8A40
| Structure of mammalian Pol II-TFIIS elongation complex | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P. | 登録日 | 2022-06-09 | 公開日 | 2023-08-23 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of a backtracked hexasomal intermediate of nucleosome transcription. Mol.Cell, 82, 2022
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7ZWD
| Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | 登録日 | 2022-05-19 | 公開日 | 2022-11-30 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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8WAW
| De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt downstream of TSS | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-08 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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8OEU
| Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | 登録日 | 2023-03-13 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8OF0
| Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | 登録日 | 2023-03-13 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8S51
| RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8B3F
| Pol II-CSB-CSA-DDB1-ELOF1 | 分子名称: | DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... | 著者 | Kokic, G, Cramer, P. | 登録日 | 2022-09-16 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Pol II-CSB-CSA-DDB1-ELOF1 structure. To Be Published
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6TED
| Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | 分子名称: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | 著者 | Vos, S.M, Farnung, L, Cramer, P. | 登録日 | 2019-11-11 | 公開日 | 2020-07-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation. Nat.Struct.Mol.Biol., 27, 2020
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6GMH
| Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | 分子名称: | CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ... | 著者 | Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P. | 登録日 | 2018-05-26 | 公開日 | 2018-08-22 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature, 560, 2018
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6GML
| Structure of paused transcription complex Pol II-DSIF-NELF | 分子名称: | DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. | 登録日 | 2018-05-27 | 公開日 | 2018-09-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of paused transcription complex Pol II-DSIF-NELF. Nature, 560, 2018
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8P4B
| Structural insights into human co-transcriptional capping - structure 2 | 分子名称: | DNA (35-MER), DNA (5'-D(P*AP*GP*CP*GP*GP*CP*GP*GP*AP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*AP*GP*CP*TP*G)-3'), DNA-directed RNA polymerase II subunit E, ... | 著者 | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | 登録日 | 2023-05-20 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
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8UIS
| Structure of transcription complex Pol II-DSIF-NELF-TFIIS | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | 著者 | Su, B.G, Vos, S.M. | 登録日 | 2023-10-10 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
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7OKX
| Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | 登録日 | 2021-05-18 | 公開日 | 2021-07-14 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
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8A3Y
| Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P. | 登録日 | 2022-06-09 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of a backtracked hexasomal intermediate of nucleosome transcription. Mol.Cell, 82, 2022
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7EGB
| TFIID-based holo PIC on SCP promoter | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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8S54
| RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state b (composite structure) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabber, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8S55
| RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state a (composite structure) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8S5N
| RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | 登録日 | 2024-02-24 | 公開日 | 2024-04-10 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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7ZX7
| Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | 登録日 | 2022-05-20 | 公開日 | 2022-11-30 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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7OZN
| RNA Polymerase II dimer (Class 1) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Aibara, S, Dienemann, C, Cramer, P. | 登録日 | 2021-06-28 | 公開日 | 2021-10-06 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
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8UHA
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7PKS
| Structural basis of Integrator-mediated transcription regulation | 分子名称: | DNA Template, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Fianu, I, Chen, Y, Dienemann, C, Cramer, P. | 登録日 | 2021-08-26 | 公開日 | 2021-12-08 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of Integrator-mediated transcription regulation. Science, 374, 2021
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7B0Y
| Structure of a transcribing RNA polymerase II-U1 snRNP complex | 分子名称: | 145-nt RNA, DNA-directed RNA polymerase II subunit D, DNA-directed RNA polymerase II subunit E, ... | 著者 | Zhang, S, Aibara, S, Vos, S.M, Agafonov, D.E, Luehrmann, R, Cramer, P. | 登録日 | 2020-11-23 | 公開日 | 2021-01-13 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of a transcribing RNA polymerase II-U1 snRNP complex. Science, 371, 2021
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8P4A
| Structural insights into human co-transcriptional capping - structure 1 | 分子名称: | DNA (29-MER), DNA (38-MER), DNA-directed RNA polymerase II subunit E, ... | 著者 | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | 登録日 | 2023-05-20 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
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8P4D
| Structural insights into human co-transcriptional capping - structure 4 | 分子名称: | DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... | 著者 | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | 登録日 | 2023-05-20 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
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