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PDB: 31 件
3IVV
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BU of 3ivv by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-PucSBC1_pep1
分子名称: PucSBC1, Speckle-type POZ protein
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-09-01
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3HSV
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BU of 3hsv by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2
分子名称: Core histone macro-H2A.1, SULFATE ION, Speckle-type POZ protein, ...
著者Zhuang, M, Schulman, B.A, Miller, D.
登録日2009-06-10
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
7LIN
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BU of 7lin by Molmil
X-ray structure of SPOP MATH domain (D140G) in complex with a 53BP1 peptide
分子名称: SULFATE ION, Speckle-type POZ protein, TP53-binding protein 1 peptide
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7D3D
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BU of 7d3d by Molmil
Crystal structure of SPOP bound with a peptide
分子名称: GLU-VAL-SER-ILE-ILE-GLN-GLY-ALA-ASP-SER-THR-THR, GLYCEROL, Speckle-type POZ protein
著者Yang, C.-G, Gan, J.H.
登録日2020-09-18
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A peptide binder of E3 ligase adaptor SPOP disrupts oncogenic SPOP-protein interactions in kidney cancer cells.
Chin.J.Chem., 39, 2021
7LIP
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BU of 7lip by Molmil
X-ray structure of SPOP MATH domain (D140G)
分子名称: SULFATE ION, Speckle-type POZ protein
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
4HS2
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BU of 4hs2 by Molmil
Crystal Structure of the Human SPOP C-terminal Domain
分子名称: Speckle-type POZ protein
著者Van Geersdaele, L.K, Stead, M.A, Carr, S.B, Wright, S.C.
登録日2012-10-29
公開日2013-09-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP.
Acta Crystallogr.,Sect.D, 69, 2013
3HQL
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BU of 3hql by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases:SPOPMATHx-PucSBC1_pep2
分子名称: Puckered, SULFATE ION, Speckle-type POZ protein
著者Zhuang, M, Schulman, B.A.
登録日2009-06-07
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HQM
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BU of 3hqm by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-CiSBC2
分子名称: Protein cubitus interruptus, SULFATE ION, Speckle-type POZ protein
著者Zhuang, M, Schulman, B.A.
登録日2009-06-07
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3IVB
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BU of 3ivb by Molmil
Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1
分子名称: CHLORIDE ION, Core histone macro-H2A.1, Speckle-type POZ protein, ...
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-08-31
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure 9
To be Published
6I5P
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BU of 6i5p by Molmil
Co-crystal structure of human SPOP MATH domain (E47K) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-14
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I68
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BU of 6i68 by Molmil
Co-crystal structure of human SPOP MATH domain (M117V) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-15
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I41
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BU of 6i41 by Molmil
Co-crystal structure of human SPOP MATH domain (wild-type) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-08
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
7LIQ
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BU of 7liq by Molmil
X-ray structure of SPOP MATH domain (S119A)
分子名称: Speckle-type POZ protein
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
4O1V
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BU of 4o1v by Molmil
SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer
分子名称: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Speckle-type POZ protein
著者Calabrese, M.F, Watson, E.R, Schulman, B.A.
登録日2013-12-16
公開日2014-04-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer.
Cancer Cell, 25, 2014
6F8F
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BU of 6f8f by Molmil
Co-crystal structure of SPOP MATH domain and human Pdx1 fragment
分子名称: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2017-12-13
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
6F8G
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BU of 6f8g by Molmil
Co-crystal structure of SPOP MATH domain and hamster Pdx1 fragment
分子名称: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2017-12-13
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
3IVQ
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BU of 3ivq by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-CiSBC2
分子名称: CiSBC2, Speckle-type POZ protein
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-09-01
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
6I7A
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BU of 6i7a by Molmil
Co-crystal structure of human SPOP MATH domain (D140N) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-16
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
3HQH
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BU of 3hqh by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep1
分子名称: MacroH2A, Speckle-type POZ protein, ZINC ION
著者Zhuang, M, Schulman, B.A.
登録日2009-06-06
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
4EOZ
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BU of 4eoz by Molmil
Crystal structure of the SPOP BTB domain complexed with the Cul3 N-terminal domain
分子名称: Cullin-3, Speckle-type POZ protein
著者Prive, G.G, Errington, W.J.
登録日2012-04-16
公開日2012-05-30
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase.
Structure, 20, 2012
4J8Z
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BU of 4j8z by Molmil
Crystal Structure of the Human SPOP BTB Domain
分子名称: Speckle-type POZ protein
著者Stead, M.A, Wright, S.C.
登録日2013-02-15
公開日2013-09-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP
Acta Crystallogr.,Sect.D, 69, 2013
3HTM
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BU of 3htm by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPBTB/3-box
分子名称: Speckle-type POZ protein
著者Zhuang, M, Walden, H, Schulman, B.A.
登録日2009-06-11
公開日2009-10-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HQI
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BU of 3hqi by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1
分子名称: PucSBC1, Speckle-type POZ protein
著者Zhuang, M, Schulman, B.A.
登録日2009-06-07
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HU6
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BU of 3hu6 by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1
分子名称: Puckered, Speckle-type POZ protein
著者Zhuang, M, Schulman, B.A.
登録日2009-06-13
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
7LIO
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BU of 7lio by Molmil
X-ray structure of SPOP MATH domain (S119D) in complex with a 53BP1 peptide
分子名称: Speckle-type POZ protein, TP53-binding protein 1 peptide
著者Botuyan, M.V, Cui, G, Mer, G.
登録日2021-01-27
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021

 

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