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7MI1

X-ray structure of yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound (compound 20)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Chimera protein of Dynein and Endolysinpolymer2661304889.91UniProt (P36022)
UniProt (D9IEF7)
Pfam (PF08393)
Pfam (PF03028)
Pfam (PF18198)
Pfam (PF12774)
Pfam (PF21499)
Pfam (PF12775)
Pfam (PF22597)
Pfam (PF12780)
Pfam (PF12777)
Pfam (PF00959)
Pfam (PF12781)
Saccharomyces cerevisiae (Baker's yeast)
Sequence modifications
A: 1364 - 3038 (UniProt: P36022)
PDBExternal DatabaseDetails
Gly 1363-expression tag
Gln 1849Glu 1849engineered mutation
A: 3126 - 3285 (UniProt: D9IEF7)
PDBExternal DatabaseDetails
Thr 3178Cys 54conflict
Ala 3221Cys 97conflict
Gly 3286-linker
Ser 3287-linker
Gly 3288-linker
Ser 3289-linker
Gly 3290-linker
Ser 3291-linker
A: 3292 - 4092 (UniProt: P36022)
PDBExternal DatabaseDetails
Gly 3120-linker
Ser 3121-linker
Gly 3122-linker
Ser 3123-linker
Gly 3124-linker
Ser 3125-linker
Asp 3742Asn 3742conflict
Val 3895Phe 3895conflict
Asp 4072Asn 4072conflict
Gly 4093-expression tag
Ser 4094-expression tag
Gly 4095-expression tag
Ser 4096-expression tag
Gly 4097-expression tag
Ser 4098-expression tag
His 4099-expression tag
His 4100-expression tag
His 4101-expression tag
His 4102-expression tag
His 4103-expression tag
His 4104-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight304889.9
All*Total formula weight304889.9
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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