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PDB: 461 件

5SVY
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MORC3 CW in complex with histone H3K4me1
分子名称: ACETATE ION, H3K4me1, MORC family CW-type zinc finger protein 3, ...
著者Tong, Q, Andrews, F.H, Kutateladze, T.G.
登録日2016-08-08
公開日2016-10-05
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Cell Rep, 16, 2016
2V89
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BU of 2v89 by Molmil
Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide at 1.1A resolution
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-03
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Rag2 Phd Finger Couples Histone H3 Lysine 4 Trimethylation with V(D)J Recombination.
Nature, 450, 2007
5SZC
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BU of 5szc by Molmil
Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with monomethylated K4 and acetylated K14
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ...
著者Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D.
登録日2016-08-13
公開日2017-08-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.193 Å)
主引用文献Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
5SZB
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Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with acetylated K14
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ...
著者Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D.
登録日2016-08-13
公開日2017-08-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
6BHD
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BU of 6bhd by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, SODIUM ION, ...
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
4UP0
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Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide
分子名称: HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
著者Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
登録日2014-06-11
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
5WXH
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BU of 5wxh by Molmil
Crystal structure of TAF3 PHD finger bound to H3K4me3
分子名称: Histone H3K4me3, Transcription initiation factor TFIID subunit 3, ZINC ION
著者Zhao, S, Huang, J, Li, H.
登録日2017-01-07
公開日2017-08-16
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.297 Å)
主引用文献Kinetic and high-throughput profiling of epigenetic interactions by 3D-carbene chip-based surface plasmon resonance imaging technology
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5FFV
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BU of 5ffv by Molmil
Crystal structure of the bromodomain of human BRPF1 in complex with H3K14ac histone peptide
分子名称: 1,2-ETHANEDIOL, Histone H3, Peregrin
著者Tallant, C, Nunez-Alonso, G, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S.
登録日2015-12-19
公開日2015-12-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of the bromodomain of human BRPF1 in complex with H3K14ac histone peptide
To Be Published
6BHE
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BU of 6bhe by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
4L7X
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BU of 4l7x by Molmil
Crystal structure of the DIDO PHD finger in complex with H3K4me3
分子名称: Death-inducer obliterator 1, Histone H3 peptide, ZINC ION
著者Tong, Q, Gatchalian, J, Kutateladze, T.G.
登録日2013-06-14
公開日2013-07-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Dido3 PHD Modulates Cell Differentiation and Division.
Cell Rep, 4, 2013
6BHI
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BU of 6bhi by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
3ASL
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BU of 3asl by Molmil
Structure of UHRF1 in complex with histone tail
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ...
著者Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M.
登録日2010-12-16
公開日2012-01-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
Proc.Natl.Acad.Sci.USA, 109, 2012
5TDR
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BU of 5tdr by Molmil
Set3 PHD finger in complex with histone H3K4me2
分子名称: Histone H3, SET domain-containing protein 3, SODIUM ION, ...
著者Andrews, F.H, Ali, M, Kutateladze, T.G.
登録日2016-09-19
公開日2016-11-02
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural Insight into Recognition of Methylated Histone H3K4 by Set3.
J. Mol. Biol., 429, 2017
4X3K
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BU of 4x3k by Molmil
Crystal structure of chromobox homolog 7 (CBX7) chromodomain with H3K27me3 peptide
分子名称: Chromobox protein homolog 7, H3K27me3 peptide, NICKEL (II) ION, ...
著者Ren, C, Zhou, M.M.
登録日2014-12-01
公開日2015-03-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
Chem.Biol., 22, 2015
6BHG
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BU of 6bhg by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
2RI7
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BU of 2ri7 by Molmil
Crystal structure of PHD finger-linker-bromodomain Y17E mutant from human BPTF in the H3(1-9)K4ME2 bound state
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Nucleosome-remodeling factor subunit BPTF, ...
著者Li, H, Patel, D.J.
登録日2007-10-10
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
5GH9
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BU of 5gh9 by Molmil
Crystal structure of CBP Bromodomain with H3K56ac peptide
分子名称: CREB-binding protein, Histone H3
著者Xu, L.
登録日2016-06-19
公開日2017-06-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structural insight into CBP bromodomain-mediated recognition of acetylated histone H3K56ac
FEBS J., 2017
3V43
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Crystal structure of MOZ
分子名称: ACETATE ION, Histone H3.1, Histone acetyltransferase KAT6A, ...
著者Qiu, Y, Li, F.
登録日2011-12-14
公開日2012-06-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription
Genes Dev., 26, 2012
5JIY
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BU of 5jiy by Molmil
Structure of G9a SET-domain with Histone H3K9norLeucine mutant peptide and bound S-adenosylmethionine
分子名称: Histone H3.1 mutant peptide with H3K9nor-leucine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
著者Jayaram, H, Bellon, S.F, Poy, F.
登録日2016-04-22
公開日2016-09-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
Proc.Natl.Acad.Sci.USA, 113, 2016
3MP6
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BU of 3mp6 by Molmil
Complex Structure of Sgf29 and dimethylated H3K4
分子名称: H3K4me2 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Li, J, Wu, M, Ruan, J, Zang, J.
登録日2010-04-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
8IJ0
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BU of 8ij0 by Molmil
Crystal structure of GAS41 YEATS domain in complex with H3K9ac peptide
分子名称: GLYCEROL, Histone H3.1, PENTAETHYLENE GLYCOL, ...
著者Kikuchi, M, Umehara, T.
登録日2023-02-24
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
3RIY
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BU of 3riy by Molmil
Sirt5 is an NAD-dependent protein lysine demalonylase and desuccinylase
分子名称: NAD-dependent deacetylase sirtuin-5, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION, ...
著者Zhou, Y, Hao, Q.
登録日2011-04-14
公開日2011-11-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
Science, 334, 2011
5SVX
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BU of 5svx by Molmil
MORC3 CW in complex with histone H3K4me3
分子名称: H3K4me3, MORC family CW-type zinc finger protein 3, ZINC ION
著者Tong, Q, Andrews, F.H, Kutateladze, T.G.
登録日2016-08-08
公開日2016-10-05
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Cell Rep, 16, 2016
7CFP
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BU of 7cfp by Molmil
Crystal structure of WDR5 in complex with a H3Q5ser peptide
分子名称: H3Q5ser peptide, SEROTONIN, WD repeat-containing protein 5
著者Zhao, J, Zhang, X, Zang, J.
登録日2020-06-27
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021
7CFQ
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Crystal structure of WDR5 in complex with H3K4me3Q5ser peptide
分子名称: 1,2-ETHANEDIOL, GLYCEROL, H3K4me3Q5ser peptide, ...
著者Zhao, J, Zhang, X, Zang, J.
登録日2020-06-27
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021

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