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PDB: 1179 件

5IRO
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Crystal structure of a complex between the Human adenovirus type 4 E3-19K protein and MHC class molecule HLA-A2/TAX
分子名称: Beta-2-microglobulin, E3 19 kDa protein, HLA class I histocompatibility antigen, ...
著者Li, L, Bouvier, M.
登録日2016-03-14
公開日2016-08-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structure of the Adenovirus Type 4 (Species E) E3-19K/HLA-A2 Complex Reveals Species-Specific Features in MHC Class I Recognition.
J Immunol., 197, 2016
8ES8
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CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Saotome, K, Franklin, M.C.
登録日2022-10-13
公開日2023-05-03
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023
1AKJ
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COMPLEX OF THE HUMAN MHC CLASS I GLYCOPROTEIN HLA-A2 AND THE T CELL CORECEPTOR CD8
分子名称: BETA 2-MICROGLOBULIN, HIV REVERSE TRANSCRIPTASE EPITOPE, MHC CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), ...
著者Tormo, J, Stuart, D.I, Jones, E.Y.
登録日1997-05-21
公開日1997-09-17
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.
Nature, 387, 1997
1QLF
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MHC CLASS I H-2DB COMPLEXED WITH GLYCOPEPTIDE K3G
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, HUMAN BETA-2-MICROGLOBULIN, ...
著者Tormo, J, Jones, E.Y.
登録日1999-08-30
公開日1999-09-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal Structures of Two H-2Db/Glycopeptide Complexes Suggest a Molecular Basis for Ctl Cross-Reactivity
Immunity, 10, 1999
6ZKY
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BU of 6zky by Molmil
Crystal structure of InhA:01 TCR in complex with HLA-E (S147C) bound to InhA (53-61 H3C)
分子名称: Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], HLA class I histocompatibility antigen, ...
著者Srikannathasan, V, Karuppiah, V, Robinson, R.A.
登録日2020-06-30
公開日2022-01-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Eur.J.Immunol., 52, 2022
6Z9X
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BU of 6z9x by Molmil
Human Class I Major Histocompatibility Complex, A02 allele, presenting LLS (t-butyl)Y FGTPT
分子名称: Beta-2-microglobulin, LEU-LEU-SER-TUR-PHE-GLY-THR-PRO-THR, MHC class I antigen, ...
著者Rizkallah, P.J, Man, S, Redman, J.E.
登録日2020-06-04
公開日2021-06-30
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
J Immunol., 207, 2021
4PJA
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Structure of human MR1-5-OP-RU in complex with human MAIT B-B10 TCR
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-05-12
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
5XOV
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Crystal structure of peptide-HLA-A24 bound to S19-2 V-delta/V-beta TCR
分子名称: Beta-2-microglobulin, HIV-1 Nef138-10 peptide, HLA class I histocompatibility antigen, ...
著者Shi, Y, Qi, J, Gao, G.F.
登録日2017-05-31
公開日2017-06-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.684 Å)
主引用文献Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs.
J. Virol., 91, 2017
3PWP
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The complex between TCR A6 and human Class I MHC HLA-A2 with the bound HuD peptide
分子名称: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-12-08
公開日2011-03-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3QDG
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The complex between TCR DMF5 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide
分子名称: Beta-2-microglobulin, DMF5 alpha chain, DMF5 beta chain, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2011-01-18
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
7RYN
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CD1a-sulfatide-gdTCR complex
分子名称: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wegrecki, M, Le Nours, J, Rossjohn, J.
登録日2021-08-25
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors.
Nat Commun, 13, 2022
6SS9
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Human Leukocyte Antigen Class I A02 Carrying LLWNGPMHV
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Rizkallah, P.J, Bovay, A.
登録日2019-09-06
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222by combinatorial peptide library screening.
Mol.Immunol., 125, 2020
1QQD
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BU of 1qqd by Molmil
CRYSTAL STRUCTURE OF HLA-CW4, A LIGAND FOR THE KIR2D NATURAL KILLER CELL INHIBITORY RECEPTOR
分子名称: BETA-2 MICROGLOBULIN, HISTOCOMPATIBILITY LEUKOCYTE ANTIGEN (HLA)-CW4 (HEAVY CHAIN), HLA-CW4 SPECIFIC PEPTIDE
著者Fan, Q.R, Wiley, D.C.
登録日1999-06-03
公開日1999-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of human histocompatibility leukocyte antigen (HLA)-Cw4, a ligand for the KIR2D natural killer cell inhibitory receptor
J.Exp.Med., 190, 1999
7QNG
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BU of 7qng by Molmil
Structure of a MHC I-Tapasin-ERp57 complex
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
著者Mueller, I.K, Thomas, C, Trowitzsch, S, Tampe, R.
登録日2021-12-20
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity.
Nat Commun, 13, 2022
2F74
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Murine MHC class I H-2Db in complex with human b2-microglobulin and LCMV-derived immunodminant peptide gp33
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
著者Achour, A, Michaelsson, J, Harris, R.A, Ljunggren, H.G, Karre, K, Schneider, G, Sandalova, T.
登録日2005-11-30
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis of the Differential Stability and Receptor Specificity of H-2D(b) in Complex with Murine versus Human beta(2)-Microglobulin.
J.Mol.Biol., 356, 2006
6Z9W
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BU of 6z9w by Molmil
Human Class I Major Histocompatibility Complex, A02 allele, presenting LLGWVFAQV
分子名称: Beta-2-microglobulin, LEU-LEU-GLY-TRP-VAL-PHE-ALA-GLN-VAL, MHC class I antigen
著者Rizkallah, P.J, Man, S, Redman, J.E.
登録日2020-06-04
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
J Immunol., 207, 2021
6UK4
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Complex of T cell Receptor with HHAT Neoantigen Peptide KQWLVWLFL Presented by HLA-A206
分子名称: 302 TIL T cell receptor alpha chain, 302 TIL T cell receptor beta chain, Beta-2-microglobulin, ...
著者Devlin, J.R, Baker, B.M.
登録日2019-10-04
公開日2020-08-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Nat.Chem.Biol., 16, 2020
1EXU
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BU of 1exu by Molmil
CRYSTAL STRUCTURE OF THE HUMAN MHC-RELATED FC RECEPTOR
分子名称: BETA-2-MICROGLOBULIN, BETA-MERCAPTOETHANOL, IGG RECEPTOR FCRN LARGE SUBUNIT P51
著者West Jr, A.P, Bjorkman, P.J.
登録日2000-05-04
公開日2000-08-10
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,).
Biochemistry, 39, 2000
8RBU
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Crystal structure of HLA-A*11:01 in complex with SVLNDILARL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ...
著者Ahn, Y.M, Maddumage, J.C, Szeto, C, Gras, S.
登録日2023-12-05
公開日2024-05-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
Curr Res Struct Biol, 7, 2024
1CG9
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COMPLEX RECOGNITION OF THE SUPERTYPIC BW6-DETERMINANT ON HLA-B AND-C MOLECULES BY THE MONOCLONAL ANTIBODY SFR8-B6
分子名称: PROTEIN (BETA-2-MICROGLOBULIN), PROTEIN (EBNA-6 NUCLEAR PROTEIN (EBNA-3C) (EBNA-4B)), PROTEIN (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Menssen, R, Orth, P, Ziegler, A, Saenger, W.
登録日1999-03-25
公開日2003-11-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Complex Recognition of the Supertypic Bw6-Determinant on HLA-B and-C Molecules by the Monoclonal Antibody SFR8-B6
To be Published
4JFE
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Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
登録日2013-02-28
公開日2013-05-29
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
5YXU
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an affinity enhanced T cell receptor in complex with HLA-A0201 restricted HCV NS3 peptide KLVALGINAV
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Yi, L.
登録日2017-12-07
公開日2018-12-12
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献an affinity enhanced T cell receptor in complex with HLA-A0201 restricted HCV NS3 peptide KLVALGINAV
To Be Published
4NO0
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Crystal structure of non-phosphorylated form of RQA_V phosphopeptide bound to HLA-A2 in complex with LILRB1
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Mohammed, F, Stones, D.H, Willcox, B.E.
登録日2013-11-19
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
2NX5
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Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A
分子名称: Beta-2-microglobulin, EBV peptide, EPLPQGQLTAY, ...
著者Tynan, F.E, Reid, H.H, Rossjohn, J.
登録日2006-11-16
公開日2007-02-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Nat.Immunol., 8, 2007
3MZT
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Protein-induced photophysical changes to the amyloid indicator dye, thioflavin T
分子名称: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Beta-2-microglobulin, COPPER (II) ION
著者Wolfe, L.S, Calabrese, M.F, Nath, A, Blaho, D.V, Miranker, A.D, Xiong, Y.
登録日2010-05-13
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Protein-induced photophysical changes to the amyloid indicator dye thioflavin T.
Proc.Natl.Acad.Sci.USA, 107, 2010

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件を2024-08-07に公開中

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