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PDB: 198 件
2R93
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Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Lehmann, E, Brueckner, F, Cramer, P.
登録日2007-09-12
公開日2007-11-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Molecular basis of RNA-dependent RNA polymerase II activity.
Nature, 450, 2007
2JA6
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CPD lesion containing RNA Polymerase II elongation complex B
分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TTP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ...
著者Brueckner, F, Hennecke, U, Carell, T, Cramer, P.
登録日2006-11-23
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献CPD damage recognition by transcribing RNA polymerase II.
Science, 315, 2007
7ZSA
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Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B)
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Wang, H, Cramer, P.
登録日2022-05-06
公開日2022-11-16
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
7ML1
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RNA polymerase II pre-initiation complex (PIC2)
分子名称: BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ...
著者Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K.
登録日2021-04-27
公開日2022-02-02
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
5C4X
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Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-18
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
1Y1W
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Complete RNA Polymerase II elongation complex
分子名称: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
著者Cramer, P, Kettenberger, H, Armache, K.-J.
登録日2004-11-19
公開日2005-01-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16, 2004
1Y1Y
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RNA Polymerase II-TFIIS-DNA/RNA complex
分子名称: 5'-D(P*TP*AP*CP*GP*CP*CP*T)-3', 5'-R(P*AP*GP*GP*C)-3', DNA-directed RNA polymerase II 13.6 kDa polypeptide, ...
著者Cramer, P, Kettenberger, H, Armache, K.-J.
登録日2004-11-19
公開日2004-12-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.
Mol.Cell, 16, 2004
5C4J
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BU of 5c4j by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-18
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
3H3V
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Yeast RNAP II containing poly(A)-signal sequence in the active site
分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*GP*CP*TP*GP*CP*TP*TP*TP*AP*TP*TP*GP*CP*AP*TP*T)-3', 5'-D(*CP*AP*GP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*CP*AP*AP*UP*AP*AP*A)-3', ...
著者Dengl, S, Cramer, P.
登録日2009-04-17
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro
J.Biol.Chem., 284, 2009
1NIK
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Wild Type RNA Polymerase II
分子名称: DNA-directed RNA polymerase I, II and III 23 kDa polypeptide, DNA-directed RNA polymerase II, ...
著者Bushnell, D.A, Kornberg, R.D.
登録日2002-12-24
公開日2003-04-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Complete, 12-subunit RNA Polymerase II at 4.1-A resolution: implications for the initiation of transcription.
Proc.Natl.Acad.Sci.USA, 100, 2003
4X67
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Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions.
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Wang, L, Chong, J, Wang, D.
登録日2014-12-07
公開日2015-02-04
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.
Proc.Natl.Acad.Sci.USA, 112, 2015
2B8K
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12-subunit RNA Polymerase II
分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ...
著者Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J.
登録日2005-10-07
公開日2006-06-20
最終更新日2012-06-13
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model.
Structure, 14, 2006
1NT9
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BU of 1nt9 by Molmil
Complete 12-subunit RNA polymerase II
分子名称: DNA-DIRECTED RNA POLYMERASE II 13.6 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT, ...
著者Armache, K.-J, Kettenberger, H, Cramer, P.
登録日2003-01-29
公開日2003-04-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Architecture of initiation-competent 12-subunit RNA polymerase II
Proc.Natl.Acad.Sci.USA, 100, 2003
5C4A
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BU of 5c4a by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Saphr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-17
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
1R9S
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BU of 1r9s by Molmil
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE
分子名称: DNA strand, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ...
著者Westover, K.D, Bushnell, D.A, Kornberg, R.D.
登録日2003-10-30
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (4.25 Å)
主引用文献Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell(Cambridge,Mass.), 119, 2004
3QT1
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BU of 3qt1 by Molmil
RNA polymerase II variant containing A Chimeric RPB9-C11 subunit
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Ruan, W, Lehmann, E, Thomm, M, Kostrewa, D, Cramer, P.
登録日2011-02-22
公開日2011-03-23
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Evolution of two modes of intrinsic RNA polymerase transcript cleavage.
J.Biol.Chem., 286, 2011
7UIG
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Mediator-PIC Early (Mediator A)
分子名称: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
2NVZ
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RNA Polymerase II elongation complex with UTP, updated 11/2006
分子名称: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-14
公開日2006-12-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
3K1F
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BU of 3k1f by Molmil
Crystal structure of RNA Polymerase II in complex with TFIIB
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Kostrewa, D, Zeller, M.E, Armache, K.-J, Seizl, M, Leike, K, Thomm, M, Cramer, P.
登録日2009-09-27
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献RNA polymerase II-TFIIB structure and mechanism of transcription initiation.
Nature, 462, 2009
5FYW
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Transcription initiation complex structures elucidate DNA opening (OC)
分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
著者Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P.
登録日2016-03-10
公開日2016-05-18
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.35 Å)
主引用文献Transcription Initiation Complex Structures Elucidate DNA Opening
Nature, 533, 2016
8TVS
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Cryo-EM structure of backtracked Pol II in complex with Rad26
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Sarsam, R.D, Lahiri, I, Leschziner, A.E.
登録日2023-08-18
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
6I84
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BU of 6i84 by Molmil
Structure of transcribing RNA polymerase II-nucleosome complex
分子名称: DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ...
著者Farnung, L, Vos, S.M, Cramer, P.
登録日2018-11-19
公開日2019-01-02
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure of transcribing RNA polymerase II-nucleosome complex.
Nat Commun, 9, 2018
1R5U
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RNA POLYMERASE II TFIIB COMPLEX
分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ...
著者Bushnell, D.A, Westover, K.D, Davis, R, Kornberg, R.D.
登録日2003-10-13
公開日2004-02-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms.
Science, 303, 2004
4GWQ
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Structure of the Mediator Head Module from S. cerevisiae in complex with the carboxy-terminal domain (CTD) of RNA Polymerase II Rpb1 subunit
分子名称: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, ...
著者Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D.
登録日2012-09-03
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II.
Proc.Natl.Acad.Sci.USA, 109, 2012
1Y77
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Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP
分子名称: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*T*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*G)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
著者Kettenberger, H, Armache, K.-J, Cramer, P.
登録日2004-12-08
公開日2005-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16, 2004

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