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PDB: 22 件

7MGM
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BU of 7mgm by Molmil
Structure of yeast cytoplasmic dynein with AAA3 Walker B mutation bound to Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Lahiri, I, Reimer, J.M, Leschziner, A.E.
登録日2021-04-12
公開日2022-01-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for cytoplasmic dynein-1 regulation by Lis1.
Elife, 11, 2022
4AKG
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BU of 4akg by Molmil
Dynein Motor Domain - ATP complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, ...
著者Schmidt, H, Gleave, E.S, Carter, A.P.
登録日2012-02-22
公開日2012-03-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure
Nat.Struct.Mol.Biol., 19, 2012
4AI6
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BU of 4ai6 by Molmil
Dynein Motor Domain - ADP complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, ...
著者Schmidt, H, Gleave, E.S, Carter, A.P.
登録日2012-02-08
公開日2012-03-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure
Nat.Struct.Mol.Biol., 19, 2012
7MI3
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BU of 7mi3 by Molmil
Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 4
分子名称: (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ...
著者Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
登録日2021-04-16
公開日2021-05-26
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
4W8F
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BU of 4w8f by Molmil
Crystal structure of the dynein motor domain in the AMPPNP-bound state
分子名称: Dynein heavy chain lysozyme chimera, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Cheng, H.-C, Bhabha, G, Zhang, N, Vale, R.D.
登録日2014-08-24
公開日2014-11-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.541 Å)
主引用文献Allosteric communication in the Dynein motor domain.
Cell, 159, 2014
8E00
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BU of 8e00 by Molmil
Symmetry expansion of yeast cytoplasmic dynein-1 bound to Lis1 in the chi conformation.
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Reimer, J.M, Lahiri, I, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Nat.Struct.Mol.Biol., 30, 2023
4AKH
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BU of 4akh by Molmil
Dynein Motor Domain - AMPPNP complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, DYNEIN HEAVY CHAIN CYTOPLASMIC, ...
著者Schmidt, H, Gleave, E.S, Carter, A.P.
登録日2012-02-22
公開日2012-03-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure
Nat.Struct.Mol.Biol., 19, 2012
6KIQ
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BU of 6kiq by Molmil
Complex of yeast cytoplasmic dynein MTBD-High and MT with DTT
分子名称: Alpha tubulin, Dynein heavy chain, cytoplasmic, ...
著者Komori, Y, Nishida, N, Shimada, I, Kikkawa, M.
登録日2019-07-19
公開日2020-03-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
7MI8
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BU of 7mi8 by Molmil
Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5
分子名称: Fusion protein of Dynein and Endolysin
著者Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
登録日2021-04-16
公開日2021-05-26
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
4AKI
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BU of 4aki by Molmil
Dynein Motor Domain - LuAc derivative
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, DYNEIN HEAVY CHAIN CYTOPLASMIC, ...
著者Schmidt, H, Gleave, E.S, Carter, A.P.
登録日2012-02-22
公開日2012-03-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure
Nat.Struct.Mol.Biol., 19, 2012
7MI6
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BU of 7mi6 by Molmil
Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound, Model 1
分子名称: (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ...
著者Santarossa, C.C, Urnavicius, L, Coudray, N, Ekeirt, D.C, Bhabha, G, Kapoor, T.M.
登録日2021-04-16
公開日2021-05-26
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
6KIO
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BU of 6kio by Molmil
Complex of yeast cytoplasmic dynein MTBD-High and MT without DTT
分子名称: Dynein heavy chain, cytoplasmic, Tubulin alpha-1A chain, ...
著者Komori, Y, Nishida, N, Shimada, I, Kikkawa, M.
登録日2019-07-19
公開日2020-03-04
最終更新日2020-03-11
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
8DZZ
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BU of 8dzz by Molmil
Cryo-EM structure of chi dynein bound to Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Reimer, J.M, Lahiri, I, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Nat.Struct.Mol.Biol., 30, 2023
7MI1
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BU of 7mi1 by Molmil
X-ray structure of yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound (compound 20)
分子名称: Chimera protein of Dynein and Endolysin
著者Santarossa, C.C, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
登録日2021-04-16
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
5AFR
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BU of 5afr by Molmil
N-terminal fragment of dynein heavy chain
分子名称: DYNEIN HEAVY CHAIN, CYTOPLASMIC
著者Urnavicius, L, Zhang, K, Diamant, A.G, Motz, C, Schlager, M.A, Yu, M, Patel, N.A, Robinson, C.V, Carter, A.P.
登録日2015-01-23
公開日2015-02-18
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献The Structure of the Dynactin Complex and its Interaction with Dynein.
Science, 347, 2015
3QMZ
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BU of 3qmz by Molmil
Crystal structure of the cytoplasmic dynein heavy chain motor domain
分子名称: Cytoplasmic dynein heavy chain, Glutathione-S-transferase
著者Cho, C, Carter, A.P, Jin, L, Vale, R.D.
登録日2011-02-07
公開日2011-03-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Crystal structure of the dynein motor domain.
Science, 331, 2011
5VH9
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BU of 5vh9 by Molmil
Cryo-EM structure of yeast cytoplasmic dynein-1 with Lis1 and ATP
分子名称: Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1
著者Cianfrocco, M.A, DeSantis, M.E, Htet, Z.M, Tran, P.T, Reck-Peterson, S.L, Leschziner, A.E.
登録日2017-04-12
公開日2017-09-06
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein.
Cell, 170, 2017
5VLJ
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BU of 5vlj by Molmil
Cryo-EM structure of yeast cytoplasmic dynein with Walker B mutation at AAA3 in presence of ATP-VO4
分子名称: Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1
著者Cianfrocco, M.A, DeSantis, M.E, Htet, Z.M, Tran, P.T, Reck-Peterson, S.L, Leschziner, A.E.
登録日2017-04-25
公開日2017-09-06
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (10.5 Å)
主引用文献Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein.
Cell, 170, 2017
3J68
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BU of 3j68 by Molmil
Structural mechanism of the dynein powerstroke (pre-powerstroke state)
分子名称: Dynein motor domain
著者Lin, J, Okada, K, Raytchev, M, Smith, M.C, Nicastro, D.
登録日2013-12-23
公開日2014-04-23
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (30 Å)
主引用文献Structural mechanism of the dynein power stroke.
Nat.Cell Biol., 16, 2014
3J67
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BU of 3j67 by Molmil
Structural mechanism of the dynein powerstroke (post-powerstroke state)
分子名称: Dynein motor domain
著者Lin, J, Okada, K, Raytchev, M, Smith, M.C, Nicastro, D.
登録日2013-12-22
公開日2014-04-23
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (34 Å)
主引用文献Structural mechanism of the dynein power stroke.
Nat.Cell Biol., 16, 2014
6KJO
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BU of 6kjo by Molmil
The microtubule-binding domains of yeast cytoplasmic dynein in the low affinity state
分子名称: Dynein heavy chain, cytoplasmic
著者Nishida, N, Komori, Y, Takarada, O, Watanabe, A, Tamura, S, Kubo, S, Shimada, I, Kikkawa, M.
登録日2019-07-22
公開日2020-03-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
6KJN
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BU of 6kjn by Molmil
The microtubule-binding domains of yeast cytoplasmic dynein in the high affinity state
分子名称: Dynein heavy chain, cytoplasmic
著者Nishida, N, Komori, Y, Takarada, O, Watanabe, A, Tamura, S, Kubo, S, Shimada, I, Kikkawa, M.
登録日2019-07-22
公開日2020-03-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020

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