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PDB: 461 件

3KMT
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Crystal structure of vSET/SAH/H3 ternary complex
分子名称: A612L protein, Histone H3, S-ADENOSYL-L-HOMOCYSTEINE
著者Wei, H, Zhou, M.M.
登録日2009-11-11
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Dimerization of a viral SET protein endows its function.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KQI
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crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide
分子名称: CHLORIDE ION, GLYCEROL, H3K4Me3 peptide, ...
著者Wen, H, Li, J.Z, Song, T, Lu, M, Lee, M.
登録日2009-11-17
公開日2010-02-02
最終更新日2019-02-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.
J.Biol.Chem., 285, 2010
6IEU
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BU of 6ieu by Molmil
The structure of TRIM66 PHD-Bromo domain with unmodified H3 N terminal peptide
分子名称: ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-LYS-SER-THR-GLY, GLYCEROL, Tripartite motif-containing protein 66, ...
著者Chen, J.
登録日2018-09-17
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.787 Å)
主引用文献TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells.
Nat Commun, 10, 2019
4HON
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Crystal structure of human JMJD2D/KDM4D in complex with an H3K9me3 peptide and 2-oxoglutarate
分子名称: 1,3-PROPANDIOL, 2-OXOGLUTARIC ACID, Histone H3 Peptide, ...
著者Krishnan, S, Trievel, R.C.
登録日2012-10-22
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases.
Structure, 21, 2013
4QBS
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BU of 4qbs by Molmil
Crystal structure of DNMT3a ADD domain E545R mutant bound to H3T3ph peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H3, SULFATE ION, ...
著者Wang, H, Li, H.
登録日2014-05-08
公開日2015-05-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
To be Published
3SOU
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Structure of UHRF1 PHD finger in complex with histone H3 1-9 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
著者Rajakumara, E, Patel, D.J.
登録日2011-06-30
公開日2011-08-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8001 Å)
主引用文献PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
3AVR
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BU of 3avr by Molmil
Catalytic fragment of UTX/KDM6A bound with histone H3K27me3 peptide, N-oxyalylglycine, and Ni(II)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Histone H3, ...
著者Sengoku, T, Yokoyama, S.
登録日2011-03-07
公開日2011-10-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A
Genes Dev., 25, 2011
6YIF
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Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 1.8 A.
分子名称: Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ...
著者Serena, M, Elliott, P.R, Barr, F.A.
登録日2020-04-01
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
6F6D
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The catalytic domain of KDM6B in complex with H3(17-33)K18IA21M peptide
分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, Histone 3 peptide H3(17-33)K18IA21M, ...
著者Jones, S.E, Olsen, L, Gajhede, M.
登録日2017-12-05
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.81810677 Å)
主引用文献Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity.
Biochemistry, 57, 2018
5NND
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Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H3K9ac/K14ac)
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Histone H3
著者Filippakopoulos, P, Picaud, S, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C.
登録日2017-04-08
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Mol. Cell, 73, 2019
8DS8
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BU of 8ds8 by Molmil
Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide
分子名称: Histone H3.1, Trinucleotide repeat-containing gene 18 protein
著者Song, J.K, Lu, J.W.
登録日2022-07-21
公開日2023-08-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.
Nature, 623, 2023
5I3L
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DPF3b in complex with H3K14ac peptide
分子名称: 1,2-ETHANEDIOL, H3K14ac peptide, SODIUM ION, ...
著者Tempel, W, Liu, Y, Walker, J.R, Zhao, A, Qin, S, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2016-02-10
公開日2016-02-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of DPF3b in complex with an acetylated histone peptide.
J.Struct.Biol., 195, 2016
5JIN
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BU of 5jin by Molmil
Structure of G9a SET-domain with Histone H3K9M mutant peptide and bound S-adenosylmethionine
分子名称: Histone H3.1 peptide with K9M mutation, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
著者Jayaram, H, Bellon, S.F, Poy, F.
登録日2016-04-22
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
Proc.Natl.Acad.Sci.USA, 113, 2016
6MIO
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BU of 6mio by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9pr
分子名称: Histone H3K9pr, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6BHH
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BU of 6bhh by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, SULFATE ION, ...
著者Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-11-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
4UY4
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BU of 4uy4 by Molmil
1.86 A structure of human Spindlin-4 protein in complex with histone H3K4me3 peptide
分子名称: GLYCEROL, HISTONE H3K4ME3, SPINDLIN-4
著者Talon, R, Gileadi, C, Johansson, C, Burgess-Brown, N, Shrestha, L, von Delft, F, Krojer, T, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U.
登録日2014-08-28
公開日2014-09-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.862 Å)
主引用文献1.86 A Structure of Human Spindlin-4 Protein in Complex with Histone H3K4Me3 Peptide
To be Published
4LXL
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BU of 4lxl by Molmil
Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3
分子名称: H3 peptide, Lysine-specific demethylase 4B, NICKEL (II) ION, ...
著者Wang, W.-C, Chu, C.-H, Chen, C.-C.
登録日2013-07-30
公開日2014-07-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3
To be Published
7VZ4
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BU of 7vz4 by Molmil
Cryo-EM structure of human nucleosome core particle composed of the Widom 601L DNA sequence
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Takizawa, Y, Ho, C.-H, Sato, S, Danev, R, Kurumizaka, H.
登録日2021-11-15
公開日2023-05-17
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (1.89 Å)
主引用文献Methods for High Resolution Cryo-EM Analyses of Nucleosomes
To Be Published
5T0M
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BU of 5t0m by Molmil
A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading
分子名称: Histone-lysine N-methyltransferase EHMT2, S-ADENOSYL-L-HOMOCYSTEINE, S-ADENOSYLMETHIONINE, ...
著者Xu, K, Tong, L.
登録日2016-08-16
公開日2016-10-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.896 Å)
主引用文献A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading.
Elife, 5, 2016
4I51
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BU of 4i51 by Molmil
Methyltransferase domain of HUMAN EUCHROMATIC HISTONE METHYLTRANSFERASE 1, mutant Y1211A
分子名称: GLYCEROL, H3K9 NE-ALLYL PEPTIDE, Histone-lysine N-methyltransferase EHMT1, ...
著者Dong, A, Zeng, H, Walker, J.R, Islam, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Lou, M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2012-11-28
公開日2012-12-19
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4A7J
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BU of 4a7j by Molmil
Symmetric Dimethylation of H3 Arginine 2 is a Novel Histone Mark that Supports Euchromatin Maintenance
分子名称: HISTONE H3.1T, WD REPEAT-CONTAINING PROTEIN 5
著者Migliori, V, Muller, J, Phalke, S, Low, D, Bezzi, M, ChuenMok, W, Gunaratne, J, Capasso, P, Bassi, C, Cecatiello, V, DeMarco, A, Blackstock, W, Kuznetsov, V, Amati, B, Mapelli, M, Guccione, E.
登録日2011-11-14
公開日2012-01-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Symmetric Dimethylation of H3R2 is a Newly Identified Histone Mark that Supports Euchromatin Maintenance
Nat.Struct.Mol.Biol., 19, 2012
5T1G
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BU of 5t1g by Molmil
chromo shadow domain of CBX1 in complex with a histone peptide
分子名称: Chromobox protein homolog 1, Histone H3.1, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2016-08-19
公開日2016-09-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献chromo shadow domain of CBX1 in complex with a histone peptide
To Be Published
6MIN
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BU of 6min by Molmil
Crystal structure of Taf14 YEATS domain G82A mutant in complex with histone H3K9cr
分子名称: Histone H3K9cr, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
3O34
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BU of 3o34 by Molmil
Crystal structure of TRIM24 PHD-Bromo complexed with H3(13-32)K23ac peptide
分子名称: BIOTIN, Histone H3.1, Transcription intermediary factor 1-alpha, ...
著者Wang, Z, Patel, D.J.
登録日2010-07-23
公開日2010-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
3LQJ
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Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me3 peptide
分子名称: Histone H3, MLL1 PHD3-Bromo, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2010-02-09
公開日2010-07-07
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010

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件を2024-07-03に公開中

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