7JWX
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![BU of 7jwx by Molmil](/molmil-images/mine/7jwx) | Crystal Structure of Trypsin Bound O-methyl Benzamidine | 分子名称: | 4-[(1-{(1S,2S)-1-[1-(4-aminobutyl)-1H-1,2,3-triazol-4-yl]-2-methylbutyl}-1H-1,2,3-triazol-4-yl)methoxy]-3-methoxybenzene-1-carboximidamide, CALCIUM ION, CHLORIDE ION, ... | 著者 | Packianathan, C, Laganowsky, A. | 登録日 | 2020-08-26 | 公開日 | 2021-08-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Small molecule peptidomimetic trypsin inhibitors: validation of an EKO binding mode, but with a twist. Org.Biomol.Chem., 20, 2022
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3UQV
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![BU of 3uqv by Molmil](/molmil-images/mine/3uqv) | Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor | 分子名称: | 3-(3-carbamimidoylphenyl)-N-(2'-sulfamoylbiphenyl-4-yl)-1,2-oxazole-4-carboxamide, CALCIUM ION, Cationic trypsin, ... | 著者 | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | 登録日 | 2011-11-21 | 公開日 | 2012-11-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
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3I29
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![BU of 3i29 by Molmil](/molmil-images/mine/3i29) | Crystal structure of a binary complex between an mutant trypsin inhibitor with bovine trypsin | 分子名称: | CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3 | 著者 | Khamrui, S, Majumder, S, Dasgupta, J, Dattagupta, J.K, Sen, U. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors Biochim.Biophys.Acta, 1824, 2012
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6B6O
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![BU of 6b6o by Molmil](/molmil-images/mine/6b6o) | |
3E8L
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![BU of 3e8l by Molmil](/molmil-images/mine/3e8l) | The Crystal Structure of the Double-headed Arrowhead Protease Inhibitor A in Complex with Two Trypsins | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | 著者 | Bao, R, Jiang, C.-H, Chi, C.W, Lin, S.X, Chen, Y.X. | 登録日 | 2008-08-20 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | The ternary structure of double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation. J.Biol.Chem., 284, 2009
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2F3C
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![BU of 2f3c by Molmil](/molmil-images/mine/2f3c) | Crystal structure of infestin 1, a Kazal-type serineprotease inhibitor, in complex with trypsin | 分子名称: | CALCIUM ION, Cationic trypsin, SULFATE ION, ... | 著者 | Campos, I.T.N, Tanaka, A.S, Barbosa, J.A.R.G. | 登録日 | 2005-11-20 | 公開日 | 2006-12-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Kazal-type inhibitors infestins 1 and 4 differ in specificity but are similar in three-dimensional structure. Acta Crystallogr.,Sect.D, 68, 2012
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1K1L
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![BU of 1k1l by Molmil](/molmil-images/mine/1k1l) | BOVINE TRYPSIN-INHIBITOR COMPLEX | 分子名称: | CALCIUM ION, N-ALPHA-(2-NAPHTHYLSULFONYL)-3-AMIDINO-L-PHENYLALANINE PIPERAZIDE, SULFATE ION, ... | 著者 | Stubbs, M.T. | 登録日 | 2001-09-25 | 公開日 | 2001-11-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313, 2001
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2QYI
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![BU of 2qyi by Molmil](/molmil-images/mine/2qyi) | Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin | 分子名称: | CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3, ... | 著者 | Khamrui, S, Dasgupta, J, Dattagupta, J.K, Sen, U. | 登録日 | 2007-08-15 | 公開日 | 2008-08-19 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin To be Published
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2TLD
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![BU of 2tld by Molmil](/molmil-images/mine/2tld) | CRYSTAL STRUCTURE OF AN ENGINEERED SUBTILISIN INHIBITOR COMPLEXED WITH BOVINE TRYPSIN | 分子名称: | STREPTOMYCES SUBTILISIN INHIBITOR (SSI), TRYPSIN | 著者 | Mitsui, Y, Takeuchi, Y, Nonaka, T, Nakamura, K.T. | 登録日 | 1991-09-16 | 公開日 | 1992-07-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of an engineered subtilisin inhibitor complexed with bovine trypsin. Proc.Natl.Acad.Sci.USA, 89, 1992
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1EZX
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5GIB
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![BU of 5gib by Molmil](/molmil-images/mine/5gib) | Succinic acid bound trypsin crystallized as dimer | 分子名称: | CALCIUM ION, Cationic trypsin, SUCCINIC ACID | 著者 | Kutumbarao, N.H.V, Manohar, R, KarthiK, L, Malathy, P, Gunasekaran, K, Velmurugan, D. | 登録日 | 2016-06-22 | 公開日 | 2016-08-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | 主引用文献 | Trypsin bound with Succinic acid To Be Published
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3T28
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![BU of 3t28 by Molmil](/molmil-images/mine/3t28) | TMAO-grown trypsin (bovine)-previously unreported tetragonal crystal form | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Cahn, J, Venkat, M, Saxby, S, Juers, D. | 登録日 | 2011-07-22 | 公開日 | 2011-12-28 | 最終更新日 | 2018-03-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
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5GXP
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4NIY
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![BU of 4niy by Molmil](/molmil-images/mine/4niy) | Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) complexed to YRH-ecotin (M84Y/M85R/A86H ecotin) | 分子名称: | CALCIUM ION, Cationic trypsin, Ecotin, ... | 著者 | Schoepfel, M, Parthier, C, Stubbs, M.T. | 登録日 | 2013-11-08 | 公開日 | 2014-02-19 | 最終更新日 | 2014-03-19 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | N-terminal protein modification by substrate-activated reverse proteolysis. Angew.Chem.Int.Ed.Engl., 53, 2014
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7AL8
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1QL8
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2QN5
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![BU of 2qn5 by Molmil](/molmil-images/mine/2qn5) | Crystal Structure and Functional Study of the Bowman-Birk Inhibitor from Rice Bran in Complex with Bovine Trypsin | 分子名称: | Bowman-Birk type bran trypsin inhibitor, Cationic trypsin | 著者 | Li, H.T, Lin, Y.H, Guan, H.H, Hsieh, Y.C, Wang, A.H.J, Chen, C.J. | 登録日 | 2007-07-18 | 公開日 | 2008-07-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure and Functional Study of the Bowman-Birk Inhibitor from Rice Bran in Complex with Bovine Trypsin To be Published
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3UY9
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![BU of 3uy9 by Molmil](/molmil-images/mine/3uy9) | Bovine trypsin variant X(tripleGlu217Phe227) in complex with small molecule inhibitor | 分子名称: | BENZAMIDINE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | 登録日 | 2011-12-06 | 公開日 | 2012-12-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
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1C9T
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![BU of 1c9t by Molmil](/molmil-images/mine/1c9t) | COMPLEX OF BDELLASTASIN WITH BOVINE TRYPSIN | 分子名称: | BDELLASTASIN, TRYPSIN | 著者 | Rester, U, Bode, W, Moser, M, Parry, M.A, Huber, R, Auerswald, E. | 登録日 | 1999-08-03 | 公開日 | 2000-08-03 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system. J.Mol.Biol., 293, 1999
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6DWU
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![BU of 6dwu by Molmil](/molmil-images/mine/6dwu) | |