4LCY
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3SKO
| Crystal structure of the HLA-B8-A66-FLR, mutant A66 of the HLA B8 | 分子名称: | Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J. | 登録日 | 2011-06-22 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. J.Immunol., 188, 2012
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2VLL
| The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain | 分子名称: | BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y. | 登録日 | 2008-01-15 | 公開日 | 2008-01-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain Immunity, 28, 2008
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1ZHK
| Crystal structure of HLA-B*3501 presenting 13-mer EBV antigen LPEPLPQGQLTAY | 分子名称: | Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, HLA class I histocompatibility antigen, ... | 著者 | Tynan, F.E, Borg, N.A, Miles, J.J, Beddoe, T, El-Hassen, D, Silins, S.L, van Zuylen, W.J, Purcell, A.W, Kjer-Nielsen, L, McCluskey, J, Burrows, S.R, Rossjohn, J. | 登録日 | 2005-04-26 | 公開日 | 2005-05-17 | 最終更新日 | 2014-04-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance J.Biol.Chem., 280, 2005
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6V2Q
| HLA-B*57:03 presenting the peptide LSSPVTKSF | 分子名称: | ACETATE ION, Beta-2-microglobulin, HLA-B alpha chain (B*5703GB), ... | 著者 | Maclachlan, B, Rossjohn, J, Vivian, J.P. | 登録日 | 2019-11-25 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proc.Natl.Acad.Sci.USA, 117, 2020
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3PWN
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3BGM
| Crystal Structure of PKD2 Phosphopeptide Bound to Human Class I MHC HLA-A2 | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Mohammed, F, Cobbold, M, Zarling, A.L, Salim, M, Barrett-Wilt, G.A, Shabanowitz, J, Hunt, D.F, Engelhard, V.H, Willcox, B.E. | 登録日 | 2007-11-27 | 公開日 | 2008-10-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self Nat.Immunol., 9, 2008
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3MYZ
| Protein induced photophysical changes to the amyloid indicator dye, thioflavin T | 分子名称: | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, ACETATE ION, Beta-2-microglobulin, ... | 著者 | Wolfe, L.S, Calabrese, M.F, Nath, A, Blaho, D.V, Miranker, A.D, Xiong, Y. | 登録日 | 2010-05-11 | 公開日 | 2010-09-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Protein-induced photophysical changes to the amyloid indicator dye thioflavin T. Proc.Natl.Acad.Sci.USA, 107, 2010
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6TDQ
| Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GM dipeptide in the A pocket and one GM dipeptide in the F pocket. | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ... | 著者 | Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. | 登録日 | 2019-11-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun, 11, 2020
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6K7T
| Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1--human beta-2 microglobulin | 分子名称: | Beta-2-microglobulin, HeV1, MHC class I antigen | 著者 | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | 登録日 | 2019-06-08 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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3KPM
| Crystal Structure of HLA B*4402 in complex with EEYLKAWTF, a mimotope | 分子名称: | Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | 登録日 | 2009-11-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
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5DEF
| Crystal structure of B*27:04 complex bound to the pVIPR peptide | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | 著者 | Loll, B, Fabian, H, Huser, H, Hee, C.S, Uchanska-Ziegler, B, Ziegler, A. | 登録日 | 2015-08-25 | 公開日 | 2015-11-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis. Arthritis Rheumatol, 68, 2016
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4G8I
| Crystal Structure of HLA B2705-KK10-L6M | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, Gag protein, ... | 著者 | Gras, S, Wilmann, P.G, Rossjohn, J. | 登録日 | 2012-07-23 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells. Immunity, 38, 2013
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2HN7
| HLA-A*1101 in complex with HBV peptide homologue | 分子名称: | Beta-2-microglobulin, DNA polymerase PEPTIDE HOMOLOGUE, HLA class I histocompatibility antigen, ... | 著者 | Blicher, T. | 登録日 | 2006-07-12 | 公開日 | 2006-11-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue. Acta Crystallogr.,Sect.F, 62, 2006
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1M6O
| Crystal Structure of HLA B*4402 in complex with HLA DPA*0201 peptide | 分子名称: | Beta-2-microglobulin, HLA DPA*0201 peptide, HLA class I histocompatibility antigen, ... | 著者 | Macdonald, W.A, Purcell, A.W, Williams, D.S, Mifsud, N.A, Ely, L.K, Gorman, J.J, Clements, C.S, Kjer-Nielsen, L, Koelle, D.M, Brooks, A.G, Lovrecz, G.O, Lu, L, Rossjohn, J, McCluskey, J. | 登録日 | 2002-07-17 | 公開日 | 2003-09-02 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. J.Exp.Med., 198, 2003
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7R7Y
| Crystal structure of HLA-B*5701 complex with an HIV-1 Gag-derived epitope QW9 S3T variant | 分子名称: | Beta-2-microglobulin, GLN-ALA-THR-GLN-GLU-VAL-LYS-ASN-TRP, GLYCEROL, ... | 著者 | Li, X.L, Ng, R, Tan, K.M, Walker, B.D, Wang, J.H. | 登録日 | 2021-06-25 | 公開日 | 2022-06-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide. Nat Commun, 14, 2023
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6EI2
| Crystal Structure of HLA-A68 presenting a C-terminally extended peptide | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CADMIUM ION, ... | 著者 | Picaud, S, Guillaume, P, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gfeller, D, Filippakopoulos, P. | 登録日 | 2017-09-16 | 公開日 | 2017-10-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Crystal Structure of HLA-A68 presenting a C-terminally extended peptide To Be Published
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5WMO
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3V5H
| HLA-A2.1 KVAEIVHFL | 分子名称: | Beta-2-microglobulin, GLYCEROL, HIV-based altered-peptide ligand KVAEIVHFL, ... | 著者 | Collins, E.J, Lee, H.Y. | 登録日 | 2011-12-16 | 公開日 | 2012-12-05 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Prediction of immunogenicity of altered-peptide ligands for HIV therapy To be Published
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7UM2
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5C0J
| HLA-A02 carrying RQFGPDWIVA | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CALCIUM ION, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2015-06-12 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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5VWH
| HLA-B*58:01 presenting LSSPVTKSW | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ... | 著者 | Pymm, P, Rossjohn, J, Vivian, J.P. | 登録日 | 2017-05-21 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | 主引用文献 | HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
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3PWL
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4WJ5
| Structure of HLA-A2 in complex with an altered peptide ligands based on Mart-1 variant epitope | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Celie, P.H.N, Rodenko, B, Ovaa, H. | 登録日 | 2014-09-29 | 公開日 | 2014-10-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Altered Peptide Ligands Revisited: Vaccine Design through Chemically Modified HLA-A2-Restricted T Cell Epitopes. J Immunol., 193, 2014
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4PRE
| Crystal structure of a HLA-B*35:08-HPVG-Q5 | 分子名称: | Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, MHC class I antigen | 著者 | Yu Chih, L, Rossjohn, J, Gras, S. | 登録日 | 2014-03-05 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism. J.Biol.Chem., 289, 2014
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