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PDB: 6312 件
5J73
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BU of 5j73 by Molmil
De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity
分子名称: protein design 2L4HC2_9
著者Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G.
登録日2016-04-05
公開日2016-05-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5J2L
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BU of 5j2l by Molmil
De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity
分子名称: protein design 2L4HC2_11
著者Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G.
登録日2016-03-29
公開日2016-05-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
7ZDZ
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BU of 7zdz by Molmil
Cryo-EM structure of the human inward-rectifier potassium 2.1 channel (Kir2.1)
分子名称: Inward rectifier potassium channel 2, POTASSIUM ION, STRONTIUM ION
著者Fernandes, C.A.H, Venien-Bryan, C, Fagnen, C, Zuniga, D.
登録日2022-03-30
公開日2022-09-28
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryo-electron microscopy unveils unique structural features of the human Kir2.1 channel.
Sci Adv, 8, 2022
5JEQ
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BU of 5jeq by Molmil
Fragment of nitrate/nitrite sensor histidine kinase NarQ (R50K) in symmetric apo state
分子名称: Nitrate/nitrite sensor protein NarQ, PHOSPHATE ION
著者Gushchin, I, Melnikov, I, Polovinkin, V, Ishchenko, A, Popov, A, Gordeliy, V.
登録日2016-04-18
公開日2017-05-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of transmembrane signaling by sensor histidine kinases.
Science, 356, 2017
7YV9
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BU of 7yv9 by Molmil
Cryo-EM structure of full-length Myosin Va in the autoinhibited state
分子名称: Calmodulin-1, Unconventional myosin-Va
著者Niu, F, Wei, Z.
登録日2022-08-19
公開日2022-12-21
実験手法ELECTRON MICROSCOPY (4.78 Å)
主引用文献Autoinhibition and activation mechanisms revealed by the triangular-shaped structure of myosin Va.
Sci Adv, 8, 2022
7YSE
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BU of 7yse by Molmil
Crystal structure of E. coli heterotetrameric GlyRS in complex with tRNA
分子名称: Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit, MAGNESIUM ION, ...
著者Han, L, Ju, Y, Zhou, H.
登録日2022-08-12
公開日2023-02-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.907 Å)
主引用文献The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements.
Sci Adv, 9, 2023
6DFG
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BU of 6dfg by Molmil
BG505 MD39 SOSIP trimer in complex with mature BG18 fragment antigen binding
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Ozorowski, G, Steichen, J.M, Schief, W.R, Ward, A.B.
登録日2018-05-14
公開日2019-11-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.42 Å)
主引用文献A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
5FWM
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BU of 5fwm by Molmil
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日2016-02-18
公開日2016-07-06
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016
5FWX
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BU of 5fwx by Molmil
Crystal structure of the AMPA receptor GluA2/A4 N-terminal domain heterodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMATE RECEPTOR 2, GLUTAMATE RECEPTOR 4, ...
著者Garcia-Nafria, J, Herguedas, B, Greger, I.H.
登録日2016-02-21
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Organization of Heteromeric Ampa-Type Glutamate Receptors.
Science, 352, 2016
5FBK
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BU of 5fbk by Molmil
Crystal structure of the extracellular domain of human calcium sensing receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ...
著者Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J.
登録日2015-12-14
公開日2016-06-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
5FHB
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BU of 5fhb by Molmil
Crystal Structure of Protective Ebola Virus Antibody 100
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Antibody 100 Fab heavy chain, ...
著者Gilman, M.S.A, McLellan, J.S.
登録日2015-12-21
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.973 Å)
主引用文献Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
6DFW
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BU of 6dfw by Molmil
TCR 8F10 in complex with IAg7-p8G9E
分子名称: 8F10 alpha chain, 8F10 beta chain, H-2 class II histocompatibility antigen, ...
著者Wang, Y, Dai, S.
登録日2018-05-15
公開日2019-04-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
5FTM
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BU of 5ftm by Molmil
Cryo-EM structure of human p97 bound to ATPgS (Conformation II)
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Banerjee, S, Bartesaghi, A, Merk, A, Rao, P, Bulfer, S.L, Yan, Y, Green, N, Mroczkowski, B, Neitz, R.J, Wipf, P, Falconieri, V, Deshaies, R.J, Milne, J.L.S, Huryn, D, Arkin, M, Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FWY
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BU of 5fwy by Molmil
Crystal structure of the AMPA receptor GluA2/A3 N-terminal domain heterodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMATE RECEPTOR 2, GLUTAMATE RECEPTOR 3, ...
著者Herguedas, B, Garcia-Nafria, J, Greger, I.H.
登録日2016-02-21
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structure and Organization of Heteromeric Ampa-Type Glutamate Receptors.
Science, 352, 2016
5FA5
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BU of 5fa5 by Molmil
Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Histone H4, Methylosome protein 50, ...
著者Sprague, E.R, McNamara, J.T.
登録日2015-12-10
公開日2016-02-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Science, 351, 2016
6DFS
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BU of 6dfs by Molmil
mouse TCR I.29 in complex with IAg7-p8E9E6ss
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A-D alpha chain, ...
著者Wang, Y, Dai, S.
登録日2018-05-15
公開日2019-04-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
5F9R
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BU of 5f9r by Molmil
Crystal structure of catalytically-active Streptococcus pyogenes CRISPR-Cas9 in complex with single-guided RNA and double-stranded DNA primed for target DNA cleavage
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (30-MER), DNA (5'-D(P*AP*TP*GP*AP*GP*AP*CP*GP*CP*TP*GP*GP*AP*GP*TP*AP*CP*AP*C)-3'), ...
著者Jiang, F, Doudna, J.A.
登録日2015-12-10
公開日2016-01-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
Science, 351, 2016
6DMY
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BU of 6dmy by Molmil
Cryo-EM structure of human Ptch1 and ShhN complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Yan, N, Gong, X, Qian, H.W.
登録日2018-06-05
公開日2018-07-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
5FHC
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BU of 5fhc by Molmil
Crystal Structure of Protective Human Antibodies 100 and 114 in Complex with Ebola Virus Fusion Glycoprotein (GP)
分子名称: Antibody 100 Fab heavy chain, Antibody 100 Fab light chain, Antibody 114 Fab heavy chain, ...
著者Gilman, M.S.A, McLellan, J.S.
登録日2015-12-21
公開日2016-03-16
最終更新日2016-03-30
実験手法X-RAY DIFFRACTION (6.704 Å)
主引用文献Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5FLC
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BU of 5flc by Molmil
Architecture of human mTOR Complex 1 - 5.9 Angstrom reconstruction
分子名称: FKBP, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, REGULATORY-ASSOCIATED PROTEIN OF MTOR, ...
著者Aylett, C.H.S, Sauer, E, Imseng, S, Boehringer, D, Hall, M.N, Ban, N, Maier, T.
登録日2015-10-23
公開日2015-12-30
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Architecture of Human Mtor Complex 1
Science, 351, 2016
5FTK
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BU of 5ftk by Molmil
Cryo-EM structure of human p97 bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE
著者Banerjee, S, Bartesaghi, A, Merk, A, Rao, P, Bulfer, S.L, Yan, Y, Green, N, Mroczkowski, B, Neitz, R.J, Wipf, P, Falconieri, V, Deshaies, R.J, Milne, J.L.S, Huryn, D, Arkin, M, Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FWK
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BU of 5fwk by Molmil
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日2016-02-17
公開日2016-07-06
最終更新日2019-08-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016
5FUU
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BU of 5fuu by Molmil
Ectodomain of cleaved wild type JR-FL EnvdCT trimer in complex with PGT151 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lee, J.H, Ward, A.B.
登録日2016-01-29
公開日2016-03-09
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-Em Structure of a Native, Fully Glycosylated and Cleaved HIV-1 Envelope Trimer
Science, 351, 2016
5FTL
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BU of 5ftl by Molmil
Cryo-EM structure of human p97 bound to ATPgS (Conformation I)
分子名称: ADENOSINE-5'-DIPHOSPHATE, TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE
著者Banerjee, S, Bartesaghi, A, Merk, A, Rao, P, Bulfer, S.L, Yan, Y, Green, N, Mroczkowski, B, Neitz, R.J, Wipf, P, Falconieri, V, Deshaies, R.J, Milne, J.L.S, Huryn, D, Arkin, M, Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FWP
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BU of 5fwp by Molmil
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日2016-02-18
公開日2016-10-26
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016

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