3I29

Crystal structure of a binary complex between an mutant trypsin inhibitor with bovine trypsin

Summary for 3I29

Entry DOI	10.2210/pdb3i29/pdb
Related	2QYI 3I2A 3I2X
Descriptor	Cationic trypsin, Chymotrypsin inhibitor 3, CALCIUM ION, ... (4 entities in total)
Functional Keywords	p1 and p2 mutant, trypsin inhibitor, bovine trypsin, complex, digestion, hydrolase, metal-binding, protease, secreted, serine protease, zymogen, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, disulfide bond, hydrolase/hydrolase inhibitor
Biological source	Bos taurus (bovine) More
Cellular location	Secreted, extracellular space: P00760
Total number of polymer chains	2
Total formula weight	44104.72
Authors	Khamrui, S.,Majumder, S.,Dasgupta, J.,Dattagupta, J.K.,Sen, U. (deposition date: 2009-06-29, release date: 2010-06-16, Last modification date: 2023-11-01)
Primary citation	Majumder, S.,Khamrui, S.,Dasgupta, J.,Dattagupta, J.K.,Sen, U. Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors Biochim.Biophys.Acta, 1824:882-890, 2012 Cited by PubMed: 22709512 DOI: 10.1016/j.bbapap.2012.04.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation