5MDZ
 
 | | Structure of the 70S ribosome (empty A site) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2016-11-13 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Translational termination without a stop codon.
Science, 354, 2016
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7PJV
 | | Structure of the 70S-EF-G-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G-GDP-Pi) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | | 登録日 | 2021-08-24 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural mechanism of GTPase-powered ribosome-tRNA movement.
Nat Commun, 12, 2021
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8G7Q
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8G7S
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7PJY
 | | Structure of the 70S-EF-G-GDP ribosome complex with tRNAs in chimeric state 1 (CHI1-EF-G-GDP) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | | 登録日 | 2021-08-24 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural mechanism of GTPase-powered ribosome-tRNA movement.
Nat Commun, 12, 2021
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5J8A
 | | Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | | 著者 | Cocozaki, A, Ferguson, A. | | 登録日 | 2016-04-07 | | 公開日 | 2016-07-06 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6X7K
 | | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | | 登録日 | 2020-05-30 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-09-23 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of transcription-translation coupling.
Science, 369, 2020
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6ENU
 | | Polyproline-stalled ribosome in the presence of elongation-factor P (EF-P) | | 分子名称: | 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Huter, P, Arenz, S, Wilson, D.N. | | 登録日 | 2017-10-06 | | 公開日 | 2017-11-22 | | 最終更新日 | 2018-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
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7NBU
 | | Structure of the HigB1 toxin mutant K95A from Mycobacterium tuberculosis (Rv1955) and its target, the cspA mRNA, on the E. coli Ribosome. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Giudice, E, Mansour, M, Chat, S, D'Urso, G, Gillet, R, Genevaux, P. | | 登録日 | 2021-01-27 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Substrate recognition and cryo-EM structure of the ribosome-bound TAC toxin of Mycobacterium tuberculosis.
Nat Commun, 13, 2022
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5IT8
 | | High-resolution structure of the Escherichia coli ribosome | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | | 著者 | Cocozaki, A, Ferguson, A. | | 登録日 | 2016-03-16 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4V6C
 | | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Zhang, W, Dunkle, J.A, Cate, J.H.D. | | 登録日 | 2009-06-27 | | 公開日 | 2014-07-09 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
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4V7T
 | | Crystal structure of the E. coli ribosome bound to chloramphenicol. | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. | | 登録日 | 2010-08-14 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.1942 Å) | | 主引用文献 | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
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8UQL
 | | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in loaded state, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | | 登録日 | 2023-10-24 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
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6X6T
 | | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B1 (TTC-B1) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | | 登録日 | 2020-05-29 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-09-23 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of transcription-translation coupling.
Science, 369, 2020
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8FZF
 | | Cryo-EM structure of an E. coli rotated ribosome complex bound with RF3-ppGpp and p/E-tRNAPhe (Composite state I-C) | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | | 登録日 | 2023-01-28 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP
Nat.Struct.Mol.Biol., 2024
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6ENF
 | | Cryo-EM structure of a polyproline-stalled ribosome in the absence of EF-P | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Huter, P, Arenz, S, Wilson, D.N. | | 登録日 | 2017-10-04 | | 公開日 | 2017-11-22 | | 最終更新日 | 2018-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
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4V85
 | | Crystal Structure of Release Factor RF3 Trapped in the GTP State on a Rotated Conformation of the Ribosome. | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Zhou, J, Lancaster, L, Trakhanov, S, Noller, H.F. | | 登録日 | 2011-06-13 | | 公開日 | 2014-07-09 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of release factor RF3 trapped in the GTP state on a rotated conformation of the ribosome.
Rna, 18, 2012
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7OIG
 | | CspA-27 cotranslational folding intermediate 3 | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. | | 登録日 | 2021-05-11 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
Embo J., 41, 2022
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6YST
 | | Structure of the P+9 ArfB-ribosome complex with P/E hybrid tRNA in the post-hydrolysis state | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. | | 登録日 | 2020-04-23 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
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7LV0
 | | Pre-translocation rotated ribosome +1-frameshifting(CCC-A) complex (Structure Irot-FS) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A. | | 登録日 | 2021-02-23 | | 公開日 | 2021-07-28 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
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5U9G
 | | 3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure I) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Demo, G, Svidritskiy, E, Madireddy, R, Diaz-Avalos, R, Grant, T, Grigorieff, N, Sousa, D, Korostelev, A.A. | | 登録日 | 2016-12-16 | | 公開日 | 2017-03-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of ribosome rescue by ArfA and RF2.
Elife, 6, 2017
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7K53
 | | Pre-translocation +1-frameshifting(CCC-A) complex (Structure I-FS) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A. | | 登録日 | 2020-09-16 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
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7SSN
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7ST7
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6WNW
 | | Active 70S ribosome without free 5S rRNA and bound with A- and P- tRNA | | 分子名称: | 16S ribosomal RNA, 23s-5s joint ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Loveland, A.B, Korostelev, A.A, Mankin, A.S, Huang, S, Aleksashin, N.A, Klepacki, D, Reier, K, Kefi, A, Szal, A, Remme, J, Jaeger, L, Vazquez-Laslop, N. | | 登録日 | 2020-04-23 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly.
Nat Commun, 11, 2020
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