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PDB: 16 件
1WWW
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NGF IN COMPLEX WITH DOMAIN 5 OF THE TRKA RECEPTOR
分子名称: PROTEIN (NERVE GROWTH FACTOR), PROTEIN (TRKA RECEPTOR)
著者Wiesmann, C, Ultsch, M.H, De Vos, A.M.
登録日1999-03-12
公開日1999-09-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.
Nature, 401, 1999
6YW8
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NMR solution structure of unbound recombinant human Nerve Growth Factor (rhNGF)
分子名称: Beta-nerve growth factor
著者Golic Grdadolnik, S, Paoletti, F.
登録日2020-04-29
公開日2021-05-12
最終更新日2024-07-03
実験手法SOLUTION NMR
主引用文献Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions.
Comput Struct Biotechnol J, 19, 2021
5JZ7
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NGF IN COMPLEX WITH MEDI578 scFv
分子名称: Beta-nerve growth factor, MEDI578 scFv, heavy chain, ...
著者Olsson, L.-L, Aagaard, A.
登録日2016-05-16
公開日2017-01-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.
Sci Rep, 6, 2016
4ZBN
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Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-nerve growth factor, DNA (28-MER)
著者Davies, D.R, Edwards, T.E.
登録日2015-04-15
公開日2015-06-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.447 Å)
主引用文献Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.
Structure, 23, 2015
2IFG
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Structure of the extracellular segment of human TRKA in complex with nerve growth factor
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-nerve growth factor, High affinity nerve growth factor receptor, ...
著者He, X, Garcia, K.C.
登録日2006-09-20
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.
Neuron, 53, 2007
1SG1
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Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common Neurotrophin Receptor p75
分子名称: Beta-nerve growth factor, CHLORIDE ION, Tumor necrosis factor receptor superfamily member 16
著者He, X.L, Garcia, K.C.
登録日2004-02-22
公開日2004-06-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of nerve growth factor complexed with the shared neurotrophin receptor p75
Science, 304, 2004
6FFY
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Structure of the mouse SorCS2-NGF complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-nerve growth factor, VPS10 domain-containing receptor SorCS2, ...
著者Leloup, N.O.L, Janssen, B.J.C.
登録日2018-01-09
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural insights into SorCS2-Nerve Growth Factor complex formation.
Nat Commun, 9, 2018
3IJ2
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Ligand-receptor structure
分子名称: Beta-nerve growth factor, Nerve growth factor receptor (TNFR superfamily, member 16)
著者Feng, D, Garcia, K.C.
登録日2009-08-03
公開日2010-01-12
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献Molecular and structural insight into proNGF engagement of p75NTR and sortilin.
J.Mol.Biol., 396, 2010
5LSD
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recombinant mouse Nerve Growth Factor
分子名称: Beta-nerve growth factor
著者Paoletti, F, de Chiara, C, Kelly, G, Lamba, D, Cattaneo, A, Pastore, A.
登録日2016-08-25
公開日2017-07-05
最終更新日2024-07-03
実験手法SOLUTION NMR
主引用文献Conformational Rigidity within Plasticity Promotes Differential Target Recognition of Nerve Growth Factor.
Front Mol Biosci, 3, 2016
4XPJ
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Crystal structure of Nerve growth factor in complex with lysophosphatidylinositol
分子名称: (2R)-2-hydroxy-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl tridecanoate, Beta-nerve growth factor
著者Sun, H.L, Jiang, T.
登録日2015-01-17
公開日2015-07-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.605 Å)
主引用文献The structure of nerve growth factor in complex with lysophosphatidylinositol
Acta Crystallogr.,Sect.F, 71, 2015
1SGF
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CRYSTAL STRUCTURE OF 7S NGF: A COMPLEX OF NERVE GROWTH FACTOR WITH FOUR BINDING PROTEINS (SERINE PROTEINASES)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NERVE GROWTH FACTOR, ...
著者Bax, B.D.V, Blundell, T.L, Murray-Rust, J, Mcdonald, N.Q.
登録日1997-08-08
公開日1998-05-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins.
Structure, 5, 1997
4EDX
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Nerve Growth Factor in Complex with Fab from mouse mAb 911
分子名称: Beta-nerve growth factor, heavy chain of Fab of murine anti-NGF, light chain of FAB of murine anti-NGF
著者Eigenbrot, C, Ultsch, M.
登録日2012-03-27
公開日2014-04-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs, 6
4EDW
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Nerve Growth Factor in Complex with Fab from humanized version of mouse mAb 911 (tanezumab)
分子名称: Beta-nerve growth factor, GLYCEROL, tanezumab Fab heavy chain, ...
著者Eigenbrot, C, Ultsch, M.
登録日2012-03-27
公開日2014-04-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs, 6
4EAX
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Mouse NGF in complex with Lyso-PS
分子名称: Beta-nerve growth factor, O-[(S)-hydroxy{[(2S)-2-hydroxy-3-(octadec-9-enoyloxy)propyl]oxy}phosphoryl]-L-serine
著者Jiang, T, Tong, Q.
登録日2012-03-23
公開日2012-09-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional insights into lipid-bound nerve growth factors
Faseb J., 26, 2012
1BET
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NEW PROTEIN FOLD REVEALED BY A 2.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF NERVE GROWTH FACTOR
分子名称: BETA-NERVE GROWTH FACTOR
著者Mcdonald, N.Q, Lapatto, R, Murray-Rust, J, Gunning, J, Wlodawer, A, Blundell, T.L.
登録日1993-04-08
公開日1994-05-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor.
Nature, 354, 1991
1BTG
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CRYSTAL STRUCTURE OF BETA NERVE GROWTH FACTOR AT 2.5 A RESOLUTION IN C2 SPACE GROUP WITH ZN IONS BOUND
分子名称: BETA NERVE GROWTH FACTOR, ZINC ION
著者Holland, D.R, Matthews, B.W.
登録日1995-08-29
公開日1996-03-08
最終更新日2020-07-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites.
J.Mol.Biol., 239, 1994

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