7JWX
 
 | | Crystal Structure of Trypsin Bound O-methyl Benzamidine | | 分子名称: | 4-[(1-{(1S,2S)-1-[1-(4-aminobutyl)-1H-1,2,3-triazol-4-yl]-2-methylbutyl}-1H-1,2,3-triazol-4-yl)methoxy]-3-methoxybenzene-1-carboximidamide, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Packianathan, C, Laganowsky, A. | | 登録日 | 2020-08-26 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Small molecule peptidomimetic trypsin inhibitors: validation of an EKO binding mode, but with a twist.
Org.Biomol.Chem., 20, 2022
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3UQV
 | | Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor | | 分子名称: | 3-(3-carbamimidoylphenyl)-N-(2'-sulfamoylbiphenyl-4-yl)-1,2-oxazole-4-carboxamide, CALCIUM ION, Cationic trypsin, ... | | 著者 | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | | 登録日 | 2011-11-21 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues.
Biol.Chem., 395, 2014
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3I29
 | | Crystal structure of a binary complex between an mutant trypsin inhibitor with bovine trypsin | | 分子名称: | CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3 | | 著者 | Khamrui, S, Majumder, S, Dasgupta, J, Dattagupta, J.K, Sen, U. | | 登録日 | 2009-06-29 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors
Biochim.Biophys.Acta, 1824, 2012
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6B6O
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3E8L
 | | The Crystal Structure of the Double-headed Arrowhead Protease Inhibitor A in Complex with Two Trypsins | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | 著者 | Bao, R, Jiang, C.-H, Chi, C.W, Lin, S.X, Chen, Y.X. | | 登録日 | 2008-08-20 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | The ternary structure of double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation.
J.Biol.Chem., 284, 2009
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2F3C
 | | Crystal structure of infestin 1, a Kazal-type serineprotease inhibitor, in complex with trypsin | | 分子名称: | CALCIUM ION, Cationic trypsin, SULFATE ION, ... | | 著者 | Campos, I.T.N, Tanaka, A.S, Barbosa, J.A.R.G. | | 登録日 | 2005-11-20 | | 公開日 | 2006-12-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Kazal-type inhibitors infestins 1 and 4 differ in specificity but are similar in three-dimensional structure.
Acta Crystallogr.,Sect.D, 68, 2012
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1K1L
 | | BOVINE TRYPSIN-INHIBITOR COMPLEX | | 分子名称: | CALCIUM ION, N-ALPHA-(2-NAPHTHYLSULFONYL)-3-AMIDINO-L-PHENYLALANINE PIPERAZIDE, SULFATE ION, ... | | 著者 | Stubbs, M.T. | | 登録日 | 2001-09-25 | | 公開日 | 2001-11-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition.
J.Mol.Biol., 313, 2001
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2QYI
 | | Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin | | 分子名称: | CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3, ... | | 著者 | Khamrui, S, Dasgupta, J, Dattagupta, J.K, Sen, U. | | 登録日 | 2007-08-15 | | 公開日 | 2008-08-19 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin
To be Published
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2TLD
 | | CRYSTAL STRUCTURE OF AN ENGINEERED SUBTILISIN INHIBITOR COMPLEXED WITH BOVINE TRYPSIN | | 分子名称: | STREPTOMYCES SUBTILISIN INHIBITOR (SSI), TRYPSIN | | 著者 | Mitsui, Y, Takeuchi, Y, Nonaka, T, Nakamura, K.T. | | 登録日 | 1991-09-16 | | 公開日 | 1992-07-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of an engineered subtilisin inhibitor complexed with bovine trypsin.
Proc.Natl.Acad.Sci.USA, 89, 1992
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1EZX
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5GIB
 | | Succinic acid bound trypsin crystallized as dimer | | 分子名称: | CALCIUM ION, Cationic trypsin, SUCCINIC ACID | | 著者 | Kutumbarao, N.H.V, Manohar, R, KarthiK, L, Malathy, P, Gunasekaran, K, Velmurugan, D. | | 登録日 | 2016-06-22 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | | 主引用文献 | Trypsin bound with Succinic acid
To Be Published
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3T28
 | | TMAO-grown trypsin (bovine)-previously unreported tetragonal crystal form | | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | | 著者 | Cahn, J, Venkat, M, Saxby, S, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2018-03-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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5GXP
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4NIY
 | | Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) complexed to YRH-ecotin (M84Y/M85R/A86H ecotin) | | 分子名称: | CALCIUM ION, Cationic trypsin, Ecotin, ... | | 著者 | Schoepfel, M, Parthier, C, Stubbs, M.T. | | 登録日 | 2013-11-08 | | 公開日 | 2014-02-19 | | 最終更新日 | 2014-03-19 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | N-terminal protein modification by substrate-activated reverse proteolysis.
Angew.Chem.Int.Ed.Engl., 53, 2014
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7AL8
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1QL8
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2QN5
 | | Crystal Structure and Functional Study of the Bowman-Birk Inhibitor from Rice Bran in Complex with Bovine Trypsin | | 分子名称: | Bowman-Birk type bran trypsin inhibitor, Cationic trypsin | | 著者 | Li, H.T, Lin, Y.H, Guan, H.H, Hsieh, Y.C, Wang, A.H.J, Chen, C.J. | | 登録日 | 2007-07-18 | | 公開日 | 2008-07-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal Structure and Functional Study of the Bowman-Birk Inhibitor from Rice Bran in Complex with Bovine Trypsin
To be Published
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3UY9
 | | Bovine trypsin variant X(tripleGlu217Phe227) in complex with small molecule inhibitor | | 分子名称: | BENZAMIDINE, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | | 登録日 | 2011-12-06 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues.
Biol.Chem., 395, 2014
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1C9T
 | | COMPLEX OF BDELLASTASIN WITH BOVINE TRYPSIN | | 分子名称: | BDELLASTASIN, TRYPSIN | | 著者 | Rester, U, Bode, W, Moser, M, Parry, M.A, Huber, R, Auerswald, E. | | 登録日 | 1999-08-03 | | 公開日 | 2000-08-03 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system.
J.Mol.Biol., 293, 1999
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6DWU
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