Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPBTB/3-box

Summary for 3HTM

Related3HQI 3HQL 3HQM 3HSV 3HU6 3HVE
DescriptorSpeckle-type POZ protein (2 entities in total)
Functional Keywordsbtb, spop, ubiquitin, ligase, nucleus, ubl conjugation pathway, protein binding
Biological sourceHomo sapiens (human)
Cellular locationNucleus O43791
Total number of polymer chains4
Total molecular weight77182.5
Zhuang, M.,Walden, H.,Schulman, B.A. (deposition date: 2009-06-11, release date: 2009-10-20, Last modification date: 2011-07-13)
Primary citation
Zhuang, M.,Calabrese, M.F.,Liu, J.,Waddell, M.B.,Nourse, A.,Hammel, M.,Miller, D.J.,Walden, H.,Duda, D.M.,Seyedin, S.N.,Hoggard, T.,Harper, J.W.,White, K.P.,Schulman, B.A.
Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36:39-50, 2009
PubMed: 19818708 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2009.09.022
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2271501.6%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution