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PDB: 148 件

4UDU
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Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor
分子名称: ENTEROTOXIN TYPE E, PROTEIN TRBV7-9, T-CELL RECEPTOR BETA-2 CHAIN C REGION, ...
著者Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K.
登録日2014-12-11
公開日2015-06-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Staphylococcal Enterotoxin E in Complex with Tcr Defines the Role of Tcr Loop Positioning in Superantigen Recognition.
Plos One, 10, 2015
1BD2
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BU of 1bd2 by Molmil
COMPLEX BETWEEN HUMAN T-CELL RECEPTOR B7, VIRAL PEPTIDE (TAX) AND MHC CLASS I MOLECULE HLA-A 0201
分子名称: BETA-2 MICROGLOBULIN, HLA-A 0201, T CELL RECEPTOR ALPHA, ...
著者Ding, Y.-H, Smith, K.J, Garboczi, D.N, Utz, U, Biddison, W.E, Wiley, D.C.
登録日1998-05-12
公開日1998-08-19
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.
Immunity, 8, 1998
3SCM
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BU of 3scm by Molmil
Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-isoglobotrihexosylceramide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Clarke, A.J, Rossjohn, J.
登録日2011-06-08
公開日2011-10-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
2AK4
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BU of 2ak4 by Molmil
Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide
分子名称: Beta-2-microglobulin, EBV peptide LPEPLPQGQLTAY, HLA-B35 variant, ...
著者Tynan, F.E, Burrows, S.R, Buckle, A.M, Clements, C.S, Borg, N.A, Miles, J.J, Beddoe, T, Whisstock, J.C, Wilce, M.C, Silins, S.L, Burrows, J.M, Kjer-Nielsen, L, Konstenko, L, Purcell, A.W, McCluskey, J, Rossjohn, J.
登録日2005-08-03
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Nat.Immunol., 6, 2005
4PRP
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BU of 4prp by Molmil
Crystal structure of TK3 TCR-HLA-B*35:01-HPVG-Q5 complex
分子名称: Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, MHC class I antigen, ...
著者Yu Chih, L, Rossjohn, J, Gras, S.
登録日2014-03-06
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
J.Biol.Chem., 289, 2014
4PRH
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Crystal structure of TK3 TCR-HLA-B*35:08-HPVG-D5 complex
分子名称: Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, MHC class I antigen, ...
著者Yu Chih, L, Rossjohn, J, Gras, S.
登録日2014-03-05
公開日2014-04-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
J.Biol.Chem., 289, 2014
1MI5
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BU of 1mi5 by Molmil
The crystal structure of LC13 TcR in complex with HLAB8-EBV peptide complex
分子名称: Epstein Barr Virus peptide, MHC heavy chain, TcR alpha chain, ...
著者Kjer-Nielsen, L, Clements, C.S, Purcell, A.W, Brooks, A.G, Whisstock, J.C, Burrows, S.R, McCluskey, J, Rossjohn, J.
登録日2002-08-21
公開日2003-02-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Structural Basis for the Selection of Dominant alphabeta T Cell Receptors in Antiviral Immunity
IMMUNITY, 18, 2003
3O4L
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BU of 3o4l by Molmil
Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BSLF2/BMLF1 protein, Beta-2-microglobulin, ...
著者Miles, J.J, Bulek, A.M, Cole, D.K, Gostick, E, Schauenburg, J.A, Dolton, G, Venturi, V, Davenport, M.P, Tan, M.P, Burrows, S.R, Wooldridge, L, Price, D.A, Rizkallah, P.J, Sewell, A.K.
登録日2010-07-27
公開日2011-01-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.
Plos Pathog., 6, 2010
5KS9
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BU of 5ks9 by Molmil
Bel502-DQ8-glia-alpha1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bel502 TCR alpha TRAV20*01, Bel502 TCR beta TRBV9*01, ...
著者Petersen, J, Rossjohn, J, Reid, H.H.
登録日2016-07-08
公開日2016-09-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution.
Structure, 24, 2016
2GJ6
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BU of 2gj6 by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
分子名称: 3-INDOLEBUTYRIC ACID, A6-Tcr, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-03-30
公開日2006-10-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献T Cell Receptor Recognition via Cooperative Conformational Plasticity.
J.Mol.Biol., 363, 2006
3QEQ
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BU of 3qeq by Molmil
The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(27-35) nonameric peptide
分子名称: Beta-2-microglobulin, DMF4 alpha chain, DMF4 beta chain, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2011-01-20
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
4MXQ
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BU of 4mxq by Molmil
42F3 TCR pCPC5/H-2Ld Complex
分子名称: 42F3 alpha VmVh chimera, 42F3 beta VmVh chimera, H-2 class I histocompatibility antigen, ...
著者Birnbaum, M.E, Adams, J.J, Garcia, K.C.
登録日2013-09-26
公開日2015-08-19
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
1AO7
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BU of 1ao7 by Molmil
COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201
分子名称: BETA-2 MICROGLOBULIN, ETHYL MERCURY ION, HLA-A 0201, ...
著者Garboczi, D.N, Ghosh, P, Utz, U, Fan, Q.R, Biddison, W.E, Wiley, D.C.
登録日1997-07-21
公開日1997-09-17
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the complex between human T-cell receptor, viral peptide and HLA-A2.
Nature, 384, 1996
2CDG
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BU of 2cdg by Molmil
Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide-specific T cell receptors (TCR 5B)
分子名称: TCR 5E
著者Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y.
登録日2006-01-23
公開日2006-03-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
4Y16
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BU of 4y16 by Molmil
Crystal structure of the mCD1d/NC-aGC/iNKTCR ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zajonc, D.M, Nemcovic, M.
登録日2015-02-06
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Lipid and Carbohydrate Modifications of alpha-Galactosylceramide Differently Influence Mouse and Human Type I Natural Killer T Cell Activation.
J.Biol.Chem., 290, 2015
1FYT
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CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, HLA-DR1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ HA1 PEPTIDE CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ...
著者Hennecke, J, Carfi, A, Wiley, D.C.
登録日2000-10-03
公開日2000-11-08
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1.
EMBO J., 19, 2000
3KPR
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BU of 3kpr by Molmil
Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLKAWTF a mimotope
分子名称: Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
2ESV
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BU of 2esv by Molmil
Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
著者Hoare, H.L, Rossjohn, J.
登録日2005-10-27
公開日2006-03-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for a major histocompatibility complex class Ib-restricted T cell response
Nat.Immunol., 7, 2006
2EYT
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A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
分子名称: NKT15
著者Kjer-Nielsen, L, Borg, N.A.
登録日2005-11-09
公開日2006-03-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
J.Exp.Med., 203, 2006
5BRZ
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BU of 5brz by Molmil
MAGE-A3 reactive TCR in complex with MAGE-A3 in HLA-A1
分子名称: Beta-2-microglobulin, GLU-VAL-ASP-PRO-ILE-GLY-HIS-LEU-TYR, HLA class I histocompatibility antigen, ...
著者Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donnellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, LomaX, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K.
登録日2015-06-01
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep, 6, 2016
3QDG
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The complex between TCR DMF5 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide
分子名称: Beta-2-microglobulin, DMF5 alpha chain, DMF5 beta chain, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2011-01-18
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
3PWP
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BU of 3pwp by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the bound HuD peptide
分子名称: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-12-08
公開日2011-03-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3QIB
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Crystal structure of the 2B4 TCR in complex with MCC/I-Ek
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 beta chain, DI(HYDROXYETHYL)ETHER, ...
著者Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C.
登録日2011-01-26
公開日2011-04-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
7RYN
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CD1a-sulfatide-gdTCR complex
分子名称: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wegrecki, M, Le Nours, J, Rossjohn, J.
登録日2021-08-25
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors.
Nat Commun, 13, 2022
2NX5
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Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A
分子名称: Beta-2-microglobulin, EBV peptide, EPLPQGQLTAY, ...
著者Tynan, F.E, Reid, H.H, Rossjohn, J.
登録日2006-11-16
公開日2007-02-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Nat.Immunol., 8, 2007

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