1ZIW
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![BU of 1ziw by Molmil](/molmil-images/mine/1ziw) | Human Toll-like Receptor 3 extracellular domain structure | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | 著者 | Wilson, I.A, Choe, J. | 登録日 | 2005-04-27 | 公開日 | 2005-06-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of human toll-like receptor 3 (TLR3) ectodomain. Science, 309, 2005
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7WV3
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![BU of 7wv3 by Molmil](/molmil-images/mine/7wv3) | Toll-like receptor3 linear cluster | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (80-MER), ... | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-09 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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2A0Z
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![BU of 2a0z by Molmil](/molmil-images/mine/2a0z) | The molecular structure of toll-like receptor 3 ligand binding domain | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Bell, J.K, Botos, I, Hall, P.R, Askins, J, Shiloach, J, Segal, D.M, Davies, D.R. | 登録日 | 2005-06-17 | 公開日 | 2005-08-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The molecular structure of the Toll-like receptor 3 ligand-binding domain Proc.Natl.Acad.Sci.USA, 102, 2005
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7WV5
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![BU of 7wv5 by Molmil](/molmil-images/mine/7wv5) | ectoTLR3-poly(I:C) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (46-MER), ... | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-09 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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7WVE
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![BU of 7wve by Molmil](/molmil-images/mine/7wve) | CT-mut (D523K,D524K,E527K) TLR3-poly(I:C) complex | 分子名称: | RNA (46-MER), Toll-like receptor 3 | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-10 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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7WVJ
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![BU of 7wvj by Molmil](/molmil-images/mine/7wvj) | NT-mut(K117D,K139D,K145D) TLR3 -poly I:C complex | 分子名称: | RNA (46-MER), Toll-like receptor 3 | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-10 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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5GS0
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![BU of 5gs0 by Molmil](/molmil-images/mine/5gs0) | Crystal structure of the complex of TLR3 and bi-specific diabody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 3, alpha-D-mannopyranose, ... | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | 登録日 | 2016-08-13 | 公開日 | 2016-10-12 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.275 Å) | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 2016
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7WV4
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![BU of 7wv4 by Molmil](/molmil-images/mine/7wv4) | ectoTLR3-poly(I:C) cluster | 分子名称: | RNA (80-MER), Toll-like receptor 3 | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-09 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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7C76
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![BU of 7c76 by Molmil](/molmil-images/mine/7c76) | Cryo-EM structure of human TLR3 in complex with UNC93B1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein unc-93 homolog B1, ... | 著者 | Ohto, U, Ishida, H, Shimizu, T. | 登録日 | 2020-05-23 | 公開日 | 2021-01-06 | 最終更新日 | 2021-02-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of Toll-like receptors in complex with UNC93B1. Nat.Struct.Mol.Biol., 28, 2021
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3ULU
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![BU of 3ulu by Molmil](/molmil-images/mine/3ulu) | Structure of quaternary complex of human TLR3ecd with three Fabs (Form1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ... | 著者 | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | 登録日 | 2011-11-11 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | 主引用文献 | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421, 2012
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3ULV
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![BU of 3ulv by Molmil](/molmil-images/mine/3ulv) | Structure of quaternary complex of human TLR3ecd with three Fabs (Form2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ... | 著者 | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | 登録日 | 2011-11-11 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.522 Å) | 主引用文献 | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421, 2012
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7WVF
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![BU of 7wvf by Molmil](/molmil-images/mine/7wvf) | ectoTLR3-mAb12-poly(I:C) complex | 分子名称: | RNA (46-MER), Toll-like receptor 3, mAb12 | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-10 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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2MK9
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![BU of 2mk9 by Molmil](/molmil-images/mine/2mk9) | |
2MKA
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![BU of 2mka by Molmil](/molmil-images/mine/2mka) | |
8AR1
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![BU of 8ar1 by Molmil](/molmil-images/mine/8ar1) | Solution structure of TLR3 transmembrane and cytoplasmic juxtamembrane regions | 分子名称: | Toll-like receptor 3 | 著者 | Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S. | 登録日 | 2022-08-15 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors. Nat Commun, 14, 2023
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