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PDB: 15 件

1ZIW
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Human Toll-like Receptor 3 extracellular domain structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Wilson, I.A, Choe, J.
登録日2005-04-27
公開日2005-06-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human toll-like receptor 3 (TLR3) ectodomain.
Science, 309, 2005
7WV3
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Toll-like receptor3 linear cluster
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (80-MER), ...
著者Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O.
登録日2022-02-09
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
2A0Z
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The molecular structure of toll-like receptor 3 ligand binding domain
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Bell, J.K, Botos, I, Hall, P.R, Askins, J, Shiloach, J, Segal, D.M, Davies, D.R.
登録日2005-06-17
公開日2005-08-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The molecular structure of the Toll-like receptor 3 ligand-binding domain
Proc.Natl.Acad.Sci.USA, 102, 2005
7WV5
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ectoTLR3-poly(I:C)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (46-MER), ...
著者Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O.
登録日2022-02-09
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
7WVE
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CT-mut (D523K,D524K,E527K) TLR3-poly(I:C) complex
分子名称: RNA (46-MER), Toll-like receptor 3
著者Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O.
登録日2022-02-10
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
7WVJ
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NT-mut(K117D,K139D,K145D) TLR3 -poly I:C complex
分子名称: RNA (46-MER), Toll-like receptor 3
著者Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O.
登録日2022-02-10
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
5GS0
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Crystal structure of the complex of TLR3 and bi-specific diabody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 3, alpha-D-mannopyranose, ...
著者Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O.
登録日2016-08-13
公開日2016-10-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.275 Å)
主引用文献Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.
Sci Rep, 6, 2016
7WV4
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ectoTLR3-poly(I:C) cluster
分子名称: RNA (80-MER), Toll-like receptor 3
著者Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O.
登録日2022-02-09
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
7C76
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Cryo-EM structure of human TLR3 in complex with UNC93B1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein unc-93 homolog B1, ...
著者Ohto, U, Ishida, H, Shimizu, T.
登録日2020-05-23
公開日2021-01-06
最終更新日2021-02-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of Toll-like receptors in complex with UNC93B1.
Nat.Struct.Mol.Biol., 28, 2021
3ULU
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BU of 3ulu by Molmil
Structure of quaternary complex of human TLR3ecd with three Fabs (Form1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ...
著者Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A.
登録日2011-11-11
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
3ULV
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Structure of quaternary complex of human TLR3ecd with three Fabs (Form2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ...
著者Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A.
登録日2011-11-11
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.522 Å)
主引用文献Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
7WVF
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ectoTLR3-mAb12-poly(I:C) complex
分子名称: RNA (46-MER), Toll-like receptor 3, mAb12
著者Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O.
登録日2022-02-10
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
2MK9
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BU of 2mk9 by Molmil
Spatial structure of the dimeric transmembrane domain of Toll-like receptor 3
分子名称: Toll-like receptor 3
著者Mineev, K.S, Goncharuk, S.A, Arseniev, A.S.
登録日2014-02-04
公開日2014-09-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Toll-like receptor 3 transmembrane domain is able to perform various homotypic interactions: An NMR structural study.
Febs Lett., 588, 2014
2MKA
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Spatial structure of the Toll-like receptor 3 transmembrane domain in the trimeric state
分子名称: Toll-like receptor 3
著者Mineev, K, Gonscharuk, S.A, Arseniev, A.S.
登録日2014-02-04
公開日2014-09-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Toll-like receptor 3 transmembrane domain is able to perform various homotypic interactions: An NMR structural study.
Febs Lett., 588, 2014
8AR1
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Solution structure of TLR3 transmembrane and cytoplasmic juxtamembrane regions
分子名称: Toll-like receptor 3
著者Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S.
登録日2022-08-15
公開日2023-03-22
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023

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件を2024-07-17に公開中

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