BU of 9cet by Molmil](/molmil-images/mine/9cet) | Guillardia theta Fanzor (GtFz) State 3 | 分子名称: | DNA (28-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*TP*AP*AP*AP*GP*GP*CP*CP*CP*CP*GP*GP*G)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | 著者 | Xu, P, Saito, M, Zhang, F. | 登録日 | 2024-06-27 | 公開日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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5Y2G
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![BU of 5y2g by Molmil](/molmil-images/mine/5y2g) | Structure of MBP tagged GBS CAMP | 分子名称: | Maltose-binding periplasmic protein,Protein B, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Jin, T, Li, Y. | 登録日 | 2017-07-25 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure determination of the CAMP factor of Streptococcus agalactiae with the aid of an MBP tag and insights into membrane-surface attachment. Acta Crystallogr D Struct Biol, 75, 2019
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7W3Z
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![BU of 7w3z by Molmil](/molmil-images/mine/7w3z) | Cryo-EM Structure of Human Gastrin Releasing Peptide Receptor in complex with the agonist Gastrin Releasing Peptide and Gq heterotrimers | 分子名称: | Gastrin Releasing Peptide PRGNHWAVGHLM(NH2), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhan, Y, Peng, S, Zhang, H. | 登録日 | 2021-11-26 | 公開日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy. Proc.Natl.Acad.Sci.USA, 120, 2023
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7W40
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![BU of 7w40 by Molmil](/molmil-images/mine/7w40) | Cryo-EM Structure of Human Gastrin Releasing Peptide Receptor in complex with the agonist Bombesin (6-14) [D-Phe6, beta-Ala11, Phe13, Nle14] and Gq heterotrimers | 分子名称: | Bombesin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhan, Y, Peng, S, Zhang, H. | 登録日 | 2021-11-26 | 公開日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy. Proc.Natl.Acad.Sci.USA, 120, 2023
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6YSN
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![BU of 6ysn by Molmil](/molmil-images/mine/6ysn) | Human TRPC5 in complex with Pico145 (HC-608) | 分子名称: | 7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)-8-[3-(trifluoromethyloxy)phenoxy]purine-2,6-dione, Maltose/maltodextrin-binding periplasmic protein,Short transient receptor potential channel 5 | 著者 | Wright, D.J, Johnson, R.M, Muench, S.P, Bon, R.S. | 登録日 | 2020-04-22 | 公開日 | 2020-12-02 | 最終更新日 | 2020-12-09 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site. Commun Biol, 3, 2020
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4FE8
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![BU of 4fe8 by Molmil](/molmil-images/mine/4fe8) | Crystal Structure of Htt36Q3H-EX1-X1-C1(Alpha) | 分子名称: | Maltose-binding periplasmic protein,Huntingtin, ZINC ION | 著者 | Kim, M. | 登録日 | 2012-05-29 | 公開日 | 2013-03-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Beta conformation of polyglutamine track revealed by a crystal structure of Huntingtin N-terminal region with insertion of three histidine residues. Prion, 7, 2013
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2ZXT
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![BU of 2zxt by Molmil](/molmil-images/mine/2zxt) | Crystal structure of Tim40/MIA40, a disulfide relay system in mitochondria, solved as MBP fusion protein | 分子名称: | Maltose-binding periplasmic protein, LINKER, Mitochondrial intermembrane space import and assembly protein 40, ... | 著者 | Kawano, S, Momose, T, Watanabe, N, Endo, T. | 登録日 | 2009-01-07 | 公開日 | 2009-08-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane space. Proc.Natl.Acad.Sci.USA, 106, 2009
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8XB2
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![BU of 8xb2 by Molmil](/molmil-images/mine/8xb2) | Structure of radafaxine-bound state of the human Norepinephrine Transporter | 分子名称: | (2~{S},3~{S})-2-(3-chlorophenyl)-3,5,5-trimethyl-morpholin-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, GFP-MBP-solute carrier family 6 member 2,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter | 著者 | Wu, J.X, Ji, W.M. | 登録日 | 2023-12-05 | 公開日 | 2024-07-10 | 最終更新日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Substrate binding and inhibition mechanism of norepinephrine transporter. Nature, 2024
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4BL8
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![BU of 4bl8 by Molmil](/molmil-images/mine/4bl8) | Crystal structure of full-length human Suppressor of fused (SUFU) | 分子名称: | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Karlstrom, M, Finta, C, Cherry, A.L, Toftgard, R, Jovine, L. | 登録日 | 2013-05-02 | 公開日 | 2013-11-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | 主引用文献 | Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation Acta Crystallogr.,Sect.D, 69, 2013
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3SEV
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![BU of 3sev by Molmil](/molmil-images/mine/3sev) | Zn-mediated Trimer of Maltose-binding Protein E310H/K314H by Synthetic Symmetrization | 分子名称: | CHLORIDE ION, Maltose-binding periplasmic protein, ZINC ION, ... | 著者 | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-11 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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8VG0
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![BU of 8vg0 by Molmil](/molmil-images/mine/8vg0) | |
7MN6
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![BU of 7mn6 by Molmil](/molmil-images/mine/7mn6) | Structure of the HER2 S310F/HER3/NRG1b Heterodimer Extracellular Domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... | 著者 | Diwanji, D, Trenker, R, Verba, K.A, Jura, N. | 登録日 | 2021-04-30 | 公開日 | 2021-10-27 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Structures of the HER2-HER3-NRG1 beta complex reveal a dynamic dimer interface. Nature, 600, 2021
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3EF7
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![BU of 3ef7 by Molmil](/molmil-images/mine/3ef7) | |
3PUY
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![BU of 3puy by Molmil](/molmil-images/mine/3puy) | |
3PV0
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![BU of 3pv0 by Molmil](/molmil-images/mine/3pv0) | |
5LEL
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![BU of 5lel by Molmil](/molmil-images/mine/5lel) | Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_10_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein | 分子名称: | DD_Off7_10_3G124, Green fluorescent protein, Maltose-binding periplasmic protein | 著者 | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | 登録日 | 2016-06-30 | 公開日 | 2017-11-15 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Rigidly connected multispecific artificial binders with adjustable geometries. Sci Rep, 7, 2017
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6M4W
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![BU of 6m4w by Molmil](/molmil-images/mine/6m4w) | Crystal structure of MBP fused split FKBP-FRB T2098L mutant in complex with rapamycin | 分子名称: | GLYCEROL, Peptidyl-prolyl cis-trans isomerase FKBP1A, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, ... | 著者 | Kikuchi, M, Wu, D, Inoue, T, Umehara, T. | 登録日 | 2020-03-09 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Rational design and implementation of a chemically inducible heterotrimerization system. Nat.Methods, 17, 2020
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9CF2
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![BU of 9cf2 by Molmil](/molmil-images/mine/9cf2) | Parasitella parasitica Fanzor (PpFz) State 3 | 分子名称: | DNA (26-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | 著者 | Xu, P, Saito, M, Zhang, F. | 登録日 | 2024-06-27 | 公開日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor. Cell, 2024
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5JQE
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![BU of 5jqe by Molmil](/molmil-images/mine/5jqe) | Crystal structure of caspase8 tDED | 分子名称: | Sugar ABC transporter substrate-binding protein,Caspase-8 chimera | 著者 | Fu, T, Li, Y, Lu, A, Wu, H. | 登録日 | 2016-05-04 | 公開日 | 2016-10-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.157 Å) | 主引用文献 | Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex. Mol. Cell, 64, 2016
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5W1C
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![BU of 5w1c by Molmil](/molmil-images/mine/5w1c) | Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with cytidine | 分子名称: | 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, CALCIUM ION, DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*TP*GP*AP*AP*C)-3'), ... | 著者 | Qiao, Q, Wang, L, Wu, H. | 登録日 | 2017-06-02 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | AID Recognizes Structured DNA for Class Switch Recombination. Mol. Cell, 67, 2017
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7P1G
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![BU of 7p1g by Molmil](/molmil-images/mine/7p1g) | Structure of the P. aeruginosa ExoY-F-actin complex | 分子名称: | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | 著者 | Belyy, A, Merino, F, Raunser, S. | 登録日 | 2021-07-01 | 公開日 | 2021-11-17 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens. Nat Commun, 12, 2021
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