7MI1
X-ray structure of yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound (compound 20)
Summary for 7MI1
| Entry DOI | 10.2210/pdb7mi1/pdb |
| Descriptor | Chimera protein of Dynein and Endolysin (1 entity in total) |
| Functional Keywords | aaa atpase, atpase inhibitor, motor protein |
| Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
| Total number of polymer chains | 1 |
| Total formula weight | 304889.88 |
| Authors | Santarossa, C.C.,Ekiert, D.C.,Bhabha, G.,Kapoor, T.M. (deposition date: 2021-04-16, release date: 2021-05-26, Last modification date: 2023-10-18) |
| Primary citation | Santarossa, C.C.,Mickolajczyk, K.J.,Steinman, J.B.,Urnavicius, L.,Chen, N.,Hirata, Y.,Fukase, Y.,Coudray, N.,Ekiert, D.C.,Bhabha, G.,Kapoor, T.M. Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28:1460-1473.e15, 2021 Cited by PubMed: 34015309DOI: 10.1016/j.chembiol.2021.04.024 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.5 Å) |
Structure validation
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