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PDB: 13 件
5H65
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BU of 5h65 by Molmil
Crystal structure of human POT1 and TPP1
分子名称: Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION
著者Chen, C, Wu, J, Lei, M.
登録日2016-11-10
公開日2017-05-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer.
Nat Commun, 8, 2017
5UN7
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BU of 5un7 by Molmil
Structure of the human POT1-TPP1 telomeric complex
分子名称: Adrenocortical dysplasia protein homolog, POTASSIUM ION, Protection of telomeres protein 1, ...
著者Rice, C, Doukov, T, Skordalakes, E.
登録日2017-01-30
公開日2017-04-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and functional analysis of the human POT1-TPP1 telomeric complex.
Nat Commun, 8, 2017
5XYF
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BU of 5xyf by Molmil
Crystal structure of the human TIN2-TPP1-TRF2 telomeric complex
分子名称: Adrenocortical dysplasia protein homolog, TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2
著者Hu, C, Chen, Y.
登録日2017-07-07
公開日2017-12-13
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex.
Cell Res., 27, 2017
2I46
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BU of 2i46 by Molmil
Crystal structure of human TPP1
分子名称: Adrenocortical dysplasia protein homolog
著者Wang, F, Podell, E.R, Zaug, A.J, Yang, Y.T, Baciu, P, Else, T, Hammer, G.D, Cech, T.R, Lei, M.
登録日2006-08-21
公開日2006-11-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The POT1-TPP1 telomere complex is a telomerase processivity factor.
Nature, 445, 2007
7S1T
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BU of 7s1t by Molmil
Structure of the human POT1-TPP1 complex
分子名称: Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION
著者Aramburu, T, Skordalakes, E.
登録日2021-09-02
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance.
Comput Struct Biotechnol J, 20, 2022
5I2Y
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BU of 5i2y by Molmil
Crystal Structure of TPP1 K170A
分子名称: Adrenocortical dysplasia protein homolog
著者Nandakumar, J, Smith, E.M.
登録日2016-02-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Proc.Natl.Acad.Sci.USA, 113, 2016
5I2X
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BU of 5i2x by Molmil
Crystal Structure of TPP1 K170del
分子名称: Adrenocortical dysplasia protein homolog
著者Nandakumar, J, Smith, E.
登録日2016-02-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Proc.Natl.Acad.Sci.USA, 113, 2016
7QXA
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BU of 7qxa by Molmil
Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-26
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
7TRE
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BU of 7tre by Molmil
Human telomerase catalytic core with shelterin protein TPP1
分子名称: Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
8SOJ
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BU of 8soj by Molmil
Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the absence of telomeric ssDNA
分子名称: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ...
著者Cai, S.W.
登録日2023-04-28
公開日2023-06-07
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献POT1 recruits and regulates CST-Pol alpha /Primase at human telomeres.
Biorxiv, 2023
7QXS
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BU of 7qxs by Molmil
Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-27
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
7QXB
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BU of 7qxb by Molmil
Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-26
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
8SOK
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BU of 8sok by Molmil
Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the presence of telomeric ssDNA
分子名称: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ...
著者Cai, S.W.
登録日2023-04-28
公開日2023-06-07
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献POT1 recruits and regulates CST-Pol alpha /Primase at human telomeres.
Biorxiv, 2023

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件を2024-07-10に公開中

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