5DEF

Crystal structure of B*27:04 complex bound to the pVIPR peptide

Summary for 5DEF

• Entry DOI: 10.2210/pdb5def/pdb
• Related: 1OF2 1OGT
• Descriptor: HLA class I histocompatibility antigen, B-27 alpha chain, Beta-2-microglobulin, peptide derived from VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 (pVIPR), ... (6 entities in total)
• Functional Keywords: immune system-complex, immune system, mhc major histocompatibility complex), hla- b*2704
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 45598.98

Authors

Loll, B.,Fabian, H.,Huser, H.,Hee, C.S.,Uchanska-Ziegler, B.,Ziegler, A. (deposition date: 2015-08-25, release date: 2015-11-18, Last modification date: 2024-01-10)

• Primary citation: Loll, B.,Fabian, H.,Huser, H.,Hee, C.S.,Ziegler, A.,Uchanska-Ziegler, B.,Ziegler, A.; Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis.; Arthritis Rheumatol, 68:1172-1182, 2016; PubMed: 26748477; DOI: 10.1002/art.39567

Experimental method

X-RAY DIFFRACTION (1.6 Å)